{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T17:13:21Z","timestamp":1789751601410,"version":"4.0.1"},"reference-count":42,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2014,9,12]],"date-time":"2014-09-12T00:00:00Z","timestamp":1410480000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Seminars in Dialysis"],"published-print":{"date-parts":[[2015,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Patients with end\u2010stage renal disease are more likely to suffer from gastrointestinal (<jats:styled-content style=\"fixed-case\">GI<\/jats:styled-content>) problems, including bleeding from upper and lower sources. Peptic ulcer disease is the most common cause of upper <jats:styled-content style=\"fixed-case\">GI<\/jats:styled-content> bleeding, and although there is some debate in the literature regarding whether the frequency of ulcer disease is higher in patients with kidney disease, it is well established that outcomes are worse in patients with compromised renal function. Angioectasias can be found throughout the <jats:styled-content style=\"fixed-case\">GI<\/jats:styled-content> tract and are another common cause of bleeding; management can be divided into localized endoscopic therapy and systemic hormonal treatment, or surgery for refractory cases. The most frequent causes of lower <jats:styled-content style=\"fixed-case\">GI<\/jats:styled-content> bleeding in this population, in addition to angioectasias, are diverticulosis, hemorrhoids, and ischemic colitis.<\/jats:p>","DOI":"10.1111\/sdi.12301","type":"journal-article","created":{"date-parts":[[2014,9,12]],"date-time":"2014-09-12T11:04:32Z","timestamp":1410519872000},"page":"68-74","source":"Crossref","is-referenced-by-count":49,"title":["Evidence\u2010based Review of Gastrointestinal Bleeding in the Chronic Kidney Disease Patient"],"prefix":"10.1111","volume":"28","author":[{"given":"Richard S.","family":"Kalman","sequence":"first","affiliation":[{"name":"Section of Gastroenterology Department of Medicine Boston University Medical Center Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcos C.","family":"Pedrosa","sequence":"additional","affiliation":[{"name":"Section of Gastroenterology Department of Medicine VA Boston Healthcare System Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,9,12]]},"reference":[{"issue":"8","key":"e_1_2_5_2_1","first-page":"287","article-title":"Chronic gastrointestinal symptoms in hemodialysis patients","volume":"110","author":"Hammer J","year":"1998","journal-title":"Wien Klin Wochenschr"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(83)90341-8"},{"issue":"11","key":"e_1_2_5_4_1","first-page":"2329","article-title":"Lower gastrointestinal bleeding in chronic hemodialysis patients","volume":"91","author":"Saeed F","year":"2011","journal-title":"Int J Nephrol"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.2003.00225.x"},{"issue":"11","key":"e_1_2_5_6_1","first-page":"2329","article-title":"Upper gastrointestinal bleeding in patients with chronic renal failure: role of vascular ectasia","volume":"91","author":"Chalasani N","year":"1996","journal-title":"Am J Gastroenterol"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2011070658"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01550962"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/ki.2008.508"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.38.3.316"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2009.04.014"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2011.480"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2009.115"},{"issue":"20","key":"e_1_2_5_14_1","doi-asserted-by":"crossref","first-page":"2321","DOI":"10.1001\/archinte.1996.00440190069008","article-title":"Prevention of nonsteroidal anti\u2010inflammatory drug\u2010induced gastrointestinal mucosal injury. A meta\u2010analysis of randomized controlled clinical trials","volume":"156","author":"Koch M","year":"1996","journal-title":"Arch Intern Med"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1985.00360030098019"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-102-5-588"},{"key":"e_1_2_5_17_1","first-page":"564","article-title":"Prevalence and natural history of colonic angiodysplasia among healthy asymptomatic people","volume":"90","author":"Foutch PG","year":"1995","journal-title":"Am J Gastroenterol"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5107(04)02221-7"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1952.02930320016006"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1155\/2006\/859435"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-105-3-371"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1097\/00042737-199306000-00008"},{"key":"e_1_2_5_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.1998.404_i.x"},{"key":"e_1_2_5_24_1","doi-asserted-by":"publisher","DOI":"10.1053\/gast.2001.28650"},{"key":"e_1_2_5_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2007.01053.x"},{"key":"e_1_2_5_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-010-1193-6"},{"key":"e_1_2_5_27_1","doi-asserted-by":"publisher","DOI":"10.1097\/MEG.0b013e32832c9346"},{"key":"e_1_2_5_28_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2011.07.018"},{"key":"e_1_2_5_29_1","first-page":"1","article-title":"\u201cDownhill\u201d esophageal varices due to dialysis catheter\u2010induced superior vena caval occlusion: a rare cause of upper gastrointestinal bleeding","volume":"830796","author":"Nayudu SK","year":"2013","journal-title":"Case Rep Gastrointest Med"},{"key":"e_1_2_5_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0889-8553(21)00179-5"},{"key":"e_1_2_5_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.21907"},{"issue":"6","key":"e_1_2_5_32_1","first-page":"807","article-title":"Angiodysplasia of the gastrointestinal tract","volume":"88","author":"Foutch PG","year":"1993","journal-title":"Am J Gastroenterol"},{"key":"e_1_2_5_33_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004836-198408000-00001"},{"key":"e_1_2_5_34_1","doi-asserted-by":"publisher","DOI":"10.1097\/MCG.0b013e3181862ad1"},{"key":"e_1_2_5_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5107(97)70130-5"},{"key":"e_1_2_5_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5107(98)70115-4"},{"key":"e_1_2_5_37_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2000.01644.x"},{"key":"e_1_2_5_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0039-6060(03)00308-8"},{"key":"e_1_2_5_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-4804(89)90059-0"},{"key":"e_1_2_5_40_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-195002000-00003"},{"key":"e_1_2_5_41_1","doi-asserted-by":"publisher","DOI":"10.1038\/ki.1996.313"},{"key":"e_1_2_5_42_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11894-013-0332-6"},{"key":"e_1_2_5_43_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1797.2009.01274.x"}],"container-title":["Seminars in Dialysis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fsdi.12301","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fsdi.12301","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/sdi.12301","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T23:36:57Z","timestamp":1696203417000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/sdi.12301"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,9,12]]},"references-count":42,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2015,1]]}},"alternative-id":["10.1111\/sdi.12301"],"URL":"https:\/\/doi.org\/10.1111\/sdi.12301","archive":["Portico"],"relation":{},"ISSN":["0894-0959","1525-139X"],"issn-type":[{"value":"0894-0959","type":"print"},{"value":"1525-139X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,9,12]]}}}