{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T15:25:55Z","timestamp":1773761155961,"version":"3.50.1"},"reference-count":44,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2019,5,3]],"date-time":"2019-05-03T00:00:00Z","timestamp":1556841600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Special Care in Dentistry"],"published-print":{"date-parts":[[2019,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Down syndrome (DS) presents with prevalent diseases in the oral cavity and the need of constant dental care and follow\u2010up. The use of conscious sedation (CS) for dental care in adult DS with behavioral disorders is poorly documented. The aim of this study was to evaluate the effectiveness and safety of CS procedures with oral midazolam using previous psychoprophylaxis sessions in DS adult patients with behavioral disorders. Methods: Twenty\u2010nine DS adults with behavioral disorders. The patients were managed with psychoprophylaxis followed by oral CS using 15 or 30\u00a0mg midazolam. Vital parameters were monitored. The Houpt and Brietkopf and Buttner scales were used. Results: Patients under CS received an initial dose of 15\u00a0mg midazolam; however, 51.72% needed a 30\u00a0mg dose at the following sessions. Results showed that 71.4% treated with the 15\u00a0mg dose had Houpt scale overall behavior scores of 4 or 5, while 93.33% of those receiving 30\u00a0mg had scores of 5 or 6 (chi\u2010square\u00a0=\u00a015.95 <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.01). Conclusion: Psychoprophylaxis sessions followed by CS procedures using oral midazolam in adult DS with behavioral disorders were shown to be a useful strategy to perform routine dental treatment safely. Midazolam produces anterograde amnesia, and participants were more cooperative in the following visits.<\/jats:p>","DOI":"10.1111\/scd.12382","type":"journal-article","created":{"date-parts":[[2019,5,3]],"date-time":"2019-05-03T13:06:15Z","timestamp":1556888775000},"page":"389-398","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Psychoprophylaxis for oral conscious sedation for dental care in Down syndrome adults with behavioral disorder"],"prefix":"10.1111","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7782-6685","authenticated-orcid":false,"given":"Teresita","family":"Ferrary","sequence":"first","affiliation":[{"name":"Department of Internal Medicine (Area Disability) Facultad de Odontolog\u00eda, Universidad de Buenos Aires Buenos Aires, Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noelia","family":"Sanchez 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Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Belen","family":"Benitez","sequence":"additional","affiliation":[{"name":"Department of Pharmacology Facultad de Odontolog\u00eda, Universidad de Buenos Aires Buenos Aires, Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariana","family":"Armada","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine (Area Disability) Facultad de Odontolog\u00eda, Universidad de Buenos Aires Buenos Aires, Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maite","family":"Echaide","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine (Area Disability) Facultad de Odontolog\u00eda, Universidad de Buenos Aires Buenos Aires, Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriela","family":"Scagnet","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine (Area Disability) 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