{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T17:59:35Z","timestamp":1773338375066,"version":"3.50.1"},"reference-count":28,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2024,4,29]],"date-time":"2024-04-29T00:00:00Z","timestamp":1714348800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Special Care in Dentistry"],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Nevoid basal cell carcinoma syndrome (NBCCS) is an autosomal dominant multisystemic disorder characterized by the presence of multiple odontogenic keratocysts (OKC), which are a hallmark feature of the syndrome. The treatment of these OKC poses challenges due to their high recurrence rates and the myriad of management options available.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case Report<\/jats:title><jats:p>We describe here a case of NBCCS diagnosed in an 11\u2010year\u2010old girl who presented with multiple OKC in the jaws. Chest and cranial radiographs showed no abnormalities in the ribs and the cerebral falx, respectively. Cephalometric analysis indicated mandibular retrusion, a skeletal class II relationship, and a convex profile. The treatment approach involved a personalized strategy tailored for each cyst, comprising marsupialization followed by enucleation. This approach aimed to minimize surgical trauma and to reduce the risk of recurrence. The patient underwent regular follow\u2010up appointments, demonstrating successful outcomes with no signs of recurrence or <jats:italic>de novo<\/jats:italic> OKC observed over a 32\u2010month period.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Clinicians should consider lesion characteristics and patient cooperation when determining treatment strategies for the optimization of outcomes for children and adolescents with NBCCS and multiple OKC.<\/jats:p><\/jats:sec>","DOI":"10.1111\/scd.13007","type":"journal-article","created":{"date-parts":[[2024,4,30]],"date-time":"2024-04-30T04:19:28Z","timestamp":1714450768000},"page":"1383-1392","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Conservative management of multiple odontogenic keratocysts in a child with nevoid basal cell carcinoma syndrome: A case report"],"prefix":"10.1111","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6599-3950","authenticated-orcid":false,"given":"Jos\u00e9 Alcides Almeida","family":"de Arruda","sequence":"first","affiliation":[{"name":"Department of Oral Diagnosis and Pathology School of Dentistry Universidade Federal do Rio de Janeiro  Rio de Janeiro Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kawhan Felipe Alves","family":"de Lima","sequence":"additional","affiliation":[{"name":"Dental Department Hospital Nossa Senhora Aparecida Iturama Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Osias Vieira","family":"de Oliveira Filho","sequence":"additional","affiliation":[{"name":"Division of Oral Pathology School of Pharmacy, Dentistry and Nursing Universidade Federal do Cear\u00e1  Fortaleza Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luciana Estevam","family":"Simonato","sequence":"additional","affiliation":[{"name":"School of Dentistry Universidade Brasil  Fernand\u00f3polis Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3259-606X","authenticated-orcid":false,"given":"Bruno Augusto Benevenuto","family":"de Andrade","sequence":"additional","affiliation":[{"name":"Department of Oral Diagnosis and Pathology School of Dentistry Universidade Federal do Rio de Janeiro  Rio de Janeiro Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2295-7968","authenticated-orcid":false,"given":"Saygo","family":"Tomo","sequence":"additional","affiliation":[{"name":"Department of Pathology School of Dentistry Universidade de S\u00e3o Paulo  S\u00e3o Paulo 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