{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T17:21:14Z","timestamp":1791652874315,"version":"4.3.4"},"reference-count":13,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2020,9,2]],"date-time":"2020-09-02T00:00:00Z","timestamp":1599004800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Special Care in Dentistry"],"published-print":{"date-parts":[[2020,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To present early teeth extractions as a treatment option in severe dental crowding in patients with generalized recessive dystrophic epidermolysis bullosa (RDEB).<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and methods<\/jats:title><jats:p>Three patients with generalized RDEB were treated with early teeth extractions to prevent severe dental crowding.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Two patients had bilateral upper first premolars extraction, and the third patient had permanent maxillary canine extraction. Crowding was avoided, and no further orthodontic treatment was necessary.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Considering the challenges of severe mucosal fragility and microstomia in patients with generalized RDEB, early teeth extractions are a reasonable option as an orthodontic management. This approach reduces the severity of dental crowding as the child gets older and reduces the need for orthodontic appliances. Individual factors such as access to dental care, general health, and oral health have an important impact on the decision\u2010making process. Orthodontic treatment planning should include a multidisciplinary team.<\/jats:p><\/jats:sec>","DOI":"10.1111\/scd.12515","type":"journal-article","created":{"date-parts":[[2020,9,2]],"date-time":"2020-09-02T20:33:38Z","timestamp":1599078818000},"page":"561-565","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Early teeth extraction in patients with generalized recessive dystrophic epidermolysis bullosa: A case series"],"prefix":"10.1111","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1893-3007","authenticated-orcid":false,"given":"Sebasti\u00e1n","family":"V\u00e9liz","sequence":"first","affiliation":[{"name":"Faculty of Dentistry Universidad of Chile Santiago Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hinrich","family":"Huber","sequence":"additional","affiliation":[{"name":"Faculty of Dentistry Universidad of Chile Santiago Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda Joao","family":"Yubero","sequence":"additional","affiliation":[{"name":"DEBRA Chile Foundation Santiago Chile"},{"name":"Faculty of Medicine Cl\u00ednica Alemana Universidad del Desarrollo Santiago Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ignacia","family":"Fuentes","sequence":"additional","affiliation":[{"name":"DEBRA Chile Foundation Santiago Chile"},{"name":"Research Scientist, Genetics and Genomic Center, Facultad de Medicina Cl\u00ednica Alemana Universidad del Desarrollo Santiago Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatimah","family":"Alsayer","sequence":"additional","affiliation":[{"name":"Honorary Clinical Senior Lecturer, Royal National ENT and Eastman Dental Hospitals University College London Hospitals London United 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