{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T23:33:42Z","timestamp":1771630422136,"version":"3.50.1"},"reference-count":20,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,5,10]],"date-time":"2021-05-10T00:00:00Z","timestamp":1620604800000},"content-version":"vor","delay-in-days":9,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Seminars in Dialysis"],"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The COVID\u201019 pandemic significates an enormous number of patients with pneumonia that get complicated with severe acute respiratory distress syndrome (ARDS), some of them with refractory hypercapnia and hypoxemia that need mechanical ventilation (MV). Those patients who are not candidate to extracorporeal membrane oxygenation (ECMO), the extracorporeal removal of CO<jats:sub>2<\/jats:sub> (ECCO<jats:sub>2<\/jats:sub>R) can allow ultra protective MV to limit the transpulmonary pressures and avoid ventilatory induced lung injury (VILI).<\/jats:p><jats:p>We report a first case of prolonged ECCO<jats:sub>2<\/jats:sub>R support in 38\u00a0year male with severe COVID\u201019 pneumonia refractory to conventional support. He was admitted tachypneic and oxygen saturation 71% without supplementary oxygen. The patient's clinical condition worsens with severe respiratory failure, increasing the oxygen requirement and initiating MV in the prone position. After 21\u00a0days of protective MV, PaCO<jats:sub>2<\/jats:sub> rise to 96.8\u00a0mmHg, making it necessary to connect to an ECCO<jats:sub>2<\/jats:sub>R system coupled continuous veno\u2010venous hemodialysis (CVVHD). However, due to the lack of availability of equipment in the context of the pandemic, a pediatric gas exchange membrane adapted to CVVHD allowed to maintain the removal of CO<jats:sub>2<\/jats:sub> until completing 27\u00a0days, being finally disconnected from the system without complications and with a satisfactory evolution.<\/jats:p>","DOI":"10.1111\/sdi.12980","type":"journal-article","created":{"date-parts":[[2021,5,10]],"date-time":"2021-05-10T11:45:27Z","timestamp":1620647127000},"page":"257-262","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Extracorporeal CO<sub>2<\/sub> removal and renal replacement therapy in acute severe respiratory failure in COVID\u201019 pneumonia: Case report"],"prefix":"10.1111","volume":"34","author":[{"given":"Ignacio","family":"Gacit\u00faa","sequence":"first","affiliation":[{"name":"Department of Nephrology Hospital Cl\u00ednico Universidad de Chile Santiago de Chile 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