{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T14:49:04Z","timestamp":1787064544184,"version":"build-2736575974"},"reference-count":15,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2020,9,3]],"date-time":"2020-09-03T00:00:00Z","timestamp":1599091200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Special Care in Dentistry"],"published-print":{"date-parts":[[2020,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Vesiculobullous and macular lesions in the oral mucosa have been reported in patients positive for SARS\u2010CoV\u20102 infection. Nonetheless, the significance and physiopathology of oral manifestations have not been clearly established in the clinical progression or outcome of the infection.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To describe the clinico\u2010pathological oral mucosal lesions in four patients with confirmed SARS\u2010CoV\u20102 infection.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and Results<\/jats:title>\n                    <jats:p>Four patients with COVID\u201019 disease and confirmed by polymerase chain reaction (PCR) presented angina bullosa hemorragica\u2010like lesion, vascular disorder, and nonspecific stomatitis, one patient with histological analysis demonstrated perivascular reactive lymphocitic infliltrate, focal capillary thrombosis, and hemorrhage. According to the discrimination of other local and systemic conditions and the synchronous onset of oral and systemic symptoms, the diagnosis of oral lesions probably associated with COVID\u201019 was established.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Infection with SARS\u2010CoV\u20102 may result in oral manifestations with various clinical presentations, which presumably support the hypothesis of thrombi formation and vasculitis; nevertheless, these findings need more evidence and a long\u2010term follow up of patients to accurately establish the significance of the oral mucosa affection in the COVID\u201019 disease.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/scd.12520","type":"journal-article","created":{"date-parts":[[2020,9,3]],"date-time":"2020-09-03T16:53:56Z","timestamp":1599152036000},"page":"555-560","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":81,"title":["Oral mucosal lesions in patients with SARS\u2010CoV\u20102 infection. Report of four cases. Are they a true sign of COVID\u201019 disease?"],"prefix":"10.1111","volume":"40","author":[{"given":"Roberto Onner","family":"Cruz Tapia","sequence":"first","affiliation":[{"name":"Department of Oral and Maxillofacial Pathology, Postgraduate and Research Division Universidad Nacional Aut\u00f3noma de M\u00e9xico  Mexico City Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto Jose","family":"Peraza Labrador","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Pathology Universidad El Bosque  Bogota Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Douglas Magno","family":"Guimaraes","sequence":"additional","affiliation":[{"name":"School of Dentistry Centro Universitario do Estado do Para  Belem Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5522-3186","authenticated-orcid":false,"given":"Luciano Hermios","family":"Matos Valdez","sequence":"additional","affiliation":[{"name":"Faculty of Dentistry, Postgraduate Unit Universidad Nacional Mayor de San Marcos  Lima Peru"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,9,3]]},"reference":[{"key":"e_1_2_7_2_1","unstructured":"Worldmeter [Homepage on the internet] COVID\u201019 Coronavirus Pandemic. Available from:https:\/\/www.worldometers.info\/coronavirus\/. (Accessed July 29 2020)."},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2020.03.041"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.2648"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaut.2020.102433"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.16387"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.19163"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1051\/mbcb\/2020011"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/odi.13532"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41368-020-0074-x"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41368-020-0080-z"},{"issue":"4","key":"e_1_2_7_12_1","first-page":"e563","article-title":"Oral lesions in a patient with COVID\u201019","volume":"25","author":"Soares CD","year":"2020","journal-title":"Med Oral Patol Oral Cir Bucal"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2020.06.012"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdermsci.2020.04.007"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.trsl.2020.04.007"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1136\/jclinpath-2020-206635"}],"container-title":["Special Care in Dentistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/scd.12520","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/scd.12520","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/scd.12520","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,4]],"date-time":"2023-09-04T00:55:41Z","timestamp":1693788941000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/scd.12520"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9,3]]},"references-count":15,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2020,11]]}},"alternative-id":["10.1111\/scd.12520"],"URL":"https:\/\/doi.org\/10.1111\/scd.12520","archive":["Portico"],"relation":{},"ISSN":["0275-1879","1754-4505"],"issn-type":[{"value":"0275-1879","type":"print"},{"value":"1754-4505","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,9,3]]},"assertion":[{"value":"2020-07-09","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-08-19","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-09-03","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}