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Classical treatment modalities are based on the use of corticosteroids, immune\u2010modulators and more recently, biologics. Ustekinumab is a novel agent from this last group that has shown efficacy in a limited number of case reports. A case of a debilitating CD presenting initially with oral manifestations and ultimately managed with ustekinumab is reported.<\/jats:p>","DOI":"10.1111\/scd.12598","type":"journal-article","created":{"date-parts":[[2021,4,27]],"date-time":"2021-04-27T20:52:17Z","timestamp":1619556737000},"page":"634-638","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Crohn's disease initially presenting with oral manifestations and managed with ustekinumab: A case report"],"prefix":"10.1111","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2512-1557","authenticated-orcid":false,"given":"Mohammad S.","family":"Alrashdan","sequence":"first","affiliation":[{"name":"Department of Oral Medicine and Oral Surgery, Faculty of Dentistry Jordan University of Science and Technology  Irbid Jordan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rima A.","family":"Safadi","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine and Oral Surgery, Faculty of Dentistry Jordan University of Science and Technology  Irbid Jordan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,4,27]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-0825.2011.01811.x"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.crohns.2009.12.002"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ibd.20983"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bdj.2016.954"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bdj.2017.884"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1533-2500.2007.00124.x"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otc.2010.09.007"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.2011.300420"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2004.01.063"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra0804647"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1080\/00016480310015326"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgh.13866"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otc.2010.09.006"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-0825.2008.01500.x"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-0825.2005.01143.x"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/983902"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2018.3631"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12876-018-0818-7"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1177\/1756284820934327"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1093\/ibd\/izz321"}],"container-title":["Special Care in Dentistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/scd.12598","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/scd.12598","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/scd.12598","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,29]],"date-time":"2023-08-29T08:52:43Z","timestamp":1693299163000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/scd.12598"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4,27]]},"references-count":20,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2021,9]]}},"alternative-id":["10.1111\/scd.12598"],"URL":"https:\/\/doi.org\/10.1111\/scd.12598","archive":["Portico"],"relation":{},"ISSN":["0275-1879","1754-4505"],"issn-type":[{"value":"0275-1879","type":"print"},{"value":"1754-4505","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,4,27]]},"assertion":[{"value":"2020-11-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-04-13","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-04-27","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}