{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T02:00:28Z","timestamp":1747188028641,"version":"3.40.5"},"reference-count":15,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,1,29]],"date-time":"2020-01-29T00:00:00Z","timestamp":1580256000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Special Care in Dentistry"],"published-print":{"date-parts":[[2020,3]]},"abstract":"Abstract<\/jats:title>Aim<\/jats:title>Orodental manifestations are commonly presented in Wiskott Aldrich Syndrome (WAS). The purpose of this paper is to report a case of dental management of a 5\u2010year\u2010old male child with WAS before Hematopoietic Stem Cell Transplantation (HSCT). Such patients are more prone to infection due to pretransplantation chemotherapy and posttransplantation immunosuppression; thus, it becomes imperative to eliminate all potential sources of infection before transplantation.<\/jats:p><\/jats:sec>Materials and Methods<\/jats:title>Fluctuating blood parameters before the dental procedure was an important challenge in rendering dental treatment. Dental procedures were carried out under general anesthesia by maintaining the hematological parameters with blood and platelet transfusion. The conventional dental treatment may not be applicable in such patients as failure of dental treatment can cause the failure of HSCT, and it has to be modified based on the clinical acumen and recommendations.<\/jats:p><\/jats:sec>Conclusions<\/jats:title>This case report focuses on the measures to be taken before, during, and after the dental procedure to ensure the success of the dental therapy and prevent failure of HSCT due to residual dental foci of infection. A multidisciplinary approach involving a pedodontist, a pediatrician, and a hematologist can improve the quality of life of such patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/scd.12452","type":"journal-article","created":{"date-parts":[[2020,1,29]],"date-time":"2020-01-29T11:28:00Z","timestamp":1580297280000},"page":"206-210","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Dental management of a child with Wiskott Aldrich syndrome prior to bone marrow transplant: A case report"],"prefix":"10.1111","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9593-9488","authenticated-orcid":false,"given":"Anitha","family":"Santosh","sequence":"first","affiliation":[{"name":"Department of Pediatric and Preventive Dentistry Nair Hospital Dental College Mumbai Mahrashtra India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6307-841X","authenticated-orcid":false,"given":"Karun","family":"Banthiya","sequence":"additional","affiliation":[{"name":"Department of Pediatric and Preventive Dentistry Nair Hospital Dental College Mumbai Mahrashtra India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.T.","family":"Deshmukh","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Seth GS Medical College and Hospital Mumbai Mahrashtra India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Prasad","family":"Bhange","sequence":"additional","affiliation":[{"name":"Department of Dentistry Seth GS Medical College and Hospital Mumbai Mahrashtra India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shagun","family":"Shah","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Seth GS Medical College and Hospital Mumbai Mahrashtra India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0363-7731","authenticated-orcid":false,"given":"Adesh","family":"Kakade","sequence":"additional","affiliation":[{"name":"Department of Pediatric and Preventive Dentistry Nair Hospital Dental College Mumbai Mahrashtra India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,1,29]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2009.03.049"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2006.02.005"},{"key":"e_1_2_7_4_1","first-page":"212","article-title":"Familiarer, angeborener morbus werlhofli","volume":"68","author":"Wiskott A","year":"1937","journal-title":"Monatsschrift Kinderheikunde"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.13.2.133"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/nyas.12049"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4362.1985.tb05726.x"},{"issue":"3","key":"e_1_2_7_8_1","first-page":"225","article-title":"Dental considerations in the treatment of Wiskott\u2010Aldrich syndrome: report of case","volume":"56","author":"Boraz RA","year":"1989","journal-title":"ASDC J Dent Child"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bmt.1705429"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1754-4505.2004.tb01707.x"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.21726\/rsbo.v15i2.678"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.15831"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-003-0209-4"},{"key":"e_1_2_7_14_1","first-page":"79","article-title":"Dental treatment of children with severe combined immunodeficiency","volume":"5","author":"Moyer I","year":"1983","journal-title":"Pediatr Dent"},{"key":"e_1_2_7_15_1","first-page":"392","article-title":"Dental management of pediatric patients receiving immunosuppressive therapy and\/or radiation therapy","volume":"40","author":"American Academy of Pediatric Dentistry","year":"2018","journal-title":"Clin Guid Ref Man"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-018-2576-x"}],"container-title":["Special Care in Dentistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fscd.12452","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/scd.12452","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/scd.12452","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/scd.12452","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,7]],"date-time":"2023-09-07T03:35:42Z","timestamp":1694057742000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/scd.12452"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1,29]]},"references-count":15,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2020,3]]}},"alternative-id":["10.1111\/scd.12452"],"URL":"https:\/\/doi.org\/10.1111\/scd.12452","archive":["Portico"],"relation":{},"ISSN":["0275-1879","1754-4505"],"issn-type":[{"type":"print","value":"0275-1879"},{"type":"electronic","value":"1754-4505"}],"subject":[],"published":{"date-parts":[[2020,1,29]]},"assertion":[{"value":"2019-10-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-01-10","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-01-29","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}