{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T23:16:29Z","timestamp":1770678989381,"version":"3.49.0"},"reference-count":18,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,1,6]],"date-time":"2022-01-06T00:00:00Z","timestamp":1641427200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Seminars in Dialysis"],"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>As end\u2010stage renal disease (ESRD) patients generally have reduced responses to the vaccines, effectiveness of newly developed SARS\u2010CoV\u20102 vaccines in ESRD are also matters of curiosity. We aimed to investigate the humoral responses of our peritoneal dialysis (PD) patients to the inactivated SARS\u2010CoV\u20102 vaccine.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Humoral immune responses of 23 PD patients who received two doses of the inactivated SARS\u2010CoV\u20102 vaccine were investigated with a commercial test that measures IgG antibodies towards receptor binding domain of SARS\u2010CoV\u20102 spike protein. Seropositivity rates, antibody titers, and ESRD related clinical data were compared with 51 hemodialysis (HD) patients and 29 healthy volunteers.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Seropositivity of PD patients with the inactivated vaccine was 95.6%. Both the rate of seropositivity and SARS\u2010CoV\u20102 IgG antibody levels in PD patients were not different from the healthy controls (<jats:italic>p<\/jats:italic>\u00a0=\u20090.85 and 0.19, respectively). While seropositivity rates were not different for PD or HD patients (<jats:italic>p<\/jats:italic>\u00a0=\u20090.09), the magnitude of humoral responses was significantly higher in PD patients (<jats:italic>p<\/jats:italic>\u00a0=\u20090.0001). There were no vaccine\u2010related serious adverse events. In the 3\u2010months clinical follow\u2010up, none of the patients experienced SARS\u2010CoV\u20102 infection.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Two doses of the inactivated vaccine generate adequate humoral immune response in PD patients without any serious adverse events.<\/jats:p><\/jats:sec>","DOI":"10.1111\/sdi.13049","type":"journal-article","created":{"date-parts":[[2022,1,6]],"date-time":"2022-01-06T11:40:04Z","timestamp":1641469204000},"page":"264-268","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Antibody responses to inactivated SARS\u2010CoV\u20102 vaccine in peritoneal dialysis patients"],"prefix":"10.1111","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1948-2914","authenticated-orcid":false,"given":"Ahmet","family":"Murt","sequence":"first","affiliation":[{"name":"Division of Nephrology, Department of Internal Medicine, Cerrahpasa Medical Faculty Istanbul University\u2010Cerrahpasa  Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehmet R.","family":"Altiparmak","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Internal Medicine, Cerrahpasa Medical Faculty Istanbul University\u2010Cerrahpasa  Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dogukan","family":"Ozbey","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology, Cerrahpasa Medical Faculty Istanbul University\u2010Cerrahpasa  Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Serkan F.","family":"Yalin","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Internal Medicine Dr Lutfi Kirdar City Hospital  Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Serap","family":"Sert Yadigar","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Internal Medicine Dr Lutfi Kirdar City Hospital  Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ridvan","family":"Karaali","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases and Clinical Microbiology, Cerrahpasa Medical Faculty Istanbul University\u2010Cerrahpasa  Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bekir","family":"Kocazeybek","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology, Cerrahpasa Medical Faculty Istanbul University\u2010Cerrahpasa  Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nese","family":"Saltoglu","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases and Clinical Microbiology, Cerrahpasa Medical Faculty Istanbul University\u2010Cerrahpasa  Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meltem","family":"Pekpak","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Internal Medicine, Cerrahpasa Medical Faculty Istanbul University\u2010Cerrahpasa  Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muveddet R.","family":"Ataman","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Internal Medicine, Cerrahpasa Medical Faculty Istanbul University\u2010Cerrahpasa  Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,1,6]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0009156"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.07200520"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfimm\/iqab010"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrneph.2013.44"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.00950208"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2005.08.032"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1492-7535.2005.01155.x"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2005.02.033"},{"issue":"21","key":"e_1_2_7_10_1","first-page":"758","article-title":"Anti\u2010SARS\u2010CoV\u20102 spike protein S1 receptor\u2010binding domain antibody to an 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