{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T01:59:04Z","timestamp":1747187944283,"version":"3.40.5"},"reference-count":24,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2024,5,2]],"date-time":"2024-05-02T00:00:00Z","timestamp":1714608000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Special Care in Dentistry"],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>The VACTERL association or Syndrome consists of Vertebral, Anorectal, Cardiac, Tracheo\u2013Esophageal, Renal, and Limb defects. The diagnosis relies on the presence of at least three of these structural abnormalities. This study reports a single case of a patient with VACTERL Syndrome (VS), aiming to assist dentists in recognizing the general aspects, systemic changes, and oral care related to this condition.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case report<\/jats:title><jats:p>A 14\u2010year\u2010old female patient medically diagnosed with VS. The study evaluated the presence of systemic alterations, medication use, behavioral deviations, cognitive development, and oral aspects. The patient exhibited cardiovascular alterations including a ventricular septal defect (C), anal atresia (A), polydactyly (considered limb alteration\u2014L), and scoliosis (a possible indication of vertebral anomalies\u2014V). In the intraoral examination, findings included tooth crowding, enamel hypomineralization in several teeth, a deep and atretic palate, generalized gingivitis, bleeding, gingival hyperplasia, Class III malocclusion, and a right unilateral crossbite.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Patients diagnosed with VACTERL syndrome experience significant systemic impairments. The research subject presented compromised oral health, challenges in dental management, delays in neuropsychomotor development, though these are not inherent to the syndrome. It is crucial to prevent oral diseases and provide early dental care for these patients to avoid the need for complex and invasive dental treatments due to systemic impairments.<\/jats:p><\/jats:sec>","DOI":"10.1111\/scd.13006","type":"journal-article","created":{"date-parts":[[2024,5,2]],"date-time":"2024-05-02T07:09:31Z","timestamp":1714633771000},"page":"1377-1382","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Vacterl syndrome: Medical and stomatological considerations for comprehensive patient management"],"prefix":"10.1111","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6153-6031","authenticated-orcid":false,"given":"Cristhiane Ol\u00edvia Ferreira","family":"Do Amaral","sequence":"first","affiliation":[{"name":"Faculty of Dentistry University of\u00a0Oeste\u00a0Paulista \u2010 Unoeste  S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Fl\u00e1via Ferreira Barros De","family":"Souza","sequence":"additional","affiliation":[{"name":"Dentistry \u2010 University of Western Sao Paulo \u2010 Unoeste  S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guilherme Peratelli","family":"Carlucci","sequence":"additional","affiliation":[{"name":"Dentistry \u2010 University of Western Sao Paulo \u2010 Unoeste  S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leticia Da Silva","family":"Lima","sequence":"additional","affiliation":[{"name":"Dentistry \u2010 University of Western Sao Paulo \u2010 Unoeste  S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariana Ol\u00edvia Ferreira Do","family":"Amaral","sequence":"additional","affiliation":[{"name":"Medical School University of West S\u00e3o Paulo  S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabiana Gouveia","family":"Straioto","sequence":"additional","affiliation":[{"name":"Department of Prosthodontics and\u00a0Geriatic\u00a0Dentistry, Dental School University of Western Sao Paulo  S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,5,2]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.4081\/cp.2013.e5"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/1750\u20101172\u20106\u201056"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00383-007-1891-0"},{"key":"e_1_2_5_5_1","first-page":"39","article-title":"Esophageal atresia in newborns: a wide spectrum from isolated forms to a full VACTERL phenotype?","author":"La Placa SL","year":"2013","journal-title":"Ital J Pediatr"},{"issue":"2","key":"e_1_2_5_6_1","first-page":"203","article-title":"Ventricular septal defect closure in a patient with VACTERL syndrome","volume":"35","author":"Hatemi AC","year":"2008","journal-title":"Tex Heart Inst J"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00383-012-3073-y"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/ejhg.2013.58"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1590\/S1516-31802010000200011"},{"key":"e_1_2_5_10_1","first-page":"2009","article-title":"VACTERL Association: a dental case study","volume":"14","author":"Wilbur JL","year":"2010","journal-title":"Columbia Dent Rev"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.4103\/0972-3919.125776"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11420-006-9021-4"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0035-1566297"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00439-010-0814-7"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1136\/jmedgenet-2015-103554"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.4103\/2249-4847.123104"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.11606\/issn.2176-7262.v50i3p201-205"},{"issue":"2","key":"e_1_2_5_18_1","first-page":"132","article-title":"Presentation of a case with multiple congenital malformations: asociaci\u00f3n VACTERL","volume":"14","author":"Rueda SCM","year":"2011","journal-title":"Med Unab"},{"issue":"1","key":"e_1_2_5_19_1","first-page":"109","article-title":"Treatment of cardiac patients in the dental clinic","volume":"4","author":"Barros MNF","year":"2011","journal-title":"Rev Health Res"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0000000000001169"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/apa.13973"},{"issue":"1","key":"e_1_2_5_22_1","first-page":"7","article-title":"Vacterl syndrome: different dental findings","volume":"4","author":"Yi\u011fit T","year":"2021","journal-title":"Turk J Med Sci Life"},{"key":"e_1_2_5_23_1","unstructured":"Brasil. 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