{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T23:42:23Z","timestamp":1772754143130,"version":"3.50.1"},"reference-count":21,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2020,5,1]],"date-time":"2020-05-01T00:00:00Z","timestamp":1588291200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Special Care in Dentistry"],"published-print":{"date-parts":[[2020,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Factor X deficiency (known as; Stuart\u2010Prower factor deficiency or F10 deficiency) is a rare inherited bleeding disorder. It affects one per 1 million individuals worldwide. Patients with inherited bleeding disorder reported difficulty in accessing primary dental care either due to their medical diseases or their related barriers.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aim<\/jats:title><jats:p>This article aims to identify barriers to oral health as perceived by the patient with factor X deficiency who had been refused treatment by three dentists. A further aim is to provide dentists with the knowledge required to manage patients diagnosed with factor X deficiency.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and Case Report<\/jats:title><jats:p>A 30\u2010year\u2010old male with the inherited, severe factor X deficiency (&lt;1%) was asked to complete a survey which includes 22 semistructured, validated questions to assess his perceived barriers to dental services. Dental examination revealed that the patient required having nonsurgical periodontal therapy under local anesthesia. The treatment plan was discussed with the patient and his hematologist. The patient's hematologist advised performing dental treatment shortly (ie, 1\u20102\u00a0h) after hematological cover with a prothrombin complex concentrate (1000\u00a0U; Octoplex<jats:sup>\u00ae<\/jats:sup>) via intravenous infusion. The hematologist also prescribed tranexamic acid mouthwash (250\u00a0mg in 5\u00a0mL) and the patient was instructed to rinse his mouth for 3\u20105 min with 500 \u03bcg (10\u00a0mL) in case of bleeding following treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Findings<\/jats:title><jats:p>The patient reported several barriers to dental services such as high anxiety levels regarding oral bleeding, difficulty in finding a suitable dental clinic, high cost of dental treatment, and the need for hematological cover prior to dental treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The proper communication between dentist and hematologist was a vital step to render safe and effective dental care and to reduce the patient's anxiety toward the dentist.<\/jats:p><\/jats:sec>","DOI":"10.1111\/scd.12463","type":"journal-article","created":{"date-parts":[[2020,5,1]],"date-time":"2020-05-01T19:30:02Z","timestamp":1588361402000},"page":"308-314","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["\u201c<i>I have been refused to be treated by three dentists<\/i>\u201d: Barriers to patient care"],"prefix":"10.1111","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3817-3938","authenticated-orcid":false,"given":"Hassan","family":"Abed","sequence":"first","affiliation":[{"name":"Department of Basic and Clinical Oral Sciences Faculty of Dentistry Umm Al\u2010Qura University  Makkah Saudi Arabia"},{"name":"Department of Sedation and Special Care Dentistry Guy's and St. Thomas' NHS Foundation Trust  London United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jameel","family":"Abuljadayel","sequence":"additional","affiliation":[{"name":"Department of Preventive Dentistry Faculty of Dentistry Umm Al\u2010Qura University  Makkah Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,5]]},"reference":[{"key":"e_1_2_12_2_1","unstructured":"National Library of Medicine. Genetics home reference. Factor X deficiency.https:\/\/ghr.nlm.nih.gov\/condition\/factor-x-deficiency#statistics.Accessed February 2 2020."},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0038-1637743"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00031-19"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000010950"},{"key":"e_1_2_12_6_1","first-page":"9657516","article-title":"Inherited moderate factor X deficiency presenting as cardiac tamponade","volume":"2019","author":"Othman T","year":"2019","journal-title":"Case Rep In Hematol"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/MBC.0000000000000787"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.4274\/tjh.2017.0446"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.2864-19"},{"issue":"2","key":"e_1_2_12_10_1","first-page":"249","article-title":"Molecular analysis of the genotype\u2010phenotype relationship in factor X deficiency","volume":"106","author":"Millar DS","year":"2000","journal-title":"Hum Genet"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2516.2011.02716.x"},{"key":"e_1_2_12_12_1","unstructured":"Joanna Briggs Institute. Critical appraisal tools.https:\/\/joannabriggs.org\/ebp\/critical_appraisal_tools. Accessed on February 02 2020."},{"key":"e_1_2_12_13_1","unstructured":"HitchingsEJ The oral health of individuals with haemophilia: a mixed methods investigation New\u2010Zealand University of Otago;2012.https:\/\/ourarchive.otago.ac.nz\/handle\/10523\/2536. Accessed on February 17 2020."},{"key":"e_1_2_12_14_1","unstructured":"University of Otago Library. Oral health of individuals with haemophilia\u2014adult questionnaire 2012.https:\/\/ourarchive.otago.ac.nz\/bitstream\/handle\/10523\/2536\/Appendix7.pdf?sequence=2&isAllowed=y. Accessed on February 7 2020."},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005650-198102000-00001"},{"issue":"6","key":"e_1_2_12_16_1","first-page":"56","article-title":"Dental management of patients with inherited bleeding disorders: a multidisciplinary approach","volume":"65","author":"Abed H","year":"2017","journal-title":"Gen Dentistr"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/scd.12359"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2591.2008.01507.x"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/hae.13695"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bdj.2008.693"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bdj.2008.533"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bdj.2008.457"}],"container-title":["Special Care in Dentistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/scd.12463","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/scd.12463","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/scd.12463","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,6]],"date-time":"2023-09-06T02:57:23Z","timestamp":1693969043000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/scd.12463"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,5]]},"references-count":21,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2020,5]]}},"alternative-id":["10.1111\/scd.12463"],"URL":"https:\/\/doi.org\/10.1111\/scd.12463","archive":["Portico"],"relation":{},"ISSN":["0275-1879","1754-4505"],"issn-type":[{"value":"0275-1879","type":"print"},{"value":"1754-4505","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,5]]},"assertion":[{"value":"2020-01-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-04-12","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-05-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}