{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T02:00:51Z","timestamp":1747188051148,"version":"3.40.5"},"reference-count":18,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2021,9,30]],"date-time":"2021-09-30T00:00:00Z","timestamp":1632960000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Special Care in Dentistry"],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>The purpose of this study was to describe a detailed investigation of craniofacial and dental characteristics in a group of Brazilian Rubinstein\u2013Taybi syndrome (RSTS) patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and results<\/jats:title><jats:p>Thirteen RSTS patients treated in a special care dental clinic after 10 years were studied. Panoramic radiographs were obtained from all patients, and cephalometric analysis was performed in eight patients. Five male and eight white female patients with a median age of 11.7 years were analyzed. All the RSTS patients were mouth breathers and presented malocclusion, transverse hypoplastic maxilla, nine subjects (9\/13; 69.2%) had posterior crossbite, and eight (61.53%) exhibited talon cusps. Most patients presented class II skeletal pattern and were brachycephalic. Regarding systemic disorders, one patient (7.69%) reported seizure episodes during childhood, and four patients (30.76%) presented heart valve disorders. All patients presented reduced attention span, low intolerance to dental interventions, impulsiveness, and irritability.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Since RSTS exhibits oral and skeletal changes, early dental treatment is essential for these patients. Dentists must be aware of medical problems related to heart disease and persist in conditioning techniques to obtain cooperation and avoid dental care under general anesthesia.<\/jats:p><\/jats:sec>","DOI":"10.1111\/scd.12645","type":"journal-article","created":{"date-parts":[[2021,9,30]],"date-time":"2021-09-30T08:53:24Z","timestamp":1632992004000},"page":"143-148","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Oral and cephalometric study in Brazilian Rubinstein\u2013Taybi syndrome patients"],"prefix":"10.1111","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4352-7959","authenticated-orcid":false,"given":"Fabiana","family":"Martins","sequence":"first","affiliation":[{"name":"Special Care Dentistry Center School of Dentistry University of S\u00e3o Paulo S\u00e3o Paulo Brazil"},{"name":"School of Dentistry University of Santo Amaro S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Clelia","family":"Roussen","sequence":"additional","affiliation":[{"name":"Special Care Dentistry Center School of Dentistry University of S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nathalie","family":"Rezende","sequence":"additional","affiliation":[{"name":"Special Care Dentistry Center School of Dentistry University of S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cybelle","family":"Hiraoka","sequence":"additional","affiliation":[{"name":"Special Care Dentistry Center School of Dentistry University of S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcelo","family":"Zamunaro","sequence":"additional","affiliation":[{"name":"Special Care Dentistry Center School of Dentistry University of S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marina","family":"Gallottini","sequence":"additional","affiliation":[{"name":"Special Care Dentistry Center School of Dentistry University of S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,9,30]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ejhg.5201594"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.61883"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/genes12070968"},{"key":"e_1_2_8_5_1","unstructured":"Association BR\u2010TS \u2010 Statistics. Available from:http:\/\/www.aRSTSbrasil.org.br\/. Accessed July 18 2021."},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1080\/08880018.2021.1928802"},{"issue":"5","key":"e_1_2_8_7_1","first-page":"ZJ05","article-title":"Broad Thumb\u2010Hallux syndrome: a diagnosis made on clinical findings","volume":"11","author":"Deepthi DA","year":"2017","journal-title":"J Clin Diagn Res"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320370607"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0528.2005.00259.x"},{"volume-title":"Malocclusion of the Teeth","year":"1907","author":"Angle EH","key":"e_1_2_8_10_1"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.2319\/041513-291.1"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejo\/cjp031"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.5056\/jnm20025"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.106.183095"},{"issue":"4","key":"e_1_2_8_15_1","first-page":"434","article-title":"An evaluation of the iatrosedative process for treating dental fear","volume":"19","author":"Friedman N","year":"1998","journal-title":"Compend Contin Educ Dent"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12903-019-0991-2"},{"issue":"1","key":"e_1_2_8_17_1","first-page":"33","article-title":"A cephalometric study in Rubinstein\u2010Taybi syndrome","volume":"11","author":"Hennekam RC","year":"1991","journal-title":"J Craniofac Genet Dev Biol"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1808-8694(15)31304-5"},{"issue":"3","key":"e_1_2_8_19_1","doi-asserted-by":"crossref","first-page":"220","DOI":"10.61872\/sdj-2021-03-727","article-title":"Orthodontic treatment of patients with special needs in Switzerland","volume":"131","author":"Antonarakis GS","year":"2021","journal-title":"Swiss Dent J"}],"container-title":["Special Care in Dentistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/scd.12645","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/scd.12645","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/scd.12645","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,9]],"date-time":"2024-09-09T02:03:56Z","timestamp":1725847436000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/scd.12645"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9,30]]},"references-count":18,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,3]]}},"alternative-id":["10.1111\/scd.12645"],"URL":"https:\/\/doi.org\/10.1111\/scd.12645","archive":["Portico"],"relation":{},"ISSN":["0275-1879","1754-4505"],"issn-type":[{"type":"print","value":"0275-1879"},{"type":"electronic","value":"1754-4505"}],"subject":[],"published":{"date-parts":[[2021,9,30]]},"assertion":[{"value":"2021-07-17","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-08-17","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-09-30","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}