{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T03:04:05Z","timestamp":1773716645583,"version":"3.50.1"},"reference-count":41,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,1,2]],"date-time":"2017-01-02T00:00:00Z","timestamp":1483315200000},"content-version":"vor","delay-in-days":1,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000062","name":"National Institute of Diabetes and Digestive and Kidney Diseases","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Seminars in Dialysis"],"published-print":{"date-parts":[[2017,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The association between higher ultrafiltration rates and poor outcomes in hemodialysis patients has received increased attention, to the point that various regulatory entities are considering adding ultrafiltration rate as a quality measure to be monitored and controlled. Most of the discussion to date has focused on ultrafiltration rate scaled to body weight, or more correctly, body mass (ml\/hour per kg). One outcome study suggests that ultrafiltration rate might best be not scaled at all to body size, as modestly higher ultrafiltration rate in very small\u2010size patients may be associated with some survival benefit, probably via increased dietary intake. Outcomes studies also suggest that the risk of exceeding a weight\u2010scaled ultrafiltration target may be magnified in very large patients, and that body weight\u2010scaled ultrafiltration targets in such patients should be set a lower level. Here, we present an analysis, based on physiological hemodynamic arguments, that it would be better to scale ultrafiltration rate to body surface area rather than to body mass. Whatever ultrafiltration rate is scaled to, attempts to restrict ultrafiltration rate by limiting interdialytic weight gain in small, possibly malnourished patients, should be done cautiously, to prevent an inadvertent lowering of intake of calories and dietary protein.<\/jats:p>","DOI":"10.1111\/sdi.12563","type":"journal-article","created":{"date-parts":[[2017,1,8]],"date-time":"2017-01-08T02:27:42Z","timestamp":1483842462000},"page":"15-19","source":"Crossref","is-referenced-by-count":18,"title":["Hemodialysis Ultrafiltration Rate Targets Should Be Scaled to Body Surface Area Rather than to Body Weight"],"prefix":"10.1111","volume":"30","author":[{"given":"John T.","family":"Daugirdas","sequence":"first","affiliation":[{"name":"Department of Medicine Division of Nephrology University of Illinois at Chicago Chicago Illinois"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Schneditz","sequence":"additional","affiliation":[{"name":"Institute of Physiology Medical University of Graz Graz Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,1,2]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ki.5000186"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfm466"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/ki.2010.383"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0272-6386(00)70305-2"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.06340710"},{"key":"e_1_2_7_7_1","first-page":"20A","article-title":"Body size and gender dependent differences in mortality risks associated with ultrafiltration rates","volume":"25","author":"Larkin JW","year":"2014","journal-title":"J Am Soc Nephrol"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2016.06.020"},{"key":"e_1_2_7_9_1","first-page":"324A","article-title":"Association of ultrafiltration rate with mortality in incident hemodialysis patients","volume":"27","author":"Kim TW","year":"2016","journal-title":"J Am Soc Nephrol"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-139X.2010.00782.x"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/sdi.12529"},{"key":"e_1_2_7_12_1","first-page":"212","article-title":"Th\u00e9orie de la Similitude Biologique","volume":"3","author":"Lambert R","year":"1927","journal-title":"Ann Physiol"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.08171109"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.05581008"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.02350310"},{"key":"e_1_2_7_16_1","first-page":"8","article-title":"Effect of hyponatremia on response to volume depletion in uremic dogs","volume":"109","author":"Daugirdas JT","year":"1987","journal-title":"J Lab Clin Med"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1681.2005.04283.x"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1159\/000345484"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/hdi.12375"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10439\u2010016\u20101711\u20106"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1109\/EMBC.2013.6609798:1506\u20101509"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1038\/ki.1997.270"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0145411"},{"key":"e_1_2_7_24_1","doi-asserted-by":"crossref","first-page":"1987","DOI":"10.1681\/ASN.V4121987","article-title":"Role of adenosine in dialysis\u2010induced hypotension","volume":"4","author":"Shinzato T","year":"1994","journal-title":"J Am Soc Nephrol"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1038\/ki.1991.28"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ki.5000088"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1038\/ki.1992.437"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1017\/CBO9781316275108"},{"key":"e_1_2_7_29_1","volume-title":"Kreislaufdiagnostik mit der Farbstoffverd\u00fcnnungsmethode","author":"Hegglin R","year":"1962"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1381\/096089206777346673"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(78)80601-5"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.3109\/00365513.2013.819524"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1159\/000189320"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1159\/000066957"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.5301\/ijao.5000167"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.1111\/1744-9987.12414"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAT.0000000000000206"},{"key":"e_1_2_7_38_1","doi-asserted-by":"publisher","DOI":"10.1080\/030919099294276"},{"key":"e_1_2_7_39_1","first-page":"p6A","article-title":"The effect of limiting maximum ultrafiltration rate in an in\u2010center hemodialysis population (abstract edition)","volume":"23","author":"Pirkle JL","year":"2012","journal-title":"J Am Soc Nephrol"},{"key":"e_1_2_7_40_1","doi-asserted-by":"publisher","DOI":"10.1038\/ki.2012.42"},{"key":"e_1_2_7_41_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1523-1755.2005.00467.x"},{"key":"e_1_2_7_42_1","doi-asserted-by":"publisher","DOI":"10.1159\/000346630"}],"container-title":["Seminars in Dialysis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fsdi.12563","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/sdi.12563","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T06:38:27Z","timestamp":1695537507000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/sdi.12563"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,1]]},"references-count":41,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,1]]}},"alternative-id":["10.1111\/sdi.12563"],"URL":"https:\/\/doi.org\/10.1111\/sdi.12563","archive":["Portico"],"relation":{},"ISSN":["0894-0959","1525-139X"],"issn-type":[{"value":"0894-0959","type":"print"},{"value":"1525-139X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,1]]}}}