{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T08:10:03Z","timestamp":1779264603978,"version":"3.51.4"},"reference-count":19,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2023,10,9]],"date-time":"2023-10-09T00:00:00Z","timestamp":1696809600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2023,10,9]],"date-time":"2023-10-09T00:00:00Z","timestamp":1696809600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Special Care in Dentistry"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Primary\u00a0oral mucosal melanoma (OMM) represents an extremely rare and aggressive tumor that arises from malignant transformation and clonal expansion of melanocytes in the oral cavity. The prognosis of patients affected by OMM is quite unfavorable, with survival rates lower than those described for patients with cutaneous melanoma.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case report<\/jats:title>\n                    <jats:p>Here, we report a case of OMM in a 59\u2010year\u2010old Caucasian woman, who was referred for evaluation of a large asymptomatic pigmented lesion on the left side of the hard palate under the removable total denture. Incisional biopsy was performed, and histopathological analysis revealed the proliferation of spindle\u2010shaped and pigmented epithelioid cells, with cellular pleomorphism. These cells were positive for Melan A, S\u2010100, HMB\u201045, SOX\u201010, and Ki\u201067 confirming the diagnosis of OMM. The patient underwent partial maxillectomy and adjuvant radiotherapy. After treatment, she was rehabilitated with a palatal obturator prosthesis and has been in follow\u2010up for 10 years with no evidence of disease. Due to the rarity in the oral cavity and the nonspecific signs and symptoms, the diagnosis of OMM is difficult and often overlooked.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      Therefore, multidisciplinary management from diagnosis, treatment, and rehabilitation is important to increase the expectation of cure\n                      <jats:styled-content>.<\/jats:styled-content>\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/scd.12928","type":"journal-article","created":{"date-parts":[[2023,10,10]],"date-time":"2023-10-10T00:26:54Z","timestamp":1696897614000},"page":"751-755","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["A primary oral mucosal melanoma of the hard palate with no recurrence: Report of a 10 years follow\u2010up"],"prefix":"10.1111","volume":"44","author":[{"given":"Ivan Jos\u00e9","family":"Correia\u2010Neto","sequence":"first","affiliation":[{"name":"Department of Oral Diagnosis, Piracicaba Dental School University of Campinas (UNICAMP)  Piracicaba S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcelo Brum","family":"Correa","sequence":"additional","affiliation":[{"name":"Head and neck surgeon, Private office, Piracicaba, S\u00e2o Paulo, Brazil  Piracicaba Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3725-8051","authenticated-orcid":false,"given":"Anna Lu\u00edza Damaceno","family":"Ara\u00fajo","sequence":"additional","affiliation":[{"name":"Head and Neck Surgery Department University of S\u00e3o Paulo Medical School (UFMUSP)  S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paulo Victor Mendes","family":"Penafort","sequence":"additional","affiliation":[{"name":"Department of Oral Diagnosis, Piracicaba Dental School University of Campinas (UNICAMP)  Piracicaba S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Carolina Evangelista","family":"Colafemina","sequence":"additional","affiliation":[{"name":"Department of Oral Diagnosis, Piracicaba Dental School University of Campinas (UNICAMP)  Piracicaba S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rog\u00e9rio de Andrade","family":"Elias","sequence":"additional","affiliation":[{"name":"Department of Oral Diagnosis, Piracicaba Dental School University of Campinas (UNICAMP)  Piracicaba S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2040-6617","authenticated-orcid":false,"given":"Alan Roger","family":"Santos\u2010Silva","sequence":"additional","affiliation":[{"name":"Department of Oral Diagnosis, Piracicaba Dental School University of Campinas (UNICAMP)  Piracicaba S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pablo Agustin","family":"Vargas","sequence":"additional","affiliation":[{"name":"Department of Oral Diagnosis, Piracicaba Dental School University of Campinas (UNICAMP)  Piracicaba S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M\u00e1rcio Ajudarte","family":"Lopes","sequence":"additional","affiliation":[{"name":"Department of Oral Diagnosis, Piracicaba Dental School University of Campinas (UNICAMP)  Piracicaba S\u00e3o Paulo 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