{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:21:58Z","timestamp":1787016118369,"version":"build-2736575974"},"reference-count":36,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2022,10,21]],"date-time":"2022-10-21T00:00:00Z","timestamp":1666310400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Special Care in Dentistry"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To evaluate the prevalence and significance of the malocclusion traits and orthodontic treatment needs of Down syndrome (DS) subjects with matched non\u2010syndromic (NS) controls.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methodology<\/jats:title>\n                    <jats:p>This cross\u2010sectional study involved 222 subjects (50% DS, 50% NS) who were matched by gender and age. The casts were digitized into three\u2010dimensional images. These images were used alongside the ten occlusal characteristics of the Dental Aesthetic Index (DAI) to determine malocclusion severity and the need for orthodontic treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      There were 58 (52.3%) females and 53 (47.7%) males with a mean age of 18.4\u00a0\u00b1\u00a08.4 years in both groups. The most common and significant (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a0.05) malocclusion traits among the DS subjects were missing teeth (56.2%), incisal spacing segments (73.0%), anterior maxillary irregularity (95.5%), mandibular overjet (36.0%), and full cusp deviation of the molar relationship (61.3%). On the other hand, increased maxillary overjet (69.3%) is a more significant (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a0.05) trait amongst NS subjects. There were 85 (76.6%) DS subjects who presented severe malocclusion, which implies a highly orthodontic treatment need (DAI\u00a0&gt;\u00a030). The DS showed some impact of malocclusion traits components of the DAI.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The occurrence of malocclusion was higher in DS, implying a higher need for orthodontic treatments than for NS subjects.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/scd.12790","type":"journal-article","created":{"date-parts":[[2022,10,21]],"date-time":"2022-10-21T08:19:45Z","timestamp":1666340385000},"page":"554-560","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Comparison of the malocclusion and orthodontic treatment needs of Down syndrome and non\u2010syndromic subjects by using the dental aesthetics index"],"prefix":"10.1111","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4750-9667","authenticated-orcid":false,"given":"Alizae Marny Fadzlin","family":"Syed Mohamed","sequence":"first","affiliation":[{"name":"Discipline of Orthodontics, Department of Family Oral Health, Faculty of Dentistry Universiti Kebangsaan Malaysia  Kuala Lumpur Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tan Zhen","family":"Wei","sequence":"additional","affiliation":[{"name":"Faculty of Dentistry Universiti Kebangsaan Malaysia  Kuala Lumpur Malaysia"},{"name":"T\u2010Care Dental Clinic  Skudai, Johor Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheh Jing","family":"Sean","sequence":"additional","affiliation":[{"name":"Faculty of Dentistry Universiti Kebangsaan Malaysia  Kuala Lumpur Malaysia"},{"name":"Oasis Dentalcare Dental Clinic  Ipoh, Perak Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tanti Irawati","family":"Rosli","sequence":"additional","affiliation":[{"name":"Discipline of Dental Public Health, Department of Family Oral Health, Faculty of 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