{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,20]],"date-time":"2026-06-20T13:54:46Z","timestamp":1781963686904,"version":"3.54.5"},"reference-count":18,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2018,4,12]],"date-time":"2018-04-12T00:00:00Z","timestamp":1523491200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Special Care in Dentistry"],"published-print":{"date-parts":[[2018,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>Leukemic infiltration of the gingival tissue associated or not with gingival enlargement may be the first manifestation of acute leukemia, despite being rarely reported in the literature. A 10\u2010year\u2010old female patient presented with a 1\u2010month history of an asymptomatic, firm, and pinkish\u2010red generalized gingival overgrowth. There was no bone resorption. Incisional biopsy of the gingival tissue was performed, with histopathological examination revealing a diffuse and hypercellular infiltration of monocytoid cells. The patient was referred to a hematologist and underwent a bone marrow biopsy, which led to a conclusive diagnosis of acute myeloid leukemia. The patient was treated with chemotherapy and we observed regression of gingival enlargement after 4 weeks from the initial therapy.<\/jats:p>","DOI":"10.1111\/scd.12283","type":"journal-article","created":{"date-parts":[[2018,4,12]],"date-time":"2018-04-12T12:14:11Z","timestamp":1523535251000},"page":"160-162","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Gingival leukemic infiltration as the first manifestation of acute myeloid leukemia"],"prefix":"10.1111","volume":"38","author":[{"given":"Karin S\u00e1","family":"Fernandes","sequence":"first","affiliation":[{"name":"Department of Stomatology University of S\u00e3o Paulo School of Dentistry  S\u00e3o Paulo, Brazil"},{"name":"Department of Orthodontics and Radiology University of S\u00e3o Paulo City  UNICID, S\u00e3o Paulo, 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