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He was initially treated conservatively, using antimicrobial photodynamic therapy (aPDT), antibiotic therapy, and the PENTO protocol. However, the patient evolved with a pathological fracture in the mandibular parasymphysis, requiring surgical reconstruction.<\/jats:p><\/jats:sec><jats:sec><jats:title>Final considerations<\/jats:title><jats:p>Pathological fracture of the mandible is a complication of MRONJ that compromises the patient's quality of life. The management of patients with MRONJ is complex and challenging.<\/jats:p><\/jats:sec>","DOI":"10.1111\/scd.13035","type":"journal-article","created":{"date-parts":[[2024,7,4]],"date-time":"2024-07-04T04:54:03Z","timestamp":1720068843000},"page":"1558-1563","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Mandibular fracture in medication\u2010associated osteonecrosis following infliximab therapy: A case report"],"prefix":"10.1111","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6301-8767","authenticated-orcid":false,"given":"Waleska Tychanowicz","family":"Kolodziejwski","sequence":"first","affiliation":[{"name":"Multiprofessional Residency Program in Oncology and Hematology Complexo Hospital de Cl\u00ednicas Universidade Federal do Paran\u00e1  Curitiba Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Camila Adriane 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