{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T16:18:29Z","timestamp":1764173909823},"reference-count":19,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2013,2,14]],"date-time":"2013-02-14T00:00:00Z","timestamp":1360800000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Seminars in Dialysis"],"published-print":{"date-parts":[[2013,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Disruption of blood brain barrier (BBB) with subsequent subarachnoid contrast extravasation and cerebral edema is a rare complication of intra\u2010arterial contrast administration. We report a patient with end\u2010stage renal disease (ESRD) who developed such a complication. A 63\u2010year\u2010old man with a history of left orbital apex syndrome on hemodialysis (HD) was admitted with massive epistaxis. A pseudo\u2010aneurysm of the left internal carotid artery (ICA) required a cerebral arteriogram with coil embolization; a total of 910\u2003ml of isosmolar intra\u2010arterial contrast was used. Shortly thereafter, the patient developed severe alteration in his mental status. A CT study without contrast of the head showed bilateral subarachnoid hyper\u2010attenuation with diffuse cerebral edema consistent with contrast\u2010induced encephalopathy syndrome. The patient was urgently and repetitively dialyzed to remove the contrast leading to a remarkable improvement in his mental status and resolution of both subarachnoid hyper\u2010attenuation and brain edema. The large volume of intra\u2010arterial contrast that may be required in neurologic interventional procedures is occasionally associated with breakdown of BBB leading to subarachnoid accumulation and cerebral edema resulting in a severe encephalopathy syndrome. Hemodialysis seems particularly well suited for the patient who has renal failure in whom this syndrome develops.<\/jats:p>","DOI":"10.1111\/sdi.12061","type":"journal-article","created":{"date-parts":[[2013,2,14]],"date-time":"2013-02-14T08:03:51Z","timestamp":1360829031000},"page":"203-207","source":"Crossref","is-referenced-by-count":15,"title":["Severe Encephalopathy Following Cerebral Arteriogram in a Patient with End\u2010Stage Renal Disease"],"prefix":"10.1111","volume":"26","author":[{"given":"Jingyin","family":"Yan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Venkat","family":"Ramanathan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,2,14]]},"reference":[{"key":"e_1_2_4_2_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10072-011-0765-3"},{"key":"e_1_2_4_3_2","doi-asserted-by":"publisher","DOI":"10.3340\/jkns.2011.50.1.45"},{"key":"e_1_2_4_4_2","doi-asserted-by":"publisher","DOI":"10.3340\/jkns.2010.48.6.524"},{"key":"e_1_2_4_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00270-009-9609-4"},{"key":"e_1_2_4_6_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3181d9ed46"},{"key":"e_1_2_4_7_2","first-page":"1783","article-title":"Blood brain\u2010barrier disruption of nonionic iodinated contrast medium following coil embolization of a ruptured intracerebral aneurysm","volume":"25","author":"Uchiyama Y","year":"2004","journal-title":"AJNR Am J Neuroradiol"},{"key":"e_1_2_4_8_2","doi-asserted-by":"publisher","DOI":"10.1159\/000070198"},{"key":"e_1_2_4_9_2","first-page":"1114","article-title":"Cortical blindness after contrast\u2010enhanced CT: complication in a patient with diabetes insipidus","volume":"24","author":"Mentzel HJ","year":"2003","journal-title":"AJNR Am J Neuroradiol"},{"key":"e_1_2_4_10_2","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.170.2.9456974"},{"key":"e_1_2_4_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/0895-6111(95)00008-E"},{"key":"e_1_2_4_12_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.59.5.851"},{"key":"e_1_2_4_13_2","first-page":"249","article-title":"Transient cortical blindness and convulsion mimicking a hemorrhagic complication during embolization of the cerebellar AVM","volume":"27","author":"Nakai Y","year":"1999","journal-title":"No Shinkei Geka"},{"key":"e_1_2_4_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)78557-3"},{"key":"e_1_2_4_15_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2009.08.016"},{"key":"e_1_2_4_16_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11604-006-0030-5"},{"key":"e_1_2_4_17_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ki.5000371"},{"key":"e_1_2_4_18_2","doi-asserted-by":"crossref","first-page":"3026","DOI":"10.1007\/s00330-002-1629-2","article-title":"Dialysis and contrast media","volume":"12","author":"Morcos SK","year":"2002","journal-title":"Eur Radiol"},{"key":"e_1_2_4_19_2","doi-asserted-by":"publisher","DOI":"10.1080\/02841859809172447"},{"key":"e_1_2_4_20_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-139X.2007.00233.x"}],"container-title":["Seminars in Dialysis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fsdi.12061","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/sdi.12061","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,28]],"date-time":"2023-10-28T15:41:32Z","timestamp":1698507692000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/sdi.12061"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,2,14]]},"references-count":19,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2013,3]]}},"alternative-id":["10.1111\/sdi.12061"],"URL":"https:\/\/doi.org\/10.1111\/sdi.12061","archive":["Portico"],"relation":{},"ISSN":["0894-0959","1525-139X"],"issn-type":[{"value":"0894-0959","type":"print"},{"value":"1525-139X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,2,14]]}}}