{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,2]],"date-time":"2026-01-02T13:14:47Z","timestamp":1767359687621,"version":"3.48.0"},"reference-count":30,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,11,24]],"date-time":"2025-11-24T00:00:00Z","timestamp":1763942400000},"content-version":"vor","delay-in-days":23,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Special Care in Dentistry"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This systematic review aimed to assess the available literature on the subgingival bacterial microbiota profiles of PLHIV undergoing HAART.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>This research was conducted in accordance with the PRISMA guidelines. Electronic searches were performed in the Cochrane Library, LILACS, PubMed, and Science Direct databases to identify primary studies evaluating the subgingival bacterial microbiota of individuals living with HIV\u20101 undergoing HAART. The search was performed by two independent researchers and covered the period from January 2001 to July 2022. Studies published in English, Portuguese, and Spanish were included.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 457 articles were initially retrieved. Of these, 9 met the eligibility criteria. The included studies revealed a high frequency of periodontal pathogens among individuals living with HIV\u20101 on HAART, including\n                      <jats:italic>Treponema denticola<\/jats:italic>\n                      (44%,\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a04 studies)\n                      <jats:italic>and Porphyromonas gingivalis<\/jats:italic>\n                      (33%,\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a03 studies), as well as species not commonly found in patients with periodontal disease, such as\n                      <jats:italic>Enterococcus faecalis<\/jats:italic>\n                      (33%,\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a02 studies).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      According to the present findings, the most frequently identified subgingival bacterial species in patients living with HIV\u20101 and receiving antiretroviral therapy were\n                      <jats:italic>T. denticola<\/jats:italic>\n                      and\n                      <jats:italic>P. gingivalis<\/jats:italic>\n                      , without establishing a consistent or unique microbiological profile.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/scd.70121","type":"journal-article","created":{"date-parts":[[2025,11,25]],"date-time":"2025-11-25T07:40:15Z","timestamp":1764056415000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Subgingival Bacterial Microbiota Profile of People Living With HIV\u20101 Under HAART: A Systematic Review"],"prefix":"10.1111","volume":"45","author":[{"given":"Tatiana Pinheiro","family":"de Macedo","sequence":"first","affiliation":[{"name":"Postgraduate Program in Dentistry, Faculty of Dentistry, Est\u00e1cio de S\u00e1 University\u2010IDOMED  Rio de Janeiro Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7889-6765","authenticated-orcid":false,"given":"Cristiane","family":"Gon\u00e7alves","sequence":"additional","affiliation":[{"name":"Postgraduate Program in Dentistry, Faculty of Dentistry, Est\u00e1cio de S\u00e1 University\u2010IDOMED  Rio de Janeiro Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4388-6310","authenticated-orcid":false,"given":"Lucio Souza","family":"Gon\u00e7alves","sequence":"additional","affiliation":[{"name":"Postgraduate Program in Dentistry, Faculty of Dentistry, Est\u00e1cio de S\u00e1 University\u2010IDOMED  Rio de Janeiro Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9278-5068","authenticated-orcid":false,"given":"Priscila Pereira Pavan","family":"Vidal","sequence":"additional","affiliation":[{"name":"Postgraduate Program in Dentistry, Faculty of Dentistry, Est\u00e1cio de S\u00e1 University\u2010IDOMED  Rio de Janeiro Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5848-404X","authenticated-orcid":false,"given":"Josu\u00e9 da Costa","family":"Lima\u2010Junior","sequence":"additional","affiliation":[{"name":"Postgraduate Program in Dentistry, Faculty of Dentistry, Est\u00e1cio de S\u00e1 University\u2010IDOMED  Rio de Janeiro Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6299-4432","authenticated-orcid":false,"given":"Mario Vianna","family":"Vettore","sequence":"additional","affiliation":[{"name":"Department of Dentistry and Oral Health Aarhus University  Aarhus Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1887-289X","authenticated-orcid":false,"given":"Rodrigo Carvalho de","family":"Souza","sequence":"additional","affiliation":[{"name":"Postgraduate Program in Dentistry, Faculty of Dentistry, Est\u00e1cio de S\u00e1 University\u2010IDOMED  Rio de Janeiro Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,11,24]]},"reference":[{"volume-title":"The Urgency of Now: AIDS at a Crossroads","year":"2024","key":"e_1_2_9_2_1"},{"volume-title":"Guidelines for the Use of Antiretroviral Agents in Adults and Adolescents With HIV","author":"Panel on Antiretroviral Guidelines for Adults and Adolescents","key":"e_1_2_9_3_1"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0100-40422010000800023"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkab324"},{"volume-title":"StatPearls","year":"2025","author":"Eggleton J. 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