{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T09:18:20Z","timestamp":1773047900660,"version":"3.50.1"},"reference-count":76,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,5,26]],"date-time":"2025-05-26T00:00:00Z","timestamp":1748217600000},"content-version":"vor","delay-in-days":25,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Special Care in Dentistry"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>This systematic review aims to investigate craniofacial symptoms, oral healthcare requirements, and management approaches for children diagnosed with Fetal Alcohol Spectrum Disorder (FASD).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Electronic searches were conducted across five databases (PubMed, Embase, Cochrane Library, Scopus, Web of Science, and LILACS). The inclusion criteria focused on original research for children with FASD, up to 18 years, emphasizing craniofacial symptoms, oral health, and management protocols. Data extraction was performed independently by two researchers using predetermined criteria. The JBI Critical Appraisal Tool was used to assess the risk of bias in the selected studies. PICO criteria guided study selection, with a focus on low risk of bias. Data analysis was carried out independently by two researchers.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among 361 identified papers, 215 were screened, and 16 studies meeting research criteria were included. The findings established a body of evidence linking characteristic craniofacial symptoms to FASD. They highlighted heightened oral health needs for children with FASD, emphasizing the significance of frequent recall and preventive measures.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This review solidifies the connection between maternal alcohol consumption during pregnancy and dentofacial complications in children with FASD, including cleft lip\/palate, malocclusion, increased DMFT, and craniofacial dysmorphia. It underscores the pivotal role of pediatric dentists in early identification and intervention.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/scd.70060","type":"journal-article","created":{"date-parts":[[2025,5,27]],"date-time":"2025-05-27T00:35:36Z","timestamp":1748306136000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Craniofacial Manifestation and Oral Health Care Needs in Pediatric Population With Fetal Alcohol Syndrome: A Systematic Review"],"prefix":"10.1111","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1156-3357","authenticated-orcid":false,"given":"Shannon","family":"Samuel","sequence":"first","affiliation":[{"name":"Department of Pedodontics and Preventive Dentistry Christian Dental College  Ludhiana India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8143-4051","authenticated-orcid":false,"given":"Joe Mathew","family":"Cherian","sequence":"additional","affiliation":[{"name":"Department of Pedodontics and Preventive Dentistry Christian Dental College  Ludhiana India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0490-0570","authenticated-orcid":false,"given":"Mebin George","family":"Mathew","sequence":"additional","affiliation":[{"name":"Department of Pedodontics and Preventive Dentistry Christian Dental College  Ludhiana India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7739-9994","authenticated-orcid":false,"given":"Alpana","family":"Kumari","sequence":"additional","affiliation":[{"name":"Department of Pedodontics and Preventive Dentistry Christian Dental College  Ludhiana India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abi M.","family":"Thomas","sequence":"additional","affiliation":[{"name":"Department of Pedodontics and Preventive Dentistry Christian Dental College  Ludhiana India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6384-3468","authenticated-orcid":false,"given":"Nirmal","family":"Kurian","sequence":"additional","affiliation":[{"name":"Department of Prosthodontics and Crown and Bridge Christian Dental College Ludhiana  Ludhiana India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,5,26]]},"reference":[{"key":"e_1_2_10_2_1","unstructured":"Centers for Disease Control and Prevention \u201cBasics about FASDs \u201dCenters for Disease Control and Prevention accessed March 10 2025 https:\/\/www.cdc.gov\/ncbddd\/fasd\/facts.html."},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapediatrics.2017.1919"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/acer.14317"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(15)01345-8"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(99)70453-1"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1530-0277.1997.tb03754.x"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-199004000-00003"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11065-011-9167-9"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/scd.12993"},{"key":"e_1_2_10_11_1","volume-title":"Cochrane Handbook for Systematic Reviews of Interventions","author":"Higgins J. 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