{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T00:47:28Z","timestamp":1777942048904,"version":"3.51.4"},"reference-count":41,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T00:00:00Z","timestamp":1774915200000},"content-version":"vor","delay-in-days":30,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Special Care in Dentistry"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>The aim of the present study was to investigate the prevalence of oral manifestations among patients undergoing chemotherapy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A systematic review was conducted and followed the Preferred Reporting Items for Systematic Reviews and Meta\u2010Analyses. The review was registered in PROSPERO, under registration number CRD42024564007. Two independent reviewers conducted searches in the PubMed, Embase, and Scopus databases as well as Google Scholar for grey literature in July 2024. Inclusion criteria comprised cross\u2010sectional studies that evaluated oral manifestations associated with chemotherapy. Risk of bias was assessed using JBI Critical Appraisal tool for cross\u2010sectional studies. Synthesis of the results was performed using the MedCalc software program.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Twenty\u2010four cross\u2010sectional studies were included. After the analysis of the results, the pooled prevalence was estimated for the following oral manifestations: oral mucositis (42.15%); xerostomia (39.92%); dysgeusia (49.62%); candidiasis (24.11%); oral herpes (7.98%); oral ulcer (31.40%); gingivitis (56.15%); dysphagia (28.28%); halitosis (19.55%); oral pain (22.78%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The evidence suggests that the prevalence oral manifestations is high in patients undergoing chemotherapy. However, the results should be interpreted with caution due to the considerable heterogeneity among the studies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/scd.70168","type":"journal-article","created":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T11:23:46Z","timestamp":1774956226000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Prevalence of Oral Manifestations in Individuals Undergoing Chemotherapy: Systematic Review and Meta\u2010Analysis"],"prefix":"10.1111","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-1368-8718","authenticated-orcid":false,"given":"Valder Ferreira da Silva","family":"Filho","sequence":"first","affiliation":[{"name":"Faculty of Dentistry Faculdade Sete Lagoas (FACSETE) Sete Lagoas Minas Gerais Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-8804-926X","authenticated-orcid":false,"given":"Let\u00edcia Rocha Dias da","family":"Motta","sequence":"additional","affiliation":[{"name":"Faculty of Dentistry Faculdade Sete Lagoas (FACSETE) Sete Lagoas Minas Gerais Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2258-8071","authenticated-orcid":false,"given":"Lucas Guimar\u00e3es","family":"Abreu","sequence":"additional","affiliation":[{"name":"Department of Child and Adolescent Oral Health Federal University of Minas Gerais (UFMG)  Belo Horizonte Minas Gerais Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7286-2206","authenticated-orcid":false,"given":"Leonardo Nogueira","family":"Rodrigues","sequence":"additional","affiliation":[{"name":"Faculty of Dentistry Faculdade Sete Lagoas (FACSETE) Sete Lagoas Minas Gerais Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3028-7095","authenticated-orcid":false,"given":"Nat\u00e1lia Cristina Ruy","family":"Carneiro","sequence":"additional","affiliation":[{"name":"Faculty of Dentistry Faculdade Anhanguera, Unidade Timbiras Belo Horizonte Minas Gerais Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,3,31]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21834"},{"issue":"12","key":"e_1_2_9_3_1","article-title":"Interventions for the Treatment of Oral Cavity and Oropharyngeal Cancer: Chemotherapy","volume":"12","author":"Parmar A.","year":"2021","journal-title":"Cochrane Database of Systematic Reviews"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-021-00572-w"},{"issue":"4","key":"e_1_2_9_5_1","article-title":"Interventions for Preventing Oral Mucositis for Patients With Cancer Receiving Treatment","volume":"2011","author":"Worthington H. 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