{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,4]],"date-time":"2026-03-04T10:44:09Z","timestamp":1772621049961,"version":"3.50.1"},"reference-count":20,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2015,11,9]],"date-time":"2015-11-09T00:00:00Z","timestamp":1447027200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Seminars in Dialysis"],"published-print":{"date-parts":[[2016,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Extracorporeal treatments (<jats:styled-content style=\"fixed-case\">ECTR<\/jats:styled-content>s) such as hemodialysis (<jats:styled-content style=\"fixed-case\">HD<\/jats:styled-content>), enhance the elimination of a small number of toxins. Changes in overdose trends, prescribing practices, antidotes, and dialysis techniques may alter the indications and rates of <jats:styled-content style=\"fixed-case\">ECTR<\/jats:styled-content> use over time. This study analyzed trends in <jats:styled-content style=\"fixed-case\">ECTR<\/jats:styled-content> for poisonings in four countries. A retrospective study of national poison center databases from the United States, Denmark, United Kingdom, and five regional databases within Canada was performed. All cases of patients receiving an <jats:styled-content style=\"fixed-case\">ECTR<\/jats:styled-content> were included. <jats:styled-content style=\"fixed-case\">ECTR<\/jats:styled-content> cases were totalled annually and reported as annual rates per 100,000 exposures with stratification per types of <jats:styled-content style=\"fixed-case\">ECTR<\/jats:styled-content> and toxins. The data collection varied by countries. United States, 1985\u20132014; United Kingdom, 2011\u20132013; Denmark, 2005\u20132014, and regions of Canada as follows: Alberta, 1991\u20132015; Saskatchewan, 2001\u20132015; Nova Scotia\u2010<jats:styled-content style=\"fixed-case\">PEI<\/jats:styled-content>, 2006\u20132015; Quebec, 2008\u20132014; Ontario\u2010Manitoba, 2009\u20132015; British Columbia, 2012\u20132015. During the study period, the total number of <jats:styled-content style=\"fixed-case\">ECTR<\/jats:styled-content>s and rates per 100,000 exposures, respectively, were: United States, 40,258 and 65.7; United Kingdom, 343 and 232.6; Denmark, 616 and 305.5; Canada, 2709 and 177.5; case rates increased over time for the United States, Denmark, and Canada, but decreased in the United Kingdom. Across the <jats:styled-content style=\"fixed-case\">United States<\/jats:styled-content> and Denmark, <jats:styled-content style=\"fixed-case\">HD<\/jats:styled-content> was the preferred modality used. Toxins for which <jats:styled-content style=\"fixed-case\">ECTR<\/jats:styled-content> was most often used were: United States, ethylene glycol; Canada, methanol; United Kingdom, ethylene glycol; Denmark, salicylates. A high number of <jats:styled-content style=\"fixed-case\">ECTR<\/jats:styled-content>s were performed for atypical toxins such as acetaminophen and benzodiazepines. These data demonstrate a growing use of <jats:styled-content style=\"fixed-case\">HD<\/jats:styled-content> for poisoning with significant regional variations in the overall rates and indications.<\/jats:p>","DOI":"10.1111\/sdi.12448","type":"journal-article","created":{"date-parts":[[2015,11,9]],"date-time":"2015-11-09T10:32:43Z","timestamp":1447065163000},"page":"71-80","source":"Crossref","is-referenced-by-count":39,"title":["Practice Trends in the Use of Extracorporeal Treatments for Poisoning in Four Countries"],"prefix":"10.1111","volume":"29","author":[{"given":"Marc","family":"Ghannoum","sequence":"first","affiliation":[{"name":"Department of Nephrology Verdun Hospital University of Montreal Montreal QC Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valery","family":"Lavergne","sequence":"additional","affiliation":[{"name":"Department of Medical Biology Sacr\u00e9\u2010Coeur Hospital University of Montreal Montreal QC Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sophie","family":"Gosselin","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine McGill University Health Centre Centre Anti\u2010Poison du Quebec McGill University Montreal QC Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James B.","family":"Mowry","sequence":"additional","affiliation":[{"name":"Indiana Poison Center Indiana University Health Indianapolis Indiana"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lotte C. G.","family":"Hoegberg","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology The Danish Poisons Information Center Copenhagen University Hospital Bispebjerg Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark","family":"Yarema","sequence":"additional","affiliation":[{"name":"Poison and Drug Information Service Alberta Health Services Calgary Alberta Canada"},{"name":"Department of Emergency Medicine University of Calgary Calgary Alberta Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margaret","family":"Thompson","sequence":"additional","affiliation":[{"name":"Ontario &amp; Manitoba Poison Centres and Divisions Clinical Pharmacology and Emergency Medicine University of Toronto Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nancy","family":"Murphy","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Dalhousie University and IWK Regional Poison Centre Halifax Nova Scotia Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Thompson","sequence":"additional","affiliation":[{"name":"National Poisons Information Service Cardiff and Vale University Health Board Cardiff United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roy","family":"Purssell","sequence":"additional","affiliation":[{"name":"British Columbia Drug and Poison Information Centre Department of Emergency Medicine University of British Columbia Vancouver British Columbia Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert S.","family":"Hoffman","sequence":"additional","affiliation":[{"name":"Division of Medical Toxicology Ronald O. Perelman Department of Emergency Medicine New York University School of Medicine New York City New York"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,11,9]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.annemergmed.2015.03.031"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.10021014"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000000708"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.3109\/15563650.2015.1014907"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.3109\/15563650.2014.973572"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.3109\/15563650.2015.1035441"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2014.04.031"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.3109\/15563650.2014.946994"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000001002"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/ki.2008.462"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.3109\/15563659809028940"},{"key":"e_1_2_7_13_1","first-page":"1169","article-title":"Comparative evaluation of methods of extracorporeal detoxification in acute carbamazepine poisoning","volume":"12","author":"Maslov OG","year":"2011","journal-title":"Klinicheskaia Toksikologiia"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1553-2712.1997.tb03758.x"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/sdi.12246"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2006.04.080"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0087568"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2009.01.016"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/sdi.12238"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.3109\/15563650.2014.987397"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/sdi.12237"}],"container-title":["Seminars in Dialysis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fsdi.12448","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/sdi.12448","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,26]],"date-time":"2023-09-26T04:22:49Z","timestamp":1695702169000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/sdi.12448"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,11,9]]},"references-count":20,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2016,1]]}},"alternative-id":["10.1111\/sdi.12448"],"URL":"https:\/\/doi.org\/10.1111\/sdi.12448","archive":["Portico"],"relation":{},"ISSN":["0894-0959","1525-139X"],"issn-type":[{"value":"0894-0959","type":"print"},{"value":"1525-139X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,11,9]]}}}