{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T07:15:03Z","timestamp":1792653303257,"version":"4.5.0"},"reference-count":10,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2015,7,17]],"date-time":"2015-07-17T00:00:00Z","timestamp":1437091200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Seminars in Dialysis"],"published-print":{"date-parts":[[2015,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Current models of animal arteriovenous fistula (<jats:styled-content style=\"fixed-case\">AVF<\/jats:styled-content>) are swine models of femoral vein terminolaterally anastomosed to femoral artery, creating a deep <jats:styled-content style=\"fixed-case\">AVF<\/jats:styled-content>. This feature sets it aside from human <jats:styled-content style=\"fixed-case\">AVF<\/jats:styled-content>s using superficial veins. Our <jats:styled-content style=\"fixed-case\">AVF<\/jats:styled-content> model uses sheep superficial veins to create an <jats:styled-content style=\"fixed-case\">AVF<\/jats:styled-content> almost identical to human model. <jats:styled-content style=\"fixed-case\">AVF<\/jats:styled-content>s were created in six sheep using basilic veins sutured terminolaterally to brachial artery. Presurgery vein and artery diameters were measured. We measured <jats:styled-content style=\"fixed-case\">AVF<\/jats:styled-content>s and feeding arteries blood flows and diameters at 1, 3, and 5\u00a0weeks postsurgery. At 5\u00a0weeks we performed angiograms, euthanized animals, and harvested <jats:styled-content style=\"fixed-case\">AVF<\/jats:styled-content>s. Four animals completed the study. Three <jats:styled-content style=\"fixed-case\">AVF<\/jats:styled-content>s developed and were patent at 5\u00a0weeks; one thrombosed. Animal weight and presurgery vessels diameters predicted <jats:styled-content style=\"fixed-case\">AVF<\/jats:styled-content>s blood flows and diameters. Despite using vessels with diameters smaller than the ones recommended for human <jats:styled-content style=\"fixed-case\">AVF<\/jats:styled-content>, the Fistulas developed. Two animals died before the study conclusion for causes unrelated to surgery. This <jats:styled-content style=\"fixed-case\">AVF<\/jats:styled-content> model is anatomically almost identical to the human <jats:styled-content style=\"fixed-case\">AVF<\/jats:styled-content> and has a good maturation rate. It is a viable model for studying <jats:styled-content style=\"fixed-case\">AVF<\/jats:styled-content> maturation, devices intended to improve <jats:styled-content style=\"fixed-case\">AVF<\/jats:styled-content> maturation, <jats:styled-content style=\"fixed-case\">AVF<\/jats:styled-content> related procedures and can even support hemodialysis needles.<\/jats:p>","DOI":"10.1111\/sdi.12407","type":"journal-article","created":{"date-parts":[[2015,7,17]],"date-time":"2015-07-17T07:41:11Z","timestamp":1437118871000},"page":"687-691","source":"Crossref","is-referenced-by-count":8,"title":["Sheep Model of Hemodialysis Arteriovenous Fistula Using Superficial Veins"],"prefix":"10.1111","volume":"28","author":[{"given":"Marius C.","family":"Florescu","sequence":"first","affiliation":[{"name":"Section\u00a0of Nephrology University of Nebraska Medical Center Omaha Nebraska"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kirk W.","family":"Foster","sequence":"additional","affiliation":[{"name":"Pathology Department University of Nebraska Medical Center Omaha Nebraska"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew R.","family":"Sacks","sequence":"additional","affiliation":[{"name":"Section\u00a0of Nephrology University of Nebraska Medical Center Omaha Nebraska"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Lof","sequence":"additional","affiliation":[{"name":"Large Animal Laboratory University of Nebraska Medical Center Omaha Nebraska"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth A.","family":"Stolze","sequence":"additional","affiliation":[{"name":"Large Animal Laboratory University of Nebraska Medical Center Omaha Nebraska"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gretchen M.","family":"Fry","sequence":"additional","affiliation":[{"name":"Large Animal Laboratory University of Nebraska Medical Center Omaha Nebraska"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Derek P.","family":"Bumgardner","sequence":"additional","affiliation":[{"name":"Large Animal Laboratory University of Nebraska Medical Center Omaha Nebraska"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tara","family":"Tysinger","sequence":"additional","affiliation":[{"name":"Vascular Laboratory University of Nebraska Medical Center Omaha Nebraska"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melanie J.","family":"Kuchta","sequence":"additional","affiliation":[{"name":"Vascular Laboratory University of Nebraska Medical Center Omaha Nebraska"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henry J.","family":"Runge","sequence":"additional","affiliation":[{"name":"UNEMED University of Nebraska Medical Center Omaha Nebraska"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William B.","family":"Hadley","sequence":"additional","affiliation":[{"name":"UNEMED University of Nebraska Medical Center Omaha Nebraska"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael C.","family":"Morris","sequence":"additional","affiliation":[{"name":"Section\u00a0of Kidney and Pancreas Transplant Surgery University of Nebraska Medical Center Omaha Nebraska"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,7,17]]},"reference":[{"key":"e_1_2_8_2_1","first-page":"S1","article-title":"KDOQI clinical practice guidelines and clinical practice recommendations for 2006 updates: hemodialysis adequacy, peritoneal dialysis adequacy and vascular access","volume":"48","author":"Besarab A","year":"2006","journal-title":"Am J Kidney 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