{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T02:01:08Z","timestamp":1747188068376,"version":"3.40.5"},"reference-count":10,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2022,12,8]],"date-time":"2022-12-08T00:00:00Z","timestamp":1670457600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Special Care in Dentistry"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Desomorphine is a composite of the self\u2010made illicit drug \u201ckrokodil\u201d, which is popular in Eastern Europe and other parts of the world. It causes toxic damage of different organs including bones. In this paper, a clinical portrait of the patient with drug\u2010induced osteonecrosis of mandible who refused surgical treatment in the early stages of the disease, is presented. At the time of first presentation, the patient displayed swelling of oral soft tissues and purulent discharge in the molar area of the right mandible. Radiographic examination demonstrated several small radiolucent lesions in the body of the mandible. The patient gave consent for surgical treatment and rehabilitation only after 12 months of the diagnosis. During this period of time, the necrosis of the mandibular bone progressed and a pathological fracture of the jaw was developed. Patient underwent surgical treatment \u2013 resection of the mandible. Management of drug\u2010induced jaw osteonecrosis is challenging as the necessity of dental and surgical treatment as well as treatment and rehabilitation of substance use disorder arises. Involvement of a multidisciplinary healthcare professionals team is essential in successful treatment of this pathology. The latter includes early surgical intervention\/medical treatment and rehabilitation from drug addiction.<\/jats:p>","DOI":"10.1111\/scd.12807","type":"journal-article","created":{"date-parts":[[2022,12,9]],"date-time":"2022-12-09T06:14:06Z","timestamp":1670566446000},"page":"685-688","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Progression of primarily untreated desomorphine drug induced jaw osteonecrosis: A case report"],"prefix":"10.1111","volume":"43","author":[{"given":"Nata","family":"Ramishvili","sequence":"first","affiliation":[{"name":"Institute of Medical and Public Health Research Ilia State University  Tbilisi Georgia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irakli","family":"Chachua","sequence":"additional","affiliation":[{"name":"School of Medicine New Vision University  Tbilisi Georgia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marika","family":"Zurmukhtashvili","sequence":"additional","affiliation":[{"name":"Faculty of Medicine European University  Tbilisi Georgia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ivane","family":"Abiatari","sequence":"additional","affiliation":[{"name":"Institute of Medical and Public Health Research Ilia State University  Tbilisi Georgia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5098-6726","authenticated-orcid":false,"given":"Luc","family":"Marks","sequence":"additional","affiliation":[{"name":"Special Care in Dentistry Department of Cranio \u2010 Maxillofacial Surgery University of Antwerp  Antwerp Belgium"},{"name":"Faculty of Medicine &amp; Health Science University of Antwerp  Belgium"},{"name":"Special Care in Dentistry Ghent University Hospital  Gent Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giorgi","family":"Dugashvili","sequence":"additional","affiliation":[{"name":"School of Medicine \u00a0Grigol Robakidze\u00a0University  Tbilisi Georgia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,12,8]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.forsciint.2015.02.001"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugpo.2013.05.009"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2014.03.008"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcms.2014.05.005"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2014.01.040"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2013.09.030"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugpo.2013.04.007"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2017.04.026"},{"key":"e_1_2_7_10_1","doi-asserted-by":"crossref","unstructured":"ChangC GreenspanA BeltranJ GershwinME.Chapter 13: Osteonecrosis. Kelley and Firestein's Textbook of Rheumatology.2017:1764\u20131787.e5. doi:10.1016\/B978\u20100\u2010323\u201031696\u20105.00103\u20100. Epub 2016 Aug 30. 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