{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T22:46:39Z","timestamp":1781822799279,"version":"3.54.5"},"reference-count":33,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2023,6,16]],"date-time":"2023-06-16T00:00:00Z","timestamp":1686873600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Special Care in Dentistry"],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and aim<\/jats:title><jats:p>Severe hemodynamic fluctuations during dental treatment can trigger highly undesirable physical reactions. A study was made to determine whether the administration of propofol and sevoflurane contributes to the stabilization of hemodynamic parameters during dental treatment in pediatric patients versus the use of local anesthesia alone.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and methods<\/jats:title><jats:p>Forty pediatric patients needing dental treatment were assigned to either general anesthesia with local anesthesia (study group [SG]) or local anesthesia alone (control group [CG]). Two percent sevoflurane in oxygen (100% oxygen, 5 L\/min) and continuous propofol infusion (target\u2010controlled infusion [TCI], 2 \u03bcg\/mL) were used as general anesthesia agents in SG; and 2% lidocaine with 1:80,000 adrenaline was used as local anesthesia in both groups. Heart rate, blood pressure and oxygen saturation were measured before starting dental treatment (baseline) and every 10 min during dental treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Blood pressure (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.001), heart rate (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.021) and oxygen saturation (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.007) decreased substantially after the administration of general anesthesia. The levels of these parameters subsequently remained low and then recovered at the end of the procedure. On the other hand, the oxygen saturation values remained closer to baseline in SG versus CG. In contrast, the hemodynamic parameters experienced lesser fluctuations in CG than in SG.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>General anesthesia affords more favorable cardiovascular parameters during the entire dental treatment in comparison to local anesthesia alone (blood pressure and heart rate decrease significantly and oxygen saturation proves more stable and with values closer to baseline), and allows dental treatment to be performed on healthy, lacking cooperative ability children who otherwise could not be treated with local anesthesia alone. No side effects were observed in either group.<\/jats:p><\/jats:sec>","DOI":"10.1111\/scd.12890","type":"journal-article","created":{"date-parts":[[2023,6,16]],"date-time":"2023-06-16T15:52:00Z","timestamp":1686930720000},"page":"563-574","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Comparison of hemodynamic changes with general or local anesthesia during dental treatment in pediatric patients: A prospective clinical study"],"prefix":"10.1111","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5104-6653","authenticated-orcid":false,"given":"Silvia","family":"P\u00e9rez\u2010Garc\u00eda","sequence":"first","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery International University of Catalonia Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johanna","family":"Acosta\u2010Ibarra","sequence":"additional","affiliation":[{"name":"Private practice in Barcelona Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5145-899X","authenticated-orcid":false,"given":"Juan\u2010Antonio","family":"Ruiz\u2010Roca","sequence":"additional","affiliation":[{"name":"Department of Stomatology, Faculty of Dentistry University of Murcia Murcia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Crist\u00f3bal","family":"A\u00f1ez","sequence":"additional","affiliation":[{"name":"Universitat Rovira i Virgili, Anesthetist Hospital Universitari de Tarragona Joan XXIII Tarragona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jordi","family":"Gargallo\u2010Albiol","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery International University of Catalonia Barcelona Spain"},{"name":"Department of Periodontics and Oral Medicine The University of Michigan, School of Dentistry Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,6,16]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.4317\/medoral.16.e541"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0722.1996.tb00074.x"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.1982.0114"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.17796\/jcpd.37.3.6u482603r0388558"},{"key":"e_1_2_9_6_1","first-page":"1303","article-title":"Intravenous sedation and hemodynamic changes during dental implant surgery","volume":"26","author":"Taguchi T","year":"2011","journal-title":"Int J Oral Maxillofac Implants"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1754-4505.2008.00055.x"},{"key":"e_1_2_9_8_1","first-page":"68","article-title":"Utility of bispectral index monitoring during deep sedation in pediatric dental patients","volume":"39","author":"Dag C","year":"2014","journal-title":"J Clin Pediatr Dent"},{"key":"e_1_2_9_9_1","first-page":"E496","article-title":"Criteria for selecting children with special needs for dental treatment under general anaesthesia","volume":"12","author":"Nova\u2010Garc\u00eda MJ","year":"2007","journal-title":"Med Oral Patol Oral Cir Bucal"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinane.2011.04.008"},{"key":"e_1_2_9_11_1","first-page":"110","article-title":"Guideline on the elective use of minimal, moderate, and deep sedation and general anesthesia for pediatric dental patients","volume":"27","author":"American Academy of Pediatric Dentistry","year":"2005","journal-title":"Pediatr Dent"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm10020182"},{"key":"e_1_2_9_13_1","unstructured":"Comittee on Economics. 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