{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,23]],"date-time":"2025-05-23T12:07:45Z","timestamp":1748002065405,"version":"3.40.5"},"reference-count":25,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2022,9,20]],"date-time":"2022-09-20T00:00:00Z","timestamp":1663632000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Special Care in Dentistry"],"published-print":{"date-parts":[[2023,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>The current study assessed the clinical characteristics of patients suffering from Behcet's disease (BD)\u2010associated oral ulcers and investigated the effect of these oral ulcers on the oral health\u2010related quality of life (OHRQoL).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This study included BD patients suffering from active oral ulcers, defined by the revised International Criteria for BD (ICBD) criteria. We collected BD and oral ulcers characteristics. The oral ulcer activity index and OHRQoL were measured by composite index (CI) and Oral Health Impact Profile\u201014 (OHIP\u201014), respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Genital and ocular manifestations were the most frequent. Ocular manifestations were the main diagnostic manifestation. The mean age of BD diagnosis and first oral ulcer appearance were 32.15\u00a0\u00b1\u00a08.96 and 29.62\u00a0\u00b1\u00a09.04, respectively. Minor oral ulcers were more frequent; solitary or multiple. CI revealed that pain was more severe than functional disability. OHIP\u201014 showed that patients suffered more often from pain and difficulties in eating. Patients reported feeling tense, being irritable, doing usual job with difficulty, and having less satisfying life.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>BD\u2010associated oral ulcers lead to poor quality of life. Female gender, multiple ulcers, and buccal mucosa were associated with more severe pain and functional disability as well as poorer quality of life.<\/jats:p><\/jats:sec>","DOI":"10.1111\/scd.12782","type":"journal-article","created":{"date-parts":[[2022,9,21]],"date-time":"2022-09-21T03:39:05Z","timestamp":1663731545000},"page":"435-442","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Effect of Behcet's disease\u2010associated oral ulcers on oral health related quality of life"],"prefix":"10.1111","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3794-2491","authenticated-orcid":false,"given":"Shereen","family":"Ali","sequence":"first","affiliation":[{"name":"Department of Oral Medicine and Periodontology, Faculty of Dentistry Cairo University  Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Clair Sobhy","family":"Nagieb","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine and Periodontology, Faculty of Dentistry Cairo University  Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hala Lotfy","family":"Fayed","sequence":"additional","affiliation":[{"name":"Department of Rheumatology &amp; Rehabilitation, Faculty of Medicine Cairo University  Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,9,20]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1054\/ijom.2002.0260"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/jop.12897"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10067\u2010005\u20100046\u20108"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601\u20100825.2005.01144.x"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/kew486"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10067\u2010019\u201004570\u2010w"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.12107"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u20100714.2009.00803.x"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.131249"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u20100714.2007.00514.x"},{"issue":"1","key":"e_1_2_8_12_1","first-page":"3","article-title":"Development and evaluation of the oral health impact profile","volume":"11","author":"Slade GD","year":"1994","journal-title":"Community Dent Health"},{"issue":"8","key":"e_1_2_8_13_1","first-page":"391","article-title":"Biostatistics 102: quantitative data \u2013 parametric & non\u2010parametric tests","volume":"44","author":"Chan YH","year":"2003","journal-title":"Singapore Med J"},{"issue":"10","key":"e_1_2_8_14_1","first-page":"498","article-title":"Biostatistics 103: qualitative data \u2013 tests of independence","volume":"44","author":"Chan YH","year":"2003","journal-title":"Singapore Med J"},{"issue":"12","key":"e_1_2_8_15_1","first-page":"614","article-title":"Biostatistics 104: correlational analysis","volume":"44","author":"Chan YH","year":"2003","journal-title":"Singapore Med J"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00296\u2010021\u201004990\u20105"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00296\u2010008\u20100741\u20102"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/1756\u2010185X.13598"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amsu.2020.03.010"},{"issue":"45","key":"e_1_2_8_20_1","first-page":"S58","article-title":"Beh\u00e7et's disease in Tunisia. 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