{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T05:45:36Z","timestamp":1777355136898,"version":"3.51.4"},"reference-count":10,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2018,9,12]],"date-time":"2018-09-12T00:00:00Z","timestamp":1536710400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Special Care in Dentistry"],"published-print":{"date-parts":[[2018,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Griscelli syndrome (GS) is an autosomal\u2010recessive disorder of the vesicle transport and membrane trafficking system first identified by Griscelli et\u00a0al in 1978. The three types of GS have specific genetic defects and systemic manifestations apart from classic partial pigmentary dilution, resulting in hypopigmentation of skin and silvery hair. GS\u2010II occurs due to a defect in the Rab27a gene and is characterized by primary immune deficiency along with accelerated phases of a hemophagocytic lymphohistiocytosis (HLH) crisis. This rare disorder has been widely studied for dermatological, hematological, and neurological manifestations; however, the oral features and presentations have not been elucidated in detail. This report presents a case of a 4\u2010year\u2010old male with known mutation c.550C\u00a0&gt;\u00a0T or p.R184X mutation (ENST00000396307) in Rab27a with oral features.<\/jats:p>","DOI":"10.1111\/scd.12328","type":"journal-article","created":{"date-parts":[[2018,9,12]],"date-time":"2018-09-12T11:19:44Z","timestamp":1536751184000},"page":"421-425","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Oral features of Griscelli syndrome type II: A rare case report"],"prefix":"10.1111","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6747-5110","authenticated-orcid":false,"given":"Nitesh","family":"Tewari","sequence":"first","affiliation":[{"name":"Pedodontics &amp; Preventive Dentistry Centre for Dental Education and Research All India Institute of Medical Sciences  New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anju","family":"Rajwar","sequence":"additional","affiliation":[{"name":"Pedodontics &amp; Preventive Dentistry Centre for Dental Education and Research All India Institute of Medical Sciences  New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vijay Prakash","family":"Mathur","sequence":"additional","affiliation":[{"name":"Pedodontics &amp; Preventive Dentistry Centre for Dental Education and Research All India Institute of Medical Sciences  New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Prabhat Kumar","family":"Chaudhari","sequence":"additional","affiliation":[{"name":"Orthodontics and Dentofacial Deformities Centre for Dental Education and Research All India Institute of Medical Sciences  New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,9,12]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(78)90858-6"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.5582\/irdr.2016.01084"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.4103\/neuroindia.NI_762_16"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.4103\/0019-5154.30292"},{"key":"e_1_2_9_6_1","first-page":"944","article-title":"Griscelli syndrome: rab 27a mutation","volume":"41","author":"Sheela SR","year":"2004","journal-title":"Indian Pediatr"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/76024"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1177\/0883073808315409"},{"key":"e_1_2_9_9_1","first-page":"113","article-title":"Griscelli syndrome type 2: a rare and fatal syndrome in a South Indian boy","volume":"59","author":"Rajyalakshmi R","year":"2016","journal-title":"Indian J Pathol Microbiol"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0889-5406(05)81596-3"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/pch\/pxx155"}],"container-title":["Special Care in Dentistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fscd.12328","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/scd.12328","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,15]],"date-time":"2023-09-15T09:20:25Z","timestamp":1694769625000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/scd.12328"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9,12]]},"references-count":10,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2018,11]]}},"alternative-id":["10.1111\/scd.12328"],"URL":"https:\/\/doi.org\/10.1111\/scd.12328","archive":["Portico"],"relation":{},"ISSN":["0275-1879","1754-4505"],"issn-type":[{"value":"0275-1879","type":"print"},{"value":"1754-4505","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,9,12]]},"assertion":[{"value":"2018-03-29","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-07-28","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-09-12","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}