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In addition, physical activity seems to be low early in the disease. The aim of this study was to describe the level of <jats:styled-content style=\"fixed-case\">PA<\/jats:styled-content> in patients with stable <jats:styled-content style=\"fixed-case\">COPD<\/jats:styled-content> and to explore factors associated with low <jats:styled-content style=\"fixed-case\">PA<\/jats:styled-content>, with a focus on fatigue, symptom burden and body composition<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In a cross\u2010sectional study, 101 patients (52 women) with <jats:styled-content style=\"fixed-case\">COPD<\/jats:styled-content> were classified having low, moderate or high <jats:styled-content style=\"fixed-case\">PA<\/jats:styled-content> according to the International Physical Activity Questionnaire \u2013 Short. Fatigue, dyspnoea, depression and anxiety, symptom burden, body composition, physical capacity (lung function, exercise capacity, muscle strength), exacerbation rate and systemic inflammation were assessed. A multiple logistic regression was used to identify independent associations with low <jats:styled-content style=\"fixed-case\">PA<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Mean age was 68 (\u00b17) years, and mean percentage of predicted forced expiratory volume in 1\u00a0second was 50 (\u00b116.5). Forty\u2010two patients reported a low <jats:styled-content style=\"fixed-case\">PA<\/jats:styled-content> level, while 34 moderate and 25 reported high levels. Factors independently associated with low <jats:styled-content style=\"fixed-case\">PA<\/jats:styled-content>, presented as odds ratio (95% confidence interval), were severe fatigue 5.87 (1.23\u201328.12), exercise capacity 0.99 (0.99\u20131.0) and the number of pack\u2010years 1.04 (1.01\u20131.07). No relationship was found between depression, anxiety, body composition, exacerbation rate or systemic inflammation and <jats:styled-content style=\"fixed-case\">PA<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Severe fatigue, worse exercise capacity and a higher amount of smoking were independently associated with low <jats:styled-content style=\"fixed-case\">PA<\/jats:styled-content>. Promoting physical activity is important in all patients with <jats:styled-content style=\"fixed-case\">COPD<\/jats:styled-content>. Our result suggests that patients with severe fatigue might need specific strategies to prevent physical inactivity.<\/jats:p><\/jats:sec>","DOI":"10.1111\/scs.12200","type":"journal-article","created":{"date-parts":[[2015,2,4]],"date-time":"2015-02-04T08:48:44Z","timestamp":1423039724000},"page":"697-707","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Factors associated with low physical activity in patients with chronic obstructive pulmonary disease: a cross\u2010sectional study"],"prefix":"10.1111","volume":"29","author":[{"given":"Kristina","family":"T\u00f6dt","sequence":"first","affiliation":[{"name":"Department of Social and Welfare Studies Link\u00f6ping University Norrk\u00f6ping Sweden"},{"name":"Department of Respiratory Medicine and Department of Medical and Health Sciences Link\u00f6ping University Link\u00f6ping 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