{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,18]],"date-time":"2025-11-18T05:55:49Z","timestamp":1763445349222},"reference-count":22,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2019,10,21]],"date-time":"2019-10-21T00:00:00Z","timestamp":1571616000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Seminars in Dialysis"],"published-print":{"date-parts":[[2019,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Parathyroid hormone (PTH) is a key player of bone remodelling in patients suffering from Chronic Kidney Disease\u2010Mineral and Bone Disorder (CKD\u2010MBD). Serum PTH concentrations are thus frequently measured in CKD patients. Nevertheless, this determination is far from simple. PTH stability can be an issue and degradation of the peptide can be important if storage is not properly done. Biologically active PTH circulates together with fragments, which can be detected by some immunoassays. There is, up to now, no standardization of the assays available on the market, which can lead to some confusion when patients are followed with different methods. The upper end of the reference ranges provided by some manufacturers have not been properly established and are sometimes far too high. Finally, PTH can be oxidized in vivo and thus become inactive, while still quantified by immunoassays. In this Editorial, we will try to highlight some of these issues on PTH measurement.<\/jats:p>","DOI":"10.1111\/sdi.12844","type":"journal-article","created":{"date-parts":[[2019,10,21]],"date-time":"2019-10-21T07:06:44Z","timestamp":1571641604000},"page":"490-492","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["PTH determination in hemodialyzed patients\u2014A laboratory perspective"],"prefix":"10.1111","volume":"32","author":[{"given":"Etienne","family":"Cavalier","sequence":"first","affiliation":[{"name":"Department of Clinical chemistry CHU de Li\u00e8ge University of Li\u00e8ge Li\u00e8ge Belgium"},{"name":"CKD\u2010MBD Working group of the European Renal Association \u2013 European Dialysis and Transplant Association (ERA\u2010EDTA)"},{"name":"International Federation of Clinical Chemistry (IFCC) Committee for Bone Metabolism (IFCC C\u2010BM)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean\u2010Claude","family":"Souberbielle","sequence":"additional","affiliation":[{"name":"Laboratoire d\u2019Explorations Fonctionnelles INSERM U1151 H\u00f4pital Necker\u2010Enfant Malades Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pierre","family":"Delanaye","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Dialysis and Transplantation CHU de Li\u00e8ge University of Li\u00e8ge Li\u00e8ge 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