{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T17:06:29Z","timestamp":1780592789289,"version":"3.54.1"},"reference-count":17,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2020,5,22]],"date-time":"2020-05-22T00:00:00Z","timestamp":1590105600000},"content-version":"vor","delay-in-days":21,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Special Care in Dentistry"],"published-print":{"date-parts":[[2020,5]]},"abstract":"Abstract<\/jats:title>Aim<\/jats:title>Tongue bites frequently occur during seizures in epilepsy patients. We report two cases of cognitively impaired Lennox\u2010Gastaut syndrome patients with reactive lesions on the tongues.<\/jats:p><\/jats:sec>Case presentations<\/jats:title>Case 1 was a 30\u2010year\u2010old man whose chief complaint was mouth pain. Local finding was a small bean\u2010sized pedunculated mass on the tongue, histopathologically diagnosed as inflammatory fibrous hyperplasia. Case 2 was a 45\u2010year\u2010old man whose chief complaint was bleeding from the mouth. His clinical finding was blood loss anemia. Local finding was a 20\u2010mm\u2010diameter pedunculated mass on the tongue, histopathologically diagnosed as pyogenic granuloma.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>These mass lesions were believed to be reactive, caused by repetitive minor damage involving reparative fibrous tissue response. Therefore, the two cases may have involved reparative responses to mucosal injury incurred by accidental bites during epileptic seizures. Intellectual disability made medical treatment difficult and had allowed the massive lesions to form. It is necessary for cognitively impaired epilepsy patients to undergo regular dental examinations in order to get used to dental checks and to increase the number of intraoral observations in the context of close cooperation between dentists and epilepsy therapists.<\/jats:p><\/jats:sec>","DOI":"10.1111\/scd.12470","type":"journal-article","created":{"date-parts":[[2020,5,22]],"date-time":"2020-05-22T15:35:33Z","timestamp":1590161733000},"page":"285-290","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Reactive bite\u2010related tongue lesions in cognitively impaired epilepsy patients: A report of two cases"],"prefix":"10.1111","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2242-1968","authenticated-orcid":false,"given":"Yutaka","family":"Fukumoto","sequence":"first","affiliation":[{"name":"Department of Dentistry National Center Hospital of Neurology and Psychiatry Kodaira Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takeshi","family":"Miyama","sequence":"additional","affiliation":[{"name":"Department of Surgery National Center Hospital of Neurology and Psychiatry Kodaira Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zen\u2010ichi","family":"Tanei","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine National Center Hospital of Neurology and Psychiatry Kodaira Japan"},{"name":"Department of Neuropathology Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuko","family":"Saito","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine National Center Hospital of Neurology and Psychiatry Kodaira Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshihide","family":"Ota","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery Tokai University School of Medicine Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,5,22]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0013-9580.2005.66104.x"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1157.1997.tb01733.x"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(08)70292-8"},{"key":"e_1_2_7_5_1","first-page":"183","article-title":"Lennox\u2010Gastaut syndrome: a consensus approach to differential diagnosis","volume":"3","author":"Bourgeois BFD","year":"2014","journal-title":"Epilepsia"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.1985.0107"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1167.2008.01554.x"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yebeh.2012.06.020"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1059-1311(96)80032-X"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1754-4505.2007.tb00339.x"},{"key":"e_1_2_7_11_1","first-page":"251","article-title":"Reactive lesions of the oral cavity: a retrospective study on 2068 cases","volume":"9","author":"Naderi NJ","year":"2012","journal-title":"Dent Res J"},{"key":"e_1_2_7_12_1","volume-title":"Oral and Maxillofacial Pathology: A Rationale for Diagnosis and Treatment","author":"Robert EM","year":"2012"},{"key":"e_1_2_7_13_1","first-page":"473","volume-title":"Oral and Maxillofacial Pathology","author":"Neville BW","year":"2016"},{"key":"e_1_2_7_14_1","first-page":"207","article-title":"Pyogenic granuloma of the tongue. Report of two cases","volume":"18","author":"Yamaoka Y","year":"1977","journal-title":"Bull Tokyo Dent Coll"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.3950\/jibiinkoka.94.12_1857"},{"key":"e_1_2_7_16_1","first-page":"391","article-title":"Pyogenic granuloma \u2013 clinical features, incidence, histology, and result of treatment: report of 242 cases","volume":"24","author":"Bhaskar SN","year":"1966","journal-title":"J Oral Surg"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40780-017-0088-5"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(51)90432-X"}],"container-title":["Special Care in Dentistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fscd.12470","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/scd.12470","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/scd.12470","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/scd.12470","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,6]],"date-time":"2023-09-06T02:57:07Z","timestamp":1693969027000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/scd.12470"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,5]]},"references-count":17,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2020,5]]}},"alternative-id":["10.1111\/scd.12470"],"URL":"https:\/\/doi.org\/10.1111\/scd.12470","archive":["Portico"],"relation":{},"ISSN":["0275-1879","1754-4505"],"issn-type":[{"value":"0275-1879","type":"print"},{"value":"1754-4505","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,5]]},"assertion":[{"value":"2020-01-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-04-22","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-05-22","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}