{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,20]],"date-time":"2023-11-20T12:56:27Z","timestamp":1700484987918},"reference-count":26,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2022,5,10]],"date-time":"2022-05-10T00:00:00Z","timestamp":1652140800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Special Care in Dentistry"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>MYH9 disease is a rare genetic disorder in which there is a mutation in the gene for the non\u2010muscle myosin heavy chain IIA. It initially causes macrothrombocytopenia followed by other clinical manifestations. When the patient reaches adulthood, he can develop chronic kidney failure. Thus, the risk of suffering a hemorrhage, difficulty in repairing and, infections increases in individuals with this disease. In addition, the use of drugs in these patients should be carefully evaluated. An adult patient sought dental care with a complaint associated with a tooth with advanced dental caries. He had severe thrombocytopenia (7000 platelets\/mm<jats:sup>3<\/jats:sup>), hearing loss, and chronic kidney failure. The diagnosis of MYH9 disease was confirmed through genotyping. After clinical examination, extraction was planned. Local and systemic procedures were used to prevent hemorrhage, especially postoperatively. Although the patient had an infection at the surgical wound site and no episode of postoperative bleeding, the repair process occurred normally. The purpose of this article is to report the surgical management of a patient with MYH9 disease.<\/jats:p>","DOI":"10.1111\/scd.12727","type":"journal-article","created":{"date-parts":[[2022,5,10]],"date-time":"2022-05-10T20:09:47Z","timestamp":1652213387000},"page":"651-656","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["The surgical management of a patient with chronic renal failure and macrothrombocytopenia related to the MYH9 gene mutation: A case report"],"prefix":"10.1111","volume":"42","author":[{"given":"Rafael Fiorese","family":"Costa","sequence":"first","affiliation":[{"name":"Department of Stomatology, Universidade Federal do Paran\u00e1  Curitiba PR Brazil"},{"name":"Funda\u00e7\u00e3o de Amparo a Pesquisa em Enfermidades Renais e Metab\u00f3licas Pr\u00f3\u2010Renal  Curitiba PR Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S\u00e9rgio Gardano Elias","family":"Bucharles","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o de Amparo a Pesquisa em Enfermidades Renais e Metab\u00f3licas Pr\u00f3\u2010Renal  Curitiba PR Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Douglas Eiji","family":"Kagueiama","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o de Amparo a Pesquisa em Enfermidades Renais e Metab\u00f3licas Pr\u00f3\u2010Renal  Curitiba PR Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cintia Pereira","family":"Kus","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o de Amparo a Pesquisa em Enfermidades Renais e Metab\u00f3licas Pr\u00f3\u2010Renal  Curitiba PR Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ariane de Almeida","family":"Andrade","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o de Amparo a Pesquisa em Enfermidades Renais e Metab\u00f3licas Pr\u00f3\u2010Renal  Curitiba PR Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Acir Jos\u00e9","family":"Dirschnabel","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o de Amparo a Pesquisa em Enfermidades Renais e Metab\u00f3licas Pr\u00f3\u2010Renal  Curitiba PR Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melissa Rodrigues","family":"de Araujo","sequence":"additional","affiliation":[{"name":"Department of Stomatology, Universidade Federal do Paran\u00e1  Curitiba PR Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio Adilson Soares","family":"de Lima","sequence":"additional","affiliation":[{"name":"Department of Stomatology, Universidade Federal do Paran\u00e1  Curitiba PR Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,5,10]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/79069"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.4103\/1319-2442.292323"},{"key":"e_1_2_4_4_1","unstructured":"UntanuRV VajpayeeN.May Hegglin Anomaly. 2021 Jul 21. 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