{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T04:09:47Z","timestamp":1776744587910,"version":"3.51.2"},"reference-count":47,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2017,9,11]],"date-time":"2017-09-11T00:00:00Z","timestamp":1505088000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100012538","name":"Swedish Cancer Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100012538","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Scandinavian Caring Sciences"],"published-print":{"date-parts":[[2018,6]]},"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p>Lymphoedema may cause complex problems that can strongly influence patients' health\u2010related quality of life (<jats:styled-content style=\"fixed-case\">HRQ<\/jats:styled-content>oL). The main purpose of this study was to investigate the impact of lymphoedema on <jats:styled-content style=\"fixed-case\">HRQ<\/jats:styled-content>oL in patients with varying forms of lymphoedema.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The Lymphoedema Quality of Life Inventory (Ly<jats:styled-content style=\"fixed-case\">QLI<\/jats:styled-content>), measuring three domains, physical, psychosocial and practical, and the Short Form 36 Health Survey Questionnaire (<jats:styled-content style=\"fixed-case\">SF<\/jats:styled-content>\u201036), measuring eight health domains, were sent to 200 lymphoedema patients. Out of those who answered both questionnaires, 88 patients had lymphoedema secondary to cancer treatment and they additionally received the Functional Assessment of Cancer Therapy Scale\u2010General (<jats:styled-content style=\"fixed-case\">FACT<\/jats:styled-content>\u2010G). The relation between continuous variables and the three domains were analysed by Spearman's correlation coefficients, and Kruskal\u2013Wallis test was used to analyse categorical variables.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Altogether 129 patients completed the Ly<jats:styled-content style=\"fixed-case\">QLI<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">SF<\/jats:styled-content>\u201036 and 79 of them also completed <jats:styled-content style=\"fixed-case\">FACT<\/jats:styled-content>\u2010G. Twenty per cent had a high mean score (\u22652.0) in at least one domain of the Ly<jats:styled-content style=\"fixed-case\">QLI<\/jats:styled-content>, thus having a low <jats:styled-content style=\"fixed-case\">HRQ<\/jats:styled-content>oL. Lower <jats:styled-content style=\"fixed-case\">HRQ<\/jats:styled-content>oL was found in the practical domain of Ly<jats:styled-content style=\"fixed-case\">QLI<\/jats:styled-content> in patients with lower limb lymphoedema compared to patient with lymphoedema in upper limb or head\/neck (p = 0.002) and in patients working part\u2010time compared to patients working full\u2010time (p = 0.005). The impact on <jats:styled-content style=\"fixed-case\">HRQ<\/jats:styled-content>oL tended to decrease with age, with a significant correlation in the psychosocial domain (<jats:italic>r<\/jats:italic><jats:sub><jats:italic>s<\/jats:italic><\/jats:sub> = 0.194, p = 0.028). Compared with the general Swedish population, patients with lymphoedema scored significantly lower in general health (p = 0.006), vitality (p = 0.002) and social functioning (p = 0.025) assessed by the <jats:styled-content style=\"fixed-case\">SF<\/jats:styled-content>\u201036. From a cancer\u2010specific view, <jats:styled-content style=\"fixed-case\">HRQ<\/jats:styled-content>oL was similar to other Swedish studies using the <jats:styled-content style=\"fixed-case\">FACT<\/jats:styled-content>\u2010G.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This study indicates that about 20% of the patients with lymphoedema had major impact on their <jats:styled-content style=\"fixed-case\">HRQ<\/jats:styled-content>oL. More effort and research is needed to identify, understand and support groups of patients with severe lymphoedema\u2010related problems.<\/jats:p><\/jats:sec>","DOI":"10.1111\/scs.12488","type":"journal-article","created":{"date-parts":[[2017,9,11]],"date-time":"2017-09-11T15:14:36Z","timestamp":1505142876000},"page":"634-644","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Health\u2010related quality of life in patients with lymphoedema \u2013 a cross\u2010sectional study"],"prefix":"10.1111","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3055-0076","authenticated-orcid":false,"given":"Pia","family":"Klern\u00e4s","sequence":"first","affiliation":[{"name":"Department of Health Sciences Division of Physiotherapy Lund University Sweden"},{"name":"Br\u00e4cke diakoni Rehabcenter Sf\u00e4ren Solna Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aina","family":"Johnsson","sequence":"additional","affiliation":[{"name":"Department of Neurobiology Care Sciences and Society Division of Social Work Karolinska Institutet Stockholm Sweden"},{"name":"Department of Oncology S\u00f6dersjukhuset Stockholm Sweden"},{"name":"Function Area Social Work in Health Karolinska University Hospital Stockholm Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vibeke","family":"Horstmann","sequence":"additional","affiliation":[{"name":"Department of Health Sciences Faculty of Medicine Lund University Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karin","family":"Johansson","sequence":"additional","affiliation":[{"name":"Department of Health Sciences Division of Physiotherapy Lund University Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,9,11]]},"reference":[{"key":"e_1_2_10_2_1","first-page":"84","article-title":"The diagnosis and treatment of peripheral lymphedema. 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