{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T21:50:30Z","timestamp":1784238630793,"version":"3.55.0"},"reference-count":54,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,6,15]],"date-time":"2023-06-15T00:00:00Z","timestamp":1686787200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Seminars in Dialysis"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Dialyzer reprocessing for dialyzer reuse in the same patient has been developed since the early time in hemodialysis history to save cost and time related to reassembling the new dialyzer during that time. The procedure can reduce the first\u2010use and allergic reactions from using incompatible cellulosic dialyzer membrane by altering some manufacturing chemicals.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>All of established literatures regarding recent dialyzer reprocessing methods and considerations were extensively reviewed and summarized.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Dialyzer reprocessing can be performed by multiple protocols but involves common steps including bedside rinsing after use, cleaning, dialyzer testing to prevent excessive drop in dialyzer clearance and membrane integrity, high\u2010level disinfection or sterilization either by chemicals or heat, storage, and preparation for subsequent dialysis session by adequate rinsing to reduce the residual reprocessing chemical to the safe level. Compared with the single\u2010use strategy, evidence is conflicting for the mortality advantages or disadvantages of dialyzer reuse, with some showing increased mortality in patients receiving peracetic acid sterilization. Keys for the effective and safe dialyzer reuse involve strict adherence to specific manufacturer's protocol, adequate dialysis water quality complied with the Association for the Advancement of Medical Instrumentation standard, measurement of the total cell volume to prevent inadequate hemodialysis, and infectious control consideration. In the present era, single\u2010use strategy is increasingly adopted due to the decreased cost for dialyzer manufacturing. Environmental concerns of higher solid waste from dialyzer disposal in single\u2010use dialysis should be compared with the liquid waste from reprocessing chemicals along with plastic waste and cardboard in reuse dialysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Dialyzer reprocessing with adequate regulation is considered as an acceptable option for cost\u2010effective hemodialysis, compared with the single\u2010use strategy.<\/jats:p><\/jats:sec>","DOI":"10.1111\/sdi.13163","type":"journal-article","created":{"date-parts":[[2023,6,15]],"date-time":"2023-06-15T08:39:55Z","timestamp":1686818395000},"page":"45-53","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Dialyzer reprocessing: Considerations and pitfalls for effective and safe hemodialysis"],"prefix":"10.1111","volume":"38","author":[{"given":"Thana","family":"Thongsricome","sequence":"first","affiliation":[{"name":"Division of Nephrology, Department of Medicine, King Chulalongkorn Memorial Hospital, Thai Red Cross Society and Faculty of Medicine Chulalongkorn University  Bangkok Thailand"},{"name":"Department of Physiology, Faculty of Medicine Chulalongkorn University  Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Somchai","family":"Eiam\u2010Ong","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Medicine, King Chulalongkorn Memorial Hospital, Thai Red Cross Society and Faculty of Medicine Chulalongkorn University  Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khajohn","family":"Tiranathanagul","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Medicine, King Chulalongkorn Memorial Hospital, Thai Red Cross Society and Faculty of Medicine Chulalongkorn University  Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,6,15]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.1.5347.1716"},{"issue":"1","key":"e_1_2_9_3_1","first-page":"24","article-title":"A technique for storage and multiple re\u2010use of the kill dialyzer and blood tubing","volume":"13","author":"Pollard TL","year":"1967","journal-title":"ASAIO J"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525\u2010139X.2006.00118.x"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198005293022216"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525\u20101594.1987.tb02644.x"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1159\/000168268"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/ki.1981.73"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1159\/000168970"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/ki.1992.409"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12882\u2010015\u20100117\u20102"},{"key":"e_1_2_9_12_1","unstructured":"The Thai Renal Replacement Therapy (TRT) Committee.Thailand renal replacement therapy.2020."},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.V661578"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/978\u20103\u2010642\u201027458\u20109_10"},{"key":"e_1_2_9_15_1","first-page":"237","volume-title":"Handbook of Dialysis","author":"DeOreo PB","year":"2015"},{"key":"e_1_2_9_16_1","first-page":"270","article-title":"Peracetic acid for reuse of hemodialyzers clinical studies","volume":"30","author":"Berkseth R","year":"1984","journal-title":"Trans Am Soc Artif Intern Organs"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1177\/039139889401700604"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0272\u20106386(12)70280\u20109"},{"issue":"5","key":"e_1_2_9_19_1","first-page":"248","article-title":"Safety of dialyzer reuse with renalin\u00ae: the untold story","volume":"23","author":"Luehmann DA","year":"1994","journal-title":"Dial Transplant"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1966.03100180123046"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/152.5.1013"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197606242942602"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.30.10.956"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525\u20101594.1981.tb04001.x"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers14010165"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0272\u20106386(89)80186\u20106"},{"key":"e_1_2_9_27_1","first-page":"662","article-title":"Experience with the disinfectant peroxyacetic acid (PES) for hemodialyzer reuse","volume":"29","author":"Bauer H","year":"1983","journal-title":"Trans Am Soc Artif Intern Organs"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1097\/00002480\u2010199207000\u201000050"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1996.03540080042027"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.V9112108"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0895\u20104356(98)00162\u20100"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfh460"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2005.07.017"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.03160410"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.10391110"},{"issue":"5","key":"e_1_2_9_36_1","first-page":"650","article-title":"Long\u2010term efficacy of pre\u2010 and post\u2010dilution online hemodiafiltration with dialyzer reuse","volume":"95","author":"Tiranathanagul K","year":"2012","journal-title":"J Med Assoc Thai"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1159\/000336532"},{"issue":"1","key":"e_1_2_9_38_1","first-page":"S2","article-title":"Clinical practice guidelines for hemodialysis adequacy, update 2006","volume":"48","author":"Hemodialysis Adequacy 2006 Work Group","year":"2006","journal-title":"Am J Kidney Dis"},{"key":"e_1_2_9_39_1","first-page":"81","article-title":"Mass transport in reused dialyzers","volume":"10","author":"Gotch FA","year":"1980","journal-title":"Proc Clin Dial Transplant Forum"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.5414\/CNP61130"},{"key":"e_1_2_9_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0272\u20106386(00)70306\u20104"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.1159\/000495025"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0272\u20106386(99)70262\u20103"},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.1038\/ki.1995.72"},{"key":"e_1_2_9_45_1","doi-asserted-by":"publisher","DOI":"10.1053\/ajkd.1998.v32.pm9708616"},{"key":"e_1_2_9_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0272\u20106386(97)90308\u20105"},{"key":"e_1_2_9_47_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12882\u2010016\u20100405\u20105"},{"key":"e_1_2_9_48_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.20223311S1716d"},{"key":"e_1_2_9_49_1","unstructured":"ANSI\/AAMI RD47:2020.Reprocessing of hemodialyzers."},{"key":"e_1_2_9_50_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525\u20101594.1995.tb02331.x"},{"key":"e_1_2_9_51_1","doi-asserted-by":"publisher","DOI":"10.1159\/000168793"},{"key":"e_1_2_9_52_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2016.09.022"},{"key":"e_1_2_9_53_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471\u20102458\u20104\u201013"},{"key":"e_1_2_9_54_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.01040207"},{"key":"e_1_2_9_55_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010020\u201068408\u20101"}],"container-title":["Seminars in Dialysis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/sdi.13163","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,12]],"date-time":"2025-03-12T07:59:28Z","timestamp":1741766368000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/sdi.13163"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6,15]]},"references-count":54,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["10.1111\/sdi.13163"],"URL":"https:\/\/doi.org\/10.1111\/sdi.13163","archive":["Portico"],"relation":{},"ISSN":["0894-0959","1525-139X"],"issn-type":[{"value":"0894-0959","type":"print"},{"value":"1525-139X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,6,15]]},"assertion":[{"value":"2023-05-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-05-23","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-06-15","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}