{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T15:50:00Z","timestamp":1789487400950,"version":"build-2803163510"},"reference-count":12,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T00:00:00Z","timestamp":1789344000000},"content-version":"vor","delay-in-days":13,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Special Care in Dentistry"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Congenital Insensitivity to Pain with Anhidrosis (CIPA) is a rare, autosomal recessive genetic condition characterized by an inability to sweat, intellectual disability, a lack of pain sensation and self\u2010mutilating behaviours. This report describes the dental management and longitudinal oral findings of a child with CIPA, highlighting a restorative approach and novel findings in the permanent dentition.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A 3\u2010year\u201010\u2010month\u2010old boy presented with severe early childhood caries, premature exfoliation of primary teeth, traumatic tongue biting and recurrent oral ulceration. Comprehensive dental treatment was performed under general anaesthesia, including restorations and extraction of unrestorable primary teeth.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Subsequent follow\u2010up revealed altered eruption sequence, premature eruption and hypomineralisation and hypoplasia of permanent teeth. At 7\u2010year\u20101\u2010month, he developed a large palatal ulcer and swelling associated with a recently exfoliated upper left second molar (#65). Wound debridement, excision of malformed upper left second premolar (#25) and restorative treatment of affected permanent teeth were performed under general anaesthesia. Tooth morphology was modified to reduce soft tissue trauma. Healing was observed 1 month post\u2010operatively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Conservative restorative management may preserve oral function in selected patients with CIPA, while long\u2010term surveillance is essential because of developmental dental anomalies, altered eruption sequence and recurrent traumatic injury.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/scd.70252","type":"journal-article","created":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T11:32:28Z","timestamp":1789385548000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Considerations in Restorative Management and New Oral Findings in a Patient With Congenital Insensitivity to Pain With Anhidrosis"],"prefix":"10.1111","volume":"46","author":[{"given":"Pui Ling","family":"Chay","sequence":"first","affiliation":[{"name":"Dental Service KK Women's and Children's Hospital  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5028-2745","authenticated-orcid":false,"given":"Melissa Mei\u2010Yi","family":"Khor","sequence":"additional","affiliation":[{"name":"Dental Service KK Women's and Children's Hospital  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2851-6987","authenticated-orcid":false,"given":"Boon Hui","family":"Chan","sequence":"additional","affiliation":[{"name":"Dental Service KK Women's and Children's Hospital  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3029-4914","authenticated-orcid":false,"given":"Vanessa Yan Xiu","family":"Kwek","sequence":"additional","affiliation":[{"name":"Dental Service KK Women's and Children's Hospital  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8428-5044","authenticated-orcid":false,"given":"Angela Yun June","family":"Tan","sequence":"additional","affiliation":[{"name":"Department of Paediatrics KK Women's and Children's Hospital  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4514-6869","authenticated-orcid":false,"given":"Koh Ai","family":"Ling","sequence":"additional","affiliation":[{"name":"Department of Paediatric Anaesthesia KK Women's and Children's Hospital  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-5883-2067","authenticated-orcid":false,"given":"Siew Luan","family":"Toh","sequence":"additional","affiliation":[{"name":"Dental Service KK Women's and Children's Hospital  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,14]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2005.07.030"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-9657.2009.00810.x"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1079-2104(98)90368-7"},{"key":"e_1_2_10_5_1","article-title":"Orofacial Manifestations of Congenital Insensitivity to Pain With Anhidrosis: A Report of 24 Cases","volume":"69","author":"Bodner L.","year":"2002","journal-title":"ASDC Journal of Dentistry for Children"},{"key":"e_1_2_10_6_1","first-page":"E644","article-title":"Dental Management of Oral Self\u2010Mutilation in Neurological Patients: A Case of Congenital Insensitivity to Pain With Anhidrosis","volume":"13","author":"Romero M.","year":"2008","journal-title":"Medicina Oral, Patolog\u00eda Oral y Cirug\u00eda 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