{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T12:04:30Z","timestamp":1787313870980,"version":"build-2736575974"},"reference-count":38,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2024,9,11]],"date-time":"2024-09-11T00:00:00Z","timestamp":1726012800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Special Care in Dentistry"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To assess the impact of treatment with orthodontic aligners (OA) on oral health\u2010related quality of life (OHRQoL) in patients with trisomy 21 (T21) compared to non\u2010syndromic patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and methods<\/jats:title>\n                    <jats:p>\n                      The sample consisted of 30 patients, both sexes, aged between 11 and 35 years, divided into two groups: T21 (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a010, patients with T21, treated prospectively) and CONTROL (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a020, control group, non\u2010syndromic patients, from the Orthodontic Laboratory of UNOPAR). In both groups, patients were treated with Invisalign orthodontic aligners (Align Technology), following the same treatment parameters. Participants, assisted by their caregivers, when necessary, answered Oral Health Impact Profile (OHIP\u201014) instrument and the patient's guardians answered the Oral Health Scale for People with Down's syndrome (OHDS) instrument, before (T0) and after 30 (T1), 180 (T2), and 365 (T3) days from the start of treatment. Friedman tests with Bonferroni correction and Mann\u2013Whitney tests were used (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a0.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      For the OHDS instrument, it was observed that for the eating and communication domains and an overall score, the treatment with OA positively impacted the lives of T21 patients (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a0.05). Regarding the OHIP\u201014 instrument, the intragroup evaluation showed that in the CONTROL group, there was no significant difference between the evaluated times; while for the T21 group, there was a significant positive impact (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a0.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The results showed that the treatment with aligners positively impacted the OHRQoL of T21 patients, and these results were perceived by caregivers, mainly in relation to issues related to eating and communication.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/scd.13055","type":"journal-article","created":{"date-parts":[[2024,9,12]],"date-time":"2024-09-12T00:15:52Z","timestamp":1726100152000},"page":"1781-1787","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Impact of orthodontic treatment with aligners on the oral health\u2010related quality of life of patients with trisomy 21"],"prefix":"10.1111","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-9114-7715","authenticated-orcid":false,"given":"Andr\u00e9","family":"Taniguchi","sequence":"first","affiliation":[{"name":"Department of Orthodontics Universidade Anhanguera\/Uniderp  Campo Grande Mato Grosso do Sul Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4350-0828","authenticated-orcid":false,"given":"J\u00e9ssica Madeira","family":"Bittencourt","sequence":"additional","affiliation":[{"name":"Department of Pediatric Dentistry Universidade Federal de Minas Gerais  Belo Horizonte Minas Gerais Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3968-1638","authenticated-orcid":false,"given":"Saul Martins","family":"Paiva","sequence":"additional","affiliation":[{"name":"Department of Pediatric Dentistry Universidade Federal de Minas Gerais  Belo Horizonte Minas Gerais Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4368-8568","authenticated-orcid":false,"given":"Thais Maria Freire","family":"Fernandes","sequence":"additional","affiliation":[{"name":"Department of Orthodontics Universidade Anhanguera\/Uniderp  Campo Grande Mato Grosso do Sul Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2684-0943","authenticated-orcid":false,"given":"Marcio Rodriguez de","family":"Almeida","sequence":"additional","affiliation":[{"name":"Department of Orthodontics Universidade Anhanguera\/Uniderp  Campo Grande Mato Grosso do Sul Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4283-1051","authenticated-orcid":false,"given":"Renata Rodrigues de","family":"Almeida\u2010Pedrin","sequence":"additional","affiliation":[{"name":"Department of Orthodontics Universidade Anhanguera\/Uniderp  Campo Grande Mato Grosso do Sul Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9658-1652","authenticated-orcid":false,"given":"Ana Cl\u00e1udia de Castro Ferreira","family":"Conti","sequence":"additional","affiliation":[{"name":"Department of Orthodontics Universidade Anhanguera\/Uniderp  Campo Grande Mato Grosso do Sul Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4342-8907","authenticated-orcid":false,"given":"Roberto","family":"Bespalez\u2010Neto","sequence":"additional","affiliation":[{"name":"Department of Orthodontics Universidade Anhanguera\/Uniderp  Campo Grande Mato Grosso do Sul Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2285-5179","authenticated-orcid":false,"given":"Paula Vanessa","family":"Pedron Oltramari","sequence":"additional","affiliation":[{"name":"Department of Orthodontics Universidade Anhanguera\/Uniderp  Campo Grande Mato Grosso do Sul Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,9,11]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034511399918"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2022.957876"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/872367"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/scd.12444"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.9771\/cmbio.v9i1.4732"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/ipd.12491"},{"key":"e_1_2_6_8_1","first-page":"42","article-title":"Estudo sobre o tratamento funcional ortop\u00e9dico e ortod\u00f4ntico em paciente portador da S\u00edndrome de Down com aparelhos pr\u00e9\u2010fabricados","author":"Scariot D","year":"2011","journal-title":"Odonto Mag"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.2319\/062813-480.1"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.61872\/sdj-2021-03-727"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1597\/10-192"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajodo.2016.04.019"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/j.0022-0337.2009.73.5.tb04730.x"},{"key":"e_1_2_6_14_1","first-page":"85","article-title":"Orthodontic considerations in individuals with Down syndrome: a case report","volume":"69","author":"Desai SS","year":"1999","journal-title":"Angle Orthod"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.12968\/denu.2012.39.4.254"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/ortho\/30.4.348"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00056-007-0655-8"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00056-005-0436-1"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00056-005-0429-0"},{"key":"e_1_2_6_20_1","first-page":"158","article-title":"Impact of self\u2010esteem on the relationship between orthodontic treatment and the oral health\u2010related quality of life in patients after orthodontic treatment \u2013 a systematic review","volume":"94","author":"Mandava P","year":"2021","journal-title":"Med Pharm Rep"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.2209\/tdcpublication.55.199"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6831-14-67"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.2319\/122014.1"},{"key":"e_1_2_6_24_1","article-title":"Impact of orthodontic treatment with aligners and fixed appliances on OHRQoL: a randomized clinical trial","author":"Borsato TTBJ","year":"2021","journal-title":"Braz Oral Res"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/ocr.12431"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.2319\/110620-917.1"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/joor.13130"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.4041\/kjod.2021.51.5.329"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1590\/S2176-94512010000600008"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0528.1997.tb00941.x"},{"key":"e_1_2_6_31_1","first-page":"224","article-title":"Validity of an instrument assessing oral health problems in people with Down syndrome","volume":"22","author":"Allison PJ","year":"2005","journal-title":"Community Dent Health"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7525-11-4"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/scd.12321"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.2319\/010509-9.1"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajodo.2018.01.013"},{"key":"e_1_2_6_36_1","first-page":"29","article-title":"Ortopedia e Ortodontia em crian\u00e7as com S\u00edndrome de Down","volume":"1","author":"Carvalho TM","year":"2017","journal-title":"Revista ci\u00eancias e odontologia"},{"key":"e_1_2_6_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jormas.2021.01.007"},{"key":"e_1_2_6_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1079-2104(97)90343-7"},{"key":"e_1_2_6_39_1","article-title":"Patients with Autism Spectrum Disorders: strategy for orthodontic care","volume":"12","author":"Acharya SS","year":"2018","journal-title":"J Clin Diagn Res"}],"container-title":["Special Care in Dentistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/scd.13055","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,13]],"date-time":"2024-11-13T08:45:46Z","timestamp":1731487546000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/scd.13055"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,11]]},"references-count":38,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024,11]]}},"alternative-id":["10.1111\/scd.13055"],"URL":"https:\/\/doi.org\/10.1111\/scd.13055","archive":["Portico"],"relation":{},"ISSN":["0275-1879","1754-4505"],"issn-type":[{"value":"0275-1879","type":"print"},{"value":"1754-4505","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,9,11]]},"assertion":[{"value":"2024-04-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-08-08","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-09-11","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}