{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T20:50:46Z","timestamp":1793307046009,"version":"4.5.0"},"reference-count":48,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2022,1,10]],"date-time":"2022-01-10T00:00:00Z","timestamp":1641772800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Special Care in Dentistry"],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Parental caregivers of children with Down Syndrome (DS) have a greater burden of daily activities that may affect their health. The aim of this exploratory study was to evaluate the impact of caregiving of children with Down syndrome on parenting quality of life, stress, mental and oral health.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Fifty\u2010four parental caregivers of children with DS and 51 parents of children without physical or mental disabilities participated of this study. All participants were clinically examined to evaluate the presence of dental caries, gingival conditions and answered a sociodemographic questionnaire. Depression, anxiety, quality of life and coping strategies were assessed using specific instruments. Hair cortisol level was assessed as biological marker of chronic stress.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Psychological and quality of life parameters were similar between the groups of caregivers (<jats:italic>p<\/jats:italic>\u00a0&gt;\u00a0.05). Caregivers of children with DS were older (48.6\u00a0vs. 41.5, <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.001), had longer caregiving period (&gt;\u00a010 vs\u00a0&lt;\u00a010 years, p\u00a0=\u00a0.003), presented higher gingival bleeding index (6.1\u00a0vs. 4.7, <jats:italic>p<\/jats:italic>\u00a0=\u00a0.014) and higher cortisol levels (55.9\u00a0vs. 38.4, <jats:italic>p<\/jats:italic>\u00a0=\u00a0.07) as compared with parents of children without disabilities. Sociodemographic data has no influence on cortisol levels (<jats:italic>p<\/jats:italic>\u00a0&gt;\u00a0.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>These findings suggest that the caregiving of children with DS has an impact on parenting oral health and stress.<\/jats:p><\/jats:sec>","DOI":"10.1111\/scd.12694","type":"journal-article","created":{"date-parts":[[2022,1,11]],"date-time":"2022-01-11T07:51:25Z","timestamp":1641887485000},"page":"398-403","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Caregiving of children with Down syndrome: impact on quality of life, stress, mental and oral health"],"prefix":"10.1111","volume":"42","author":[{"given":"Caroline","family":"Dias","sequence":"first","affiliation":[{"name":"Department of Preventive and Social Dentistry, Faculty of Dentistry Universidade Federal do Rio Grande do Sul  Porto Alegre Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolina","family":"Schwertner","sequence":"additional","affiliation":[{"name":"Department of Preventive and Social Dentistry, Faculty of Dentistry Universidade Federal do Rio Grande do Sul  Porto Alegre Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D\u00e9bora","family":"Grando","sequence":"additional","affiliation":[{"name":"Department of Preventive and Social Dentistry, Faculty of Dentistry Universidade Federal do Rio Grande do Sul  Porto Alegre Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Augusto Bacelo","family":"Bidinotto","sequence":"additional","affiliation":[{"name":"Department of Preventive and Social Dentistry, Faculty of Dentistry Universidade Federal do Rio Grande do Sul  Porto Alegre Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juliana Balbinot","family":"Hilgert","sequence":"additional","affiliation":[{"name":"Department of Preventive and Social Dentistry, Faculty of Dentistry Universidade Federal do Rio Grande do Sul  Porto Alegre Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaqueline Bohrer","family":"Schuch","sequence":"additional","affiliation":[{"name":"Service of Addiction Psychiatry Hospital de Cl\u00ednicas de Porto Alegre  Porto Alegre Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucas Ara\u00fajo","family":"de Azeredo","sequence":"additional","affiliation":[{"name":"School of Medicine, Graduate Program of Medicine, Neurosciences Pontificia Universidade Cat\u00f3lica do Rio Grande do Sul  Porto Alegre Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mois\u00e9s Evandro","family":"Bauer","sequence":"additional","affiliation":[{"name":"Laboratory of Immunobiology, School of Health and Biological Sciences Pontificia Universidade Cat\u00f3lica do Rio Grande do Sul  Porto Alegre Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5477-2768","authenticated-orcid":false,"given":"Lina Naomi","family":"Hashizume","sequence":"additional","affiliation":[{"name":"Department of Preventive and Social Dentistry, Faculty of Dentistry Universidade Federal do Rio Grande do Sul  Porto Alegre Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,1,10]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1352\/1934-9556-47.6.425"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11013-013-9323-1"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10803-012-1693-7"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/jar.12353"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1080\/09638237.2016.1276538"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/scd.12617"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.22130"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.PSY.0000074759.71084.AB"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1741-2358.2007.00188.x"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12903-018-0500-z"},{"issue":"1","key":"e_1_2_8_12_1","first-page":"30","article-title":"The evaluation of anxiety, parental attitude and coping strategy in parents of children with mental retardation","volume":"11","author":"Keskin G","year":"2010","journal-title":"Anatolian J Psychiat"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.5455\/msm.2016.28.437-439"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1177\/1744629512472610"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/scd.12222"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.18553\/jmcp.2017.23.7.761"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016356408993968"},{"key":"e_1_2_8_18_1","volume-title":"Oral Health Surveys: Basic Methods","author":"World Health Organization","year":"2013"},{"issue":"4","key":"e_1_2_8_19_1","first-page":"355","article-title":"Oral health status and salivary levels of mutans streptococci in children with Down syndrome","volume":"37","author":"Moreira MJ","year":"2015","journal-title":"Pediatr Dent"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/ipd.12168"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0277-9536(98)00009-4"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291798006667"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1037\/0022-006X.56.6.893"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.3109\/00952990.2012.694538"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psyneuen.2016.08.027"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psyneuen.2008.08.024"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0047-6374(03)00148-9"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.11606\/issn.2317-0190.v22i4a122342"},{"key":"e_1_2_8_29_1","first-page":"159","article-title":"Burden assessment, psychiatric morbidity, and their correlates in caregivers of patients with intellectual disability","volume":"25","author":"Bhatia MS","year":"2015","journal-title":"East Asian Arch Psychiatry"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.3109\/02699052.2012.655363"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.soncn.2010.08.005"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1093\/geronj\/45.5.P192"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2788.2010.01332.x"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1093\/geronb\/57.5.P453"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1037\/0033-2909.129.6.946"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1177\/0894318411409420"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1008910527481"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.1111\/hsc.12393"},{"key":"e_1_2_8_39_1","doi-asserted-by":"publisher","DOI":"10.1002\/gps.3853"},{"key":"e_1_2_8_40_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2788.2006.00796.x"},{"key":"e_1_2_8_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0277-9536(00)00365-8"},{"key":"e_1_2_8_42_1","doi-asserted-by":"publisher","DOI":"10.3104\/case-studies.101"},{"key":"e_1_2_8_43_1","doi-asserted-by":"publisher","DOI":"10.1300\/J074v17n01_09"},{"key":"e_1_2_8_44_1","doi-asserted-by":"publisher","DOI":"10.1037\/0882-7974.18.2.250"},{"key":"e_1_2_8_45_1","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.bp.112.125369"},{"key":"e_1_2_8_46_1","doi-asserted-by":"publisher","DOI":"10.1177\/1742395313506947"},{"key":"e_1_2_8_47_1","doi-asserted-by":"publisher","DOI":"10.1352\/1944-7558-116.6.479"},{"key":"e_1_2_8_48_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2788.2007.01012.x"},{"key":"e_1_2_8_49_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2788.2011.01501.x"}],"container-title":["Special Care in Dentistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/scd.12694","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/scd.12694","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/scd.12694","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,24]],"date-time":"2023-08-24T03:57:04Z","timestamp":1692849424000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/scd.12694"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1,10]]},"references-count":48,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2022,7]]}},"alternative-id":["10.1111\/scd.12694"],"URL":"https:\/\/doi.org\/10.1111\/scd.12694","archive":["Portico"],"relation":{},"ISSN":["0275-1879","1754-4505"],"issn-type":[{"value":"0275-1879","type":"print"},{"value":"1754-4505","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,1,10]]},"assertion":[{"value":"2021-08-31","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-12-23","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-01-10","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}