{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T02:01:00Z","timestamp":1747188060333,"version":"3.40.5"},"reference-count":32,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2021,7,14]],"date-time":"2021-07-14T00:00:00Z","timestamp":1626220800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Seminars in Dialysis"],"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Maintenance hemodialysis (MHD) patients face disadvantages with higher risk of acquiring SARS\u2010CoV\u20102 infection, atypical manifestations, and associated multiple comorbidities. We describe patients' outcomes with symptomatic COVID\u201019 on MHD in a large cohort of patients from India.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Data were collected prospectively from hemodialysis units in 11 public and private hospitals between March 15, 2020, and July 31, 2020. The survival determinants were analyzed using stepwise backward elimination cox\u2010regression analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 263 total patients (mean age 51.76\u2009\u00b1\u200913.63\u2009years and males 173) on MHD with symptomatic COVID\u201019, 35 (13.3%) died. Those who died were older (<jats:italic>p<\/jats:italic>\u2009=\u20090.01), had higher frequency of diabetic kidney disease (<jats:italic>p<\/jats:italic>\u2009=\u20090.001), comorbidities (<jats:italic>p<\/jats:italic>\u2009=\u20090.04), and severe COVID\u201019 (<jats:italic>p<\/jats:italic>\u00a0=\u20090.001). Mortality was higher among patients on twice\u2010weekly MHD than thrice\u2010weekly (<jats:italic>p<\/jats:italic>\u2009=\u20090.001) and dialysis through central venous catheter (CVC) as compared to arteriovenous fistula (<jats:italic>p<\/jats:italic>\u2009=\u20090.001). On multivariate analysis, CVC use (HR 2.53, 95% CI 1.26\u20135.07, <jats:italic>p<\/jats:italic>\u2009=\u20090.009), disease severity (HR\u2009=\u20093.54, 95% CI 1.52\u20138.26, <jats:italic>p<\/jats:italic>\u2009=\u20090.003), and noninvasive ventilatory support (HR 0.59, 95% CI 0.25\u20130.99, <jats:italic>p<\/jats:italic>\u2009=\u20090.049) had significant effect on mortality.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The adjusted mortality risk of COVID\u201019 in MHD patients is high in patients associated with severe COVID\u201019 and patients having CVC as vascular access.<\/jats:p><\/jats:sec>","DOI":"10.1111\/sdi.13000","type":"journal-article","created":{"date-parts":[[2021,7,14]],"date-time":"2021-07-14T12:08:44Z","timestamp":1626264524000},"page":"360-367","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Outcomes of symptomatic coronavirus disease 19 in maintenance hemodialysis patient in India"],"prefix":"10.1111","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9801-0474","authenticated-orcid":false,"given":"Narayan","family":"Prasad","sequence":"first","affiliation":[{"name":"Sanjay Gandhi Postgraduate Institute of Medical Sciences  Lucknow India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2756-117X","authenticated-orcid":false,"given":"Manas Ranjan","family":"Behera","sequence":"additional","affiliation":[{"name":"Sanjay Gandhi Postgraduate Institute of Medical Sciences  Lucknow India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mansi","family":"Bhatt","sequence":"additional","affiliation":[{"name":"Sanjay Gandhi Postgraduate Institute of Medical Sciences  Lucknow India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanjay Kumar","family":"Agarwal","sequence":"additional","affiliation":[{"name":"All India Institute of Medical Sciences  New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Gopalakrishnan","sequence":"additional","affiliation":[{"name":"Madras Medical College  Chennai India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edwin","family":"Fernando","sequence":"additional","affiliation":[{"name":"Stanley Medical College  Chennai India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arpita Roy","family":"Chaudhary","sequence":"additional","affiliation":[{"name":"Postgraduate Institute of Medical Education and Research  Kolkata India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manisha","family":"Sahay","sequence":"additional","affiliation":[{"name":"Osmania General Hospital  Hyderabad India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shivendra","family":"Singh","sequence":"additional","affiliation":[{"name":"Institute of Medical Sciences BHU  Varanasi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Apoorva","family":"Jain","sequence":"additional","affiliation":[{"name":"Sarojini Naidu Medical College  Agra India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shruti","family":"Tapiawala","sequence":"additional","affiliation":[{"name":"Global Hospital  Mumbai India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aniket","family":"Kamble","sequence":"additional","affiliation":[{"name":"Lancelot Kidney Hospital  Mumbai India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Umesh","family":"Khanna","sequence":"additional","affiliation":[{"name":"Lancelot Kidney Hospital  Mumbai India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rubina","family":"Bohra","sequence":"additional","affiliation":[{"name":"Shri Aurobindo Medical College and Postgraduate Institute  Indore India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anurag","family":"Gupta","sequence":"additional","affiliation":[{"name":"Sir Ganga Ram Hospital  New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3298-8642","authenticated-orcid":false,"given":"Urmila","family":"Anandh","sequence":"additional","affiliation":[{"name":"Yashoda Hospital  Hyderabad India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8015-9470","authenticated-orcid":false,"given":"Vivekanand","family":"Jha","sequence":"additional","affiliation":[{"name":"George Institute India, University of New South Wales  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,7,14]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"https:\/\/www.who.int\/emergencies\/diseases\/novel-coronavirus-2019. Accessed December 12 2020."},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.2648"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.6775"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.01290308"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.kint.2020.04.007"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.kint.2020.04.031"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.kint.2020.03.005"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.kint.2020.04.019"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfaa069"},{"key":"e_1_2_9_11_1","doi-asserted-by":"crossref","unstructured":"Lobo V Khanna U Rajapurkar M et al.Guidelines for dialysis with reference to COVID\u201019.2020;30:166\u2013170.","DOI":"10.4103\/ijn.IJN_166_20"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.kint.2020.04.021"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2020040520"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2020030354"},{"key":"e_1_2_9_15_1","article-title":"COVID\u201019 in hemodialysis (HD) patients: report from one HD center in Wuhan, China","author":"Ma Y","year":"2020","journal-title":"medRxiv"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.kint.2020.04.030"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2020040534"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.2001.07804.x"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/14.12.2807"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.jrn.2011.10.020"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2020.03.037"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(20)30096-6"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2001017"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ekir.2020.06.034"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.4103\/ijn.IJN_363_17"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2020040461"},{"key":"e_1_2_9_27_1","unstructured":"Revised Guidelines on Clinical Management of COVID \u2013 19.https:\/\/www.mohfw.gov.in\/pdf\/RevisedNationalClinicalManagementGuidelineforCOVID1931032020.pdf. Accessed August 15 2020."},{"key":"e_1_2_9_28_1","doi-asserted-by":"crossref","unstructured":"COVID\u201019 INDIA as on 13 December 2020:https:\/\/www.mohfw.gov.in\/last accessed on 13 December 2020.","DOI":"10.14202\/vetworld.2020.12"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.4103\/ijn.IJN_120_20"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)30211-7"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)30183-5"},{"key":"e_1_2_9_32_1","unstructured":"Horby P Lim W Emberson J et al.RECOVERYCollaborativeGroup.medRxiv2020.06.22.20137273."},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dsx.2020.06.054"}],"container-title":["Seminars in Dialysis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/sdi.13000","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/sdi.13000","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/sdi.13000","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,29]],"date-time":"2023-08-29T21:04:18Z","timestamp":1693343058000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/sdi.13000"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7,14]]},"references-count":32,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2021,9]]}},"alternative-id":["10.1111\/sdi.13000"],"URL":"https:\/\/doi.org\/10.1111\/sdi.13000","archive":["Portico"],"relation":{},"ISSN":["0894-0959","1525-139X"],"issn-type":[{"type":"print","value":"0894-0959"},{"type":"electronic","value":"1525-139X"}],"subject":[],"published":{"date-parts":[[2021,7,14]]},"assertion":[{"value":"2021-02-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-06-15","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-07-14","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}