{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T04:34:14Z","timestamp":1791952454307,"version":"4.3.4"},"reference-count":33,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2021,11,22]],"date-time":"2021-11-22T00:00:00Z","timestamp":1637539200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Special Care in Dentistry"],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>To describe oral manifestations in children born with microcephaly attributed to congenital Zika virus syndrome (CZS).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Data was collected in semiannual intervals from 2017 to 2019, by oral exams of the children and interview with caregivers at a Public Dental Center in Rio de Janeiro, Brazil. A single calibrated examiner performed clinical examinations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of 38 eligible children, 34 were followed\u2010up from 12 to 30 months of age, 20 boys and 14 girls. The mean age of emergence of their first primary tooth was 12.4 months (SD = 2.9). By 30 months of age only 14.7% (\n                      <jats:italic>n<\/jats:italic>\n                      = 5) had complete primary dentition. Alteration in the sequence of tooth emergence was observed in 41.1% (\n                      <jats:italic>n<\/jats:italic>\n                      = 14). Radiographic examination demonstrated dental agenesis (14.7%\n                      <jats:italic>n<\/jats:italic>\n                      = 5). Dental developmental alterations (38.2%, n = 13), enamel defects (14.7%,\n                      <jats:italic>n<\/jats:italic>\n                      = 5), eruption cysts\/hematoma (23.5%,\n                      <jats:italic>n<\/jats:italic>\n                      = 8), gingival bleeding (55.8%,\n                      <jats:italic>n<\/jats:italic>\n                      = 19), narrow palate, and bruxism (64.7%,\n                      <jats:italic>n<\/jats:italic>\n                      = 22) were also observed. No child had dental caries.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Children with microcephaly attributed to CZS presented oral manifestations early in life.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/scd.12681","type":"journal-article","created":{"date-parts":[[2021,11,22]],"date-time":"2021-11-22T23:45:58Z","timestamp":1637624758000},"page":"343-351","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Oral manifestations of congenital Zika virus infection in children with microcephaly: 18\u2010month follow\u2010up case series"],"prefix":"10.1111","volume":"42","author":[{"given":"D\u00e9bora Teixeira","family":"Medina","sequence":"first","affiliation":[{"name":"Rio de Janeiro State University \u2010 UERJ School of Dentistry Department of Community and Preventive Dentistry  Rio de Janeiro Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5688-4747","authenticated-orcid":false,"given":"Ana Paula Pires dos","family":"Santos","sequence":"additional","affiliation":[{"name":"Rio de Janeiro State University \u2010 UERJ School of Dentistry Department of Community and Preventive Dentistry  Rio de Janeiro Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernanda Moraes Daniel Fialho","family":"Rodrigues","sequence":"additional","affiliation":[{"name":"Instituto Estadual do C\u00e9rebro Paulo Niemeyer  Rio de Janeiro Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Branca Heloisa de","family":"Oliveira","sequence":"additional","affiliation":[{"name":"Rio de Janeiro State University \u2010 UERJ School of Dentistry Department of Community and Preventive Dentistry  Rio de Janeiro Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,11,22]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.15831"},{"key":"e_1_2_10_3_1","unstructured":"World Health Organization. Screening assessment and management of neonates and infants with complications associated with Zika virus exposure in utero. World Health Organization.2016.http:\/\/apps.who.int\/iris\/bitstream\/handle\/10665\/204475\/WHO_ZIKV_MOC_16.3_eng.pdf?sequence=1Accessed March 9 2018."},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph15091990"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/ipd.12402"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-4642(20)30041-9"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/adj.12039"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1984.55.1.19"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.meegid.2019.01.023"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/bdrc.21075"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.4103\/0976-237X.214553"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1590\/1678\u20107757\u20102018\u20100276"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/odi.13238"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.archoralbio.2019.104598"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oooo.2020.02.019"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(14)60932-6"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.1974.0484"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.17796\/jcpd.29.4.jl0510371q155847"},{"key":"e_1_2_10_19_1","volume-title":"Oral and Maxillofacial Pathology","author":"Neville BW","year":"2016"},{"key":"e_1_2_10_20_1","unstructured":"Commission on Oral Health Research & Epidemiology. A review of the developmental defects of enamel index (DDE Index). Report of an FDI Working Group 1992;42:411\u2013426."},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0528.2007.00347.x"},{"issue":"5","key":"e_1_2_10_22_1","first-page":"269","article-title":"Birkhed D. Oral hygiene in relation to caries development and immigrant status in infants and toddlers","volume":"102","author":"Wendt LK","year":"1994","journal-title":"Scand J Dent Res"},{"key":"e_1_2_10_23_1","unstructured":"National Human Genome Research Institute. Human Malformation Terminology. Available athttps:\/\/elementsofmorphology.nih.gov\/index.cgi?tid=70a0a128965515c4. Accessed March 9 2018."},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.5005\/jp-journals-10005-1143"},{"key":"e_1_2_10_25_1","unstructured":"Minist\u00e9rio da Sa\u00fade do Brasil. Diretrizes de estimula\u00e7\u00e3o precoce. 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