{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T09:29:47Z","timestamp":1773221387184,"version":"3.50.1"},"reference-count":13,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2016,4,15]],"date-time":"2016-04-15T00:00:00Z","timestamp":1460678400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Seminars in Dialysis"],"published-print":{"date-parts":[[2016,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Calciphylaxis, a disorder of dermal arteriolar calcification with a distinct predilection for patients with advanced kidney disease, remains an enigmatic condition that challenges clinicians. Observations regarding positive associations between levels of circulating parathyroid hormone (<jats:styled-content style=\"fixed-case\">PTH<\/jats:styled-content>) and the risk of calciphylaxis, combined with experimental data suggesting a pathogenic role of secondary hyperparathyroidism in vascular calcification, have led to the assumption that reducing <jats:styled-content style=\"fixed-case\">PTH<\/jats:styled-content> levels will improve the outcomes in patients with calciphylaxis. This editorial communicates the contemporary data regarding surgical parathyroidectomy as a treatment option for these patients. We raise concerns regarding the quality of available data and discuss the direction of future comparative effectiveness research in this field.<\/jats:p>","DOI":"10.1111\/sdi.12502","type":"journal-article","created":{"date-parts":[[2016,4,15]],"date-time":"2016-04-15T14:06:46Z","timestamp":1460729206000},"page":"312-314","source":"Crossref","is-referenced-by-count":23,"title":["We Do Too Many Parathyroidectomies for Calciphylaxis"],"prefix":"10.1111","volume":"29","author":[{"given":"Sagar U.","family":"Nigwekar","sequence":"first","affiliation":[{"name":"Division of Nephrology Massachusetts General Hospital Boston Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stuart M.","family":"Sprague","sequence":"additional","affiliation":[{"name":"Division of Nephrology and Hypertension NorthShore University HealthSystem University of Chicago Pritzker School of Medicine Evanston Illinois"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,4,15]]},"reference":[{"key":"e_1_2_2_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMe048048"},{"key":"e_1_2_2_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1205624"},{"key":"e_1_2_2_4_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2015.01.034"},{"key":"e_1_2_2_5_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.00320113"},{"key":"e_1_2_2_6_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.134.3493.1876"},{"key":"e_1_2_2_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1976.03630110043012"},{"key":"e_1_2_2_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1983.tb03996.x"},{"key":"e_1_2_2_9_1","doi-asserted-by":"publisher","DOI":"10.1245\/ASO.2006.03.042"},{"key":"e_1_2_2_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2006.08.065"},{"key":"e_1_2_2_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2009.09.022"},{"key":"e_1_2_2_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2011.06.009"},{"key":"e_1_2_2_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/hdi.12087"},{"key":"e_1_2_2_14_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.03520414"}],"container-title":["Seminars in Dialysis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fsdi.12502","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/sdi.12502","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,26]],"date-time":"2023-09-26T04:06:59Z","timestamp":1695701219000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/sdi.12502"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,4,15]]},"references-count":13,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2016,7]]}},"alternative-id":["10.1111\/sdi.12502"],"URL":"https:\/\/doi.org\/10.1111\/sdi.12502","archive":["Portico"],"relation":{},"ISSN":["0894-0959","1525-139X"],"issn-type":[{"value":"0894-0959","type":"print"},{"value":"1525-139X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,4,15]]}}}