{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T21:27:58Z","timestamp":1777498078718,"version":"3.51.4"},"reference-count":47,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,11,18]],"date-time":"2021-11-18T00:00:00Z","timestamp":1637193600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Special Care in Dentistry"],"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims<\/jats:title><jats:p>Multisystemic inflammatory syndrome in children (MIS\u2010C) is a condition noted in some children asymptomatic but positive to Sars\u2010cov\u20102 antibody and it presents clinical and laboratory changes similar to Kawasaki disease (KD). Oral changes have also been observed. This systematic review evaluated oral manifestations detected in children with MIS\u2010C and KD associated to COVID\u201019.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and Results<\/jats:title><jats:p>This work was registered at PROSPERO (#CRD42020225909), following PRISMA guidelines. A comprehensive research was conducted in MEDLINE, Web of Science, EMBASE, LILACS, Scopus, and Grey Literature through August 2021, based on original research evaluating children diagnosed with MIS\u2010C or KD related to COVID\u201019. Two authors independently screened all retrieved references. Twenty five selected studies evaluated 624 children, mean age 8.78 years. The assessment of the risk of bias (ROB) showed that most of them presented low ROB. Oral manifestations were erythematous mucous membrane, oral ulcers lesions, dry, swollen and cracked lips, and strawberry tongue.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>MIS\u2010C and KD share the same oral manifestations and their identification may lead to an early diagnosis.<\/jats:p><\/jats:sec>","DOI":"10.1111\/scd.12669","type":"journal-article","created":{"date-parts":[[2021,11,18]],"date-time":"2021-11-18T15:51:15Z","timestamp":1637250675000},"page":"266-280","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Oral manifestations of multisystemic inflammatory syndrome in children (MIS\u2010C) and Kawasaki disease associated to COVID\u201019: A systematic review"],"prefix":"10.1111","volume":"42","author":[{"given":"Rebeca Barros","family":"Nascimento","sequence":"first","affiliation":[{"name":"Post\u2010graduate Program in Dentistry and Health School of Dentistry, Federal 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