{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T09:19:57Z","timestamp":1773047997015,"version":"3.50.1"},"reference-count":22,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,1,16]],"date-time":"2025-01-16T00:00:00Z","timestamp":1736985600000},"content-version":"vor","delay-in-days":15,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Special Care in Dentistry"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Renal tubular acidosis (RTA) is a group of disorders in which there is an alteration in acid\u2013base homeostasis because of the impairment of nephrons to excrete hydrogen ions or reabsorb bicarbonate ions, resulting in chronic metabolic acidosis. RTA is an important cause of rickets, particularly \u2018resistant rickets\u2019. Dental manifestations frequently reported in patients with RTA include enamel hypoplasia and amelogenesis imperfecta, affecting permanent dentition. To the best of our knowledge, the literature pertaining to the dental manifestations in RTA with secondary rickets is scarce. This case highlights oral manifestations in a 6\u2010year\u2010old girl with RTA, distal, four with haemolytic anaemia a rare form diagnosed on genetic testing, and refractory rickets having multiple missing teeth and enamel hypo\u2010mineralisation. The radiograph revealed alveolar bone loss in both jaws with widened pulp chambers and root canals in primary teeth. Pre\u2010eruptive enamel breakdown in multiple unerupted permanent teeth was also evident radiographically.<\/jats:p>","DOI":"10.1111\/scd.13101","type":"journal-article","created":{"date-parts":[[2025,1,16]],"date-time":"2025-01-16T07:25:32Z","timestamp":1737012332000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Oral Manifestations in a Child With Distal Renal Tubular Acidosis, and Refractory Rickets"],"prefix":"10.1111","volume":"45","author":[{"given":"Nikhil","family":"Shrivastava","sequence":"first","affiliation":[{"name":"Department of Pediatric and Preventive Dentistry Centre for Dental Education and Research AIIMS  New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saurabh","family":"Sharma","sequence":"additional","affiliation":[{"name":"Department of Pediatric and Preventive Dentistry Centre for Dental Education and Research AIIMS  New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2924-8857","authenticated-orcid":false,"given":"Morankar","family":"Rahul","sequence":"additional","affiliation":[{"name":"Department of Pediatric and Preventive Dentistry Centre for Dental Education and Research AIIMS  New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6747-5110","authenticated-orcid":false,"given":"Nitesh","family":"Tewari","sequence":"additional","affiliation":[{"name":"Department of Pediatric and Preventive Dentistry Centre for Dental Education and Research AIIMS  New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kalpana","family":"Bansal","sequence":"additional","affiliation":[{"name":"Department of Pediatric and Preventive Dentistry Centre for Dental Education and Research AIIMS  New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vijay","family":"Mathur","sequence":"additional","affiliation":[{"name":"Department of Pediatric and Preventive Dentistry Centre for Dental Education and Research AIIMS  New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,1,16]]},"reference":[{"key":"e_1_2_9_2_1","first-page":"1","article-title":"Distal Renal Tubular Acidosis: A Systematic Approach From Diagnosis to Treatment","volume":"1","author":"Giglio S.","year":"2021","journal-title":"Journal of Nephrology"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02734150"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-018-3965-8"},{"key":"e_1_2_9_5_1","first-page":"321","article-title":"Long\u2010Term Outcome in Children With Primary Distal Renal Tubular Acidosis","volume":"42","author":"Bajpai A.","year":"2005","journal-title":"Indian Pediatrics"},{"issue":"1","key":"e_1_2_9_6_1","first-page":"17","article-title":"Rickets in Renal Tubular Acidosis: A Clinical Appraisal","volume":"1","author":"Agrawal C.","year":"2020","journal-title":"Journal of Clinical and Experimental Nephrology"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12098-012-0900-z"},{"key":"e_1_2_9_8_1","first-page":"1153","article-title":"The Development of the Human Dentition","volume":"28","author":"Massler M.","year":"1941","journal-title":"Journal of the American Dental Association"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-015-3083-9"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.6065\/apem.2013.18.3.152"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12325-020-01587-5"},{"issue":"3","key":"e_1_2_9_12_1","first-page":"78","article-title":"Dental Findings in Patients With Renal Tubular Acidosis","volume":"4","author":"Ferreira S. B.","year":"2016","journal-title":"Journal of Clinical Pediatric Dentistry"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1590\/2175-8239-jbn-2018-0105"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0722.1984.tb01287.x"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/374945"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/bdrc.20136"},{"key":"e_1_2_9_17_1","first-page":"2013","article-title":"The Dental Management of Troublesome Twos: Renal Tubular Acidosis and Rampant Caries","volume":"2013","author":"Sandhyarani B.","year":"2013","journal-title":"BMJ Case Report"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pdj.2023.06.002"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.adaj.2021.12.009"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1590\/S1807-59322010001000017"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41405-023-00129-9"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2012.01.010"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdsr.2022.06.002"}],"container-title":["Special Care in Dentistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/scd.13101","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/scd.13101","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/scd.13101","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T08:23:37Z","timestamp":1773044617000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/scd.13101"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":22,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["10.1111\/scd.13101"],"URL":"https:\/\/doi.org\/10.1111\/scd.13101","archive":["Portico"],"relation":{},"ISSN":["0275-1879","1754-4505"],"issn-type":[{"value":"0275-1879","type":"print"},{"value":"1754-4505","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"2024-05-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-12-01","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-01-16","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e13101"}}