{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T14:42:36Z","timestamp":1787755356477,"version":"build-2784847793"},"reference-count":46,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T00:00:00Z","timestamp":1770768000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T00:00:00Z","timestamp":1770768000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Scandinavian Caring Sciences"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims and Objectives<\/jats:title>\n                    <jats:p>Negative pressure wound therapy with instillation is increasingly used to treat various wounds. However, there is limited information about its impact on patient experiences. This study aims to explore the experiences of hospitalised patients undergoing negative pressure wound therapy with instillation for different types of wounds and to explore their expectations regarding continuing treatment at home.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methodological Design and Justification<\/jats:title>\n                    <jats:p>We conducted a qualitative study using semi\u2010structured interviews. 12 patients treated with negative pressure wound therapy with instillation across various hospitals in the Netherlands were interviewed between January 2024 and June 2024. Data were analysed using Braun and Clarke's reflexive thematic analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Ethical Issues and Approval<\/jats:title>\n                    <jats:p>This study was deemed not subject to the Medical Research Involving Human Subjects Act (WMO), as confirmed by a non\u2010WMO declaration from the ethics committee. All participants provided informed consent prior to the interview.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Seven themes were generated from the data: feeling prepared for negative pressure wound therapy with instillation, gaining trust and hope because of wound healing, having trust in the expertise of nurses, facing fear and dread during negative pressure wound therapy with instillation, dealing with sleep disturbance, having difficulties with daily living activities, and worrying about undergoing negative pressure wound therapy with instillation at home. Although patients initially faced uncertainties, improved wound healing builds trust in the treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Negative pressure wound therapy with instillation significantly impacts patients' physical and emotional well\u2010being. Patients felt more prepared and confident when provided with detailed explanations about the device and what to expect during treatment. Nurses' unfamiliarity with the treatment further diminished patient trust. For optimal patient care, patients require adequate preparation and support from well\u2010trained nurses to manage the physical and emotional impact of negative pressure wound therapy with instillation, in both hospital and home settings.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Reporting Method<\/jats:title>\n                    <jats:p>Adheres to the Reflexive Thematic Analysis Reporting Guidelines.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patient or Public Contribution<\/jats:title>\n                    <jats:p>Patients were involved in the study through interviews.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/scs.70203","type":"journal-article","created":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T07:25:42Z","timestamp":1770881142000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Experiences and Expectations of Hospitalised Patients Undergoing Negative Pressure Wound Therapy With Instillation: A Qualitative Study"],"prefix":"10.1111","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-3337-4652","authenticated-orcid":false,"given":"Annabel","family":"Nanninga","sequence":"first","affiliation":[{"name":"Nursing Sciences, Program in Clinical Health Sciences University Medical Center Utrecht, Utrecht University  Utrecht the Netherlands"},{"name":"Department of Imaging and Oncology University Medical Center Utrecht  Utrecht the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heleen","family":"Westland","sequence":"additional","affiliation":[{"name":"Julius Center for Health Sciences and Primary Care University Medical Center Utrecht  Utrecht the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricardo G.","family":"Orsini","sequence":"additional","affiliation":[{"name":"Department of Surgery Maastricht University Medical Center+  Maastricht the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marja A.","family":"Boermeester","sequence":"additional","affiliation":[{"name":"Department of Surgery Amsterdam UMC Location University of Amsterdam  Amsterdam the Netherlands"},{"name":"Amsterdam Gastroenterology Endocrinology &amp; Metabolism  Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne M.","family":"Eskes","sequence":"additional","affiliation":[{"name":"Department of Surgery Amsterdam UMC Location University of Amsterdam  Amsterdam the Netherlands"},{"name":"Amsterdam Public Health  Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-5264-6716","authenticated-orcid":false,"given":"Hannah","family":"Groenen","sequence":"additional","affiliation":[{"name":"Department of Surgery Amsterdam UMC Location University of Amsterdam  Amsterdam the Netherlands"},{"name":"Amsterdam Gastroenterology Endocrinology &amp; Metabolism  Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,2,11]]},"reference":[{"key":"e_1_2_15_2_1","volume-title":"Complex Wound Management","author":"Labib A.","year":"2025"},{"key":"e_1_2_15_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/iwj.14128"},{"key":"e_1_2_15_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/WON.0000000000000824"},{"key":"e_1_2_15_5_1","volume-title":"Quality of Life","author":"Teoli D.","year":"2025"},{"key":"e_1_2_15_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/00207640211032259"},{"key":"e_1_2_15_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/iwj.13254"},{"issue":"10","key":"e_1_2_15_8_1","first-page":"309","article-title":"Negative Pressure Wound Therapy With Controlled Saline Instillation (NPWTi): Dressing Properties and Granulation Response In\u00a0Vivo","volume":"23","author":"Lessing C.","year":"2011","journal-title":"Wounds"},{"key":"e_1_2_15_9_1","doi-asserted-by":"publisher","DOI":"10.12968\/jowc.2017.26.Sup3.S1"},{"issue":"6","key":"e_1_2_15_10_1","first-page":"609","article-title":"Use of Negative Pressure Wound Therapy With Instillation and Dwell Time for Wound Treatment \u2010 Results of an Expert Consensus Conference","volume":"143","author":"Horch R. E.","year":"2018","journal-title":"Zentralblatt f\u00fcr Chirurgie"},{"key":"e_1_2_15_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/iwj.14072"},{"key":"e_1_2_15_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/burnst\/tkab046"},{"issue":"3","key":"e_1_2_15_13_1","article-title":"Feeling Confident in Burdensome Yet Enriching Care: Community Nurses Describe the Care of Patients With Hard\u2010To\u2010Heal Wounds","volume":"5","author":"Eskilsson C.","year":"2010","journal-title":"QHW"},{"key":"e_1_2_15_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0000000000009232"},{"key":"e_1_2_15_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/iwj.13989"},{"key":"e_1_2_15_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/iwj.12913"},{"key":"e_1_2_15_17_1","doi-asserted-by":"publisher","DOI":"10.12968\/jowc.2013.22.1.34"},{"key":"e_1_2_15_18_1","doi-asserted-by":"publisher","DOI":"10.12968\/jowc.2016.25.3.154"},{"key":"e_1_2_15_19_1","doi-asserted-by":"publisher","DOI":"10.12968\/jowc.2020.29.4.206"},{"key":"e_1_2_15_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/nop2.1392"},{"key":"e_1_2_15_21_1","article-title":"Nurses' Challenges in Wound Care Management\u2010A Qualitative Study","volume":"15","author":"Tayyib N. A.","year":"2021","journal-title":"Journal of Clinical and Diagnostic Research"},{"key":"e_1_2_15_22_1","doi-asserted-by":"publisher","DOI":"10.1177\/02692163241234800"},{"key":"e_1_2_15_23_1","doi-asserted-by":"publisher","DOI":"10.11648\/j.ajtas.20160501.11"},{"key":"e_1_2_15_24_1","volume-title":"An Introduction to Qualitative Research","author":"Flick U.","year":"2022"},{"key":"e_1_2_15_25_1","doi-asserted-by":"publisher","DOI":"10.1177\/1534734620946577"},{"key":"e_1_2_15_26_1","unstructured":"VERBI Software \u201cMAXQDA 2022 \u201d(2021) https:\/\/www.maxqda.com\/."},{"key":"e_1_2_15_27_1","unstructured":"The World Medical Association INC \u201cDeclaration of Helsinki Ethical Principles for Medical Research Involving Human Subjects \u201d(2008)."},{"key":"e_1_2_15_28_1","unstructured":"Medical Research Involving Human Subjects Act (WMO) \u201cCentral Committee on Research Involving Human Subjects \u201d(2023)."},{"key":"e_1_2_15_29_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12909-019-1922-2"},{"key":"e_1_2_15_30_1","doi-asserted-by":"publisher","DOI":"10.12968\/bjon.2010.19.Sup10.79692"},{"key":"e_1_2_15_31_1","doi-asserted-by":"publisher","DOI":"10.4236\/ojn.2015.53024"},{"issue":"8","key":"e_1_2_15_32_1","first-page":"1049","article-title":"Insomnia Complaints and Perceived Immune Fitness in Young Adults With and Without Self\u2010Reported Impaired Wound Healing","volume":"58","author":"Balikji J.","year":"2022","journal-title":"Medicine"},{"key":"e_1_2_15_33_1","doi-asserted-by":"publisher","DOI":"10.1177\/15347346221077571"},{"issue":"4","key":"e_1_2_15_34_1","first-page":"58","article-title":"The Importance of Patient Wellbeing","volume":"11","author":"Hussey G.","year":"2020","journal-title":"Wounds International"},{"key":"e_1_2_15_35_1","doi-asserted-by":"publisher","DOI":"10.1111\/jocn.13702"},{"key":"e_1_2_15_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijnss.2020.11.003"},{"key":"e_1_2_15_37_1","doi-asserted-by":"publisher","DOI":"10.12968\/jowc.2023.32.7.437"},{"key":"e_1_2_15_38_1","doi-asserted-by":"publisher","DOI":"10.1111\/iwj.12059"},{"key":"e_1_2_15_39_1","doi-asserted-by":"publisher","DOI":"10.1002\/nop2.2107"},{"key":"e_1_2_15_40_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ASW.0000658572.14692.fb"},{"key":"e_1_2_15_41_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ASW.0000753256.29578.6c"},{"key":"e_1_2_15_42_1","volume-title":"Assisting Patients With Mobility","author":"Javed M. J.","year":"2024"},{"key":"e_1_2_15_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2024.04.014"},{"key":"e_1_2_15_44_1","doi-asserted-by":"publisher","DOI":"10.1111\/wrr.70059"},{"key":"e_1_2_15_45_1","volume-title":"Thematic Analysis: A Practical Guide","author":"Braun V.","year":"2021"},{"key":"e_1_2_15_46_1","doi-asserted-by":"publisher","DOI":"10.1177\/1473325015585613"},{"key":"e_1_2_15_47_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurjcn\/zvab038"}],"container-title":["Scandinavian Journal of Caring Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/scs.70203","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/scs.70203","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/scs.70203","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T22:42:00Z","timestamp":1774564920000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/scs.70203"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,11]]},"references-count":46,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,3]]}},"alternative-id":["10.1111\/scs.70203"],"URL":"https:\/\/doi.org\/10.1111\/scs.70203","archive":["Portico"],"relation":{},"ISSN":["0283-9318","1471-6712"],"issn-type":[{"value":"0283-9318","type":"print"},{"value":"1471-6712","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,11]]},"assertion":[{"value":"2025-08-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-21","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-11","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70203"}}