{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T00:33:57Z","timestamp":1790296437197,"version":"4.1.0"},"reference-count":48,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,3,15]],"date-time":"2025-03-15T00:00:00Z","timestamp":1741996800000},"content-version":"vor","delay-in-days":14,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Special Care in Dentistry"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>Chronic kidney disease (CKD), a widespread health problem marked by a gradual loss of kidney function, presents unique challenges in various aspects of patient care. As such, this case series aimed to assess the feasibility of dental implants in end\u2010stage renal disease (ESRD) patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Parathyroid hormone (PTH) levels were measured at the time of implant placement and implant uncovering. Radiographic evaluations were performed at 7, 15, 30, 90, and 180 days after implant placement and 180 days after prosthetic rehabilitation. Bone remodeling was evaluated based on the values of radiographic marginal bone loss, measured as the distance between the implant shoulder and the marginal bone levels.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Fifteen patients with ESRD received a total of 27 implants (5 in the maxilla and 22 in the mandible) installed in different regions, with a diameter of 3.75\u00a0mm, height of 8.5\u00a0mm, platform of 4.1\u00a0mm, and Morse taper connection. No correlation was found between PTH levels and primary implant stability (<jats:italic>\u03c1<\/jats:italic>\u00a0=\u00a00.04, <jats:italic>p<\/jats:italic> value\u00a0=\u00a00.860). PTH levels ranged from 105.1 to 1965\u00a0pg\/mL (mean 613.51\u00a0\u00b1\u00a0494.38\u00a0pg\/mL). Only one implant did not demonstrate primary stability during surgery, the others ranged from 15\u00a0 to 50\u00a0Ncm of stability. Seven implants failed during the evaluation due to varying degrees of bone loss. There was no significant effect of primary stability or PTH levels on implant loss.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Accelerated marginal bone loss within 6 months and reduced osseointegration in ESRD patients may lead to early implant loss and treatment challenges.<\/jats:p><\/jats:sec>","DOI":"10.1111\/scd.70014","type":"journal-article","created":{"date-parts":[[2025,3,15]],"date-time":"2025-03-15T07:49:57Z","timestamp":1742024997000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Dental Implants in Patients With End\u2010Stage Renal Disease: A Case Series"],"prefix":"10.1111","volume":"45","author":[{"given":"Gustavo Vargas da Silva","family":"Salom\u00e3o","sequence":"first","affiliation":[{"name":"Department of Stomatology School of Dentistry, University of S\u00e3o Paulo  S\u00e3o Paulo Brazil"},{"name":"Division of Implantology School of Dentistry, S\u00e3o Leopoldo Mandic  S\u00e3o Paulo Brazil"},{"name":"Division of Implantology School of Dentistry, Ibirapuera University  S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel I.","family":"Sendyk","sequence":"additional","affiliation":[{"name":"Department of Stomatology School of Dentistry, University of S\u00e3o Paulo  S\u00e3o Paulo Brazil"},{"name":"Division of Implantology School of Dentistry, S\u00e3o Leopoldo Mandic  S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9573-2858","authenticated-orcid":false,"given":"Karem L.","family":"Ortega","sequence":"additional","affiliation":[{"name":"Department of Stomatology School of Dentistry, University of S\u00e3o Paulo  S\u00e3o Paulo Brazil"},{"name":"Oral Medicine, Oral Surgery and Implantology Unit (MedOralRes), Faculty of Medicine and Dentistry University of Santiago de Compostela  Santiago de Compostela Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4856-5417","authenticated-orcid":false,"given":"Andr\u00e9 Luiz Ferreira","family":"Costa","sequence":"additional","affiliation":[{"name":"Post\u2010Graduate Program in Dentistry at the Cruzeiro do Sul University  S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruna","family":"Di Profio","sequence":"additional","affiliation":[{"name":"Department of Stomatology School of Dentistry, University of S\u00e3o Paulo  S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1842-9521","authenticated-orcid":false,"given":"Paulo Henrique","family":"Braz\u2010Silva","sequence":"additional","affiliation":[{"name":"Department of Stomatology School of Dentistry, University of S\u00e3o Paulo  S\u00e3o Paulo Brazil"},{"name":"Laboratory of Virology, Institute of Tropical Medicine, School of Medicine, University of S\u00e3o Paulo  S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudio M.","family":"Pannuti","sequence":"additional","affiliation":[{"name":"Department of Stomatology School of Dentistry, University of S\u00e3o Paulo  S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,3,15]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(13)60687\u2010XTitle"},{"issue":"1","key":"e_1_2_8_3_1","first-page":"7","article-title":"Taxa de Filtra\u00e7\u00e3o Glomerular Estimada em Adultos: Caracter\u00edsticas e Limita\u00e7\u00f5es das Equa\u00e7\u00f5es Utilizadas","volume":"48","author":"Souza Brito T. 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