{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T08:10:32Z","timestamp":1779264632856,"version":"3.51.4"},"reference-count":29,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2023,8,9]],"date-time":"2023-08-09T00:00:00Z","timestamp":1691539200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2023,8,9]],"date-time":"2023-08-09T00:00:00Z","timestamp":1691539200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Special Care in Dentistry"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Enamel renal syndrome is a rare genetic disorder transmitted through an autosomal recessive mode. It is featured by a hypoplastic amelogenesis imperfecta, delayed tooth eruption, gingival fibromatosis, and nephrocalcinosis. The aim of this study was to describe clinically, radiologically, and histologically the main features of enamel renal syndrome and to point out the role of dentists in early diagnosing this genetic disease.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and methods<\/jats:title>\n                    <jats:p>Our case of enamel renal syndrome was initially described by clinical, radiographic, and genealogic data, then complemented by ultrasound examination of the kidneys and microscopic observation of gingivae.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The study showed the presence of amelogenesis imperfecta (AI), several teeth impaction, gingival hyperplasia, bilateral nephrocalcinosis, and multiple calcifications in pulp, gingiva, dental follicle, and kidneys.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The patient was followed for a full mouth rehabilitation and also referred to a nephrology for global medical checkup. The dentist plays a key role in diagnosing genetic diseases and in referring patients for medical comprehensive care.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/scd.12915","type":"journal-article","created":{"date-parts":[[2023,8,9]],"date-time":"2023-08-09T22:06:10Z","timestamp":1691618770000},"page":"722-728","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Enamel renal syndrome: A case report with calcifications in pulp, gingivae, dental follicle and kidneys"],"prefix":"10.1111","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-7207-2939","authenticated-orcid":false,"given":"Rabeb","family":"Khalifa","sequence":"first","affiliation":[{"name":"Laboratory of Histology and Embryology Faculty of Dental Medicine of Monastir University of Monastir  Monastir Tunisia"},{"name":"ABCDF Laboratory for Biological Clinical and Dento\u2010Facial Approach University of Monastir, Avicenna Avenue  Monastir Tunisia"},{"name":"Department of Removable Prosthodontics Faculty of Dental Medicine University of Monastir  Monastir Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rym","family":"Kammoun","sequence":"additional","affiliation":[{"name":"Laboratory of Histology and Embryology Faculty of Dental Medicine of Monastir University of Monastir  Monastir Tunisia"},{"name":"ABCDF Laboratory for Biological Clinical and Dento\u2010Facial Approach University of Monastir, Avicenna Avenue  Monastir Tunisia"},{"name":"Department of Radiology University Dental Clinic  Monastir Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lamia","family":"Mansour","sequence":"additional","affiliation":[{"name":"ABCDF Laboratory for Biological Clinical and Dento\u2010Facial Approach University of Monastir, Avicenna Avenue  Monastir Tunisia"},{"name":"Department of Removable Prosthodontics Faculty of Dental Medicine University of Monastir  Monastir Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Touhami","family":"Ben Alaya","sequence":"additional","affiliation":[{"name":"Department of Radiology University Dental Clinic  Monastir Tunisia"},{"name":"Unity of Bioactive Natural Substances and Biotechnology Faculty of Dental Medicine University of Monastir  Monastir Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sonia","family":"Ghoul","sequence":"additional","affiliation":[{"name":"Laboratory of Histology and Embryology Faculty of Dental Medicine of Monastir University of Monastir  Monastir Tunisia"},{"name":"ABCDF Laboratory for Biological Clinical and Dento\u2010Facial Approach University of Monastir, Avicenna Avenue  Monastir Tunisia"},{"name":"International Faculty of Dental Medicine BioMed Unit College of Health Sciences International University of Rabat, Technopolis Parc, Rocade of Rabat\u2010Sal\u00e9, Sala\u2010Al Jadida  Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,8,9]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2020.605084"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1834\u20107819.1972.tb02747.x"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.4103\/jisp.jisp_532_18"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/1750\u20101172\u20109\u201084"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u20100714.1988.tb01332.x"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1159\/000322828"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00467\u2010008\u20101073\u2010x"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1003302"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmg.2020.104045"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471\u20102164\u20106\u201011"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/odi.12724"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.36187"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajhg.2011.04.005"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1159\/000349989"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471\u20102164\u20106\u201011"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034513512653"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2008.070520"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/jre.12666"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/odi.13369"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.14814\/phy2.15150"},{"issue":"3","key":"e_1_2_9_22_1","first-page":"67","article-title":"Factors influencing permanent teeth eruption. 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