{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T02:01:05Z","timestamp":1747188065956,"version":"3.40.5"},"reference-count":24,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,11,22]],"date-time":"2021-11-22T00:00:00Z","timestamp":1637539200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Seminars in Dialysis"],"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>MR (Magnetic resonance) peritoneography is sensible for continuous ambulatory peritoneal dialysis (CAPD)\u2010related complications, which could offer excellent soft\u2010tissue contrast and allows a multiplanar imaging evaluation of complications. However, there is no study about the optimal concentration of the gadolinium\u2010based agents nor the side effects of gadolinium\u2010based agents on peritoneum and residual renal function.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Five different groups of uremic rats and two groups of normal rats were injected with a 40\u2010ml mixture of peritoneal dialysate and gadolinium\u2010based agents at varying concentrations prior to MR peritoneography. Thereafter, MR image obtained was evaluated by two experienced radiologists blinded to the concentrations. Peritoneal morphology and thickness of the uremic rats were also assessed using hematoxylin and eosin and Masson staining. Residual renal function was evaluated using serum creatinine levels and hematoxylin and eosin (HE) staining of pathological kidney sections.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results and Conclusion<\/jats:title><jats:p>The gadolinium\u2010based agents used in this experiment have no significant effect on residual renal function. There is no obvious difference in the image quality at the different gadolinium\u2010based agents concentration. Due to the adverse effects of gadolinium\u2010based agents in the previous studies, we suggest reducing the dose of gadolinium\u2010based agents during MR peritoneography to the lowest limits.<\/jats:p><\/jats:sec>","DOI":"10.1111\/sdi.13040","type":"journal-article","created":{"date-parts":[[2021,11,23]],"date-time":"2021-11-23T07:56:51Z","timestamp":1637654211000},"page":"258-263","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Tolerance of peritoneal and residual renal function to intraperitoneal gadolinium\u2010based agents: An animal experimental study of magnetic resonance peritoneography"],"prefix":"10.1111","volume":"35","author":[{"given":"Jing","family":"Dong","sequence":"first","affiliation":[{"name":"Department of Radiology Affiliated Hospital of Southwest Medical University  Luzhou 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