{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,30]],"date-time":"2025-08-30T16:44:18Z","timestamp":1756572258354,"version":"3.40.5"},"reference-count":28,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2023,8,24]],"date-time":"2023-08-24T00:00:00Z","timestamp":1692835200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Seminars in Dialysis"],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Numerous factors impact the mortality and functional abilities of patients with end\u2010stage renal disease (ESRD) receiving maintenance hemodialysis (MHD). We aimed to determine the mortality rate at 1\u2009year of MHD, identify predictors of mortality, and assess functional impairments concerning activities of daily living (ADLs) and instrumental ADL (IADL).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Our study was prospective, observational cohort study that enrolled patients receiving MHD. We collected demographic, clinical, and laboratory data. We also assessed ADLs and IADLs for daily performance.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Our study included 167 patients with a mean age of 51.6\u2009\u00b1\u200913.1\u00a0years, and 56.9% were male. Of these, 80 (47.9%) were diabetic, and 145 (86.8%) were hypertensive. The mortality rate after 1\u00a0year of MHD was 10.8%, and cardiovascular causes accounted for over 70% of total deaths. Sudden cardiac death was the most frequent cause (38.9%), followed by cardiogenic shock (22.2%). Older age and low parathormone levels (&lt;300\u2009pg\/mL) were significantly associated with higher mortality rates. Mean ADL and IADL scores were 4.5\u2009\u00b1\u20091.3 and 6.3\u2009\u00b1\u20092.7, respectively. Eighteen (10.8%) and 56 (33.5%) patients had low ADL and IADL scores, respectively. Although statistically insignificant, a higher proportion of non\u2010survivors exhibited low IADL and ADL scores. Older age, longer diabetes duration, and higher BMI levels were significantly associated with lower IADL scores.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Older age and suppressed PTH levels are predictors of mortality in ESRD patients receiving MHD. These patients require regular follow\u2010ups to rule out cardiovascular morbidity. Functional impairment is prevalent but remains underdiagnosed in MHD patients. It should be monitored regularly to improve quality of life in ESRD.<\/jats:p><\/jats:sec>","DOI":"10.1111\/sdi.13173","type":"journal-article","created":{"date-parts":[[2023,8,24]],"date-time":"2023-08-24T10:29:34Z","timestamp":1692872974000},"page":"138-144","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Predictors of functional impairment and mortality in patients on maintenance hemodialysis"],"prefix":"10.1111","volume":"37","author":[{"given":"Neha","family":"Jain","sequence":"first","affiliation":[{"name":"RC Multispeciality Hospital and Trauma Centre  Bijnor India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ravi","family":"Bansal","sequence":"additional","affiliation":[{"name":"Department of Nephrology PSRI Hospital  New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanjiv","family":"Saxena","sequence":"additional","affiliation":[{"name":"Department of Nephrology PSRI Hospital  New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2513-5131","authenticated-orcid":false,"given":"Sourabh","family":"Sharma","sequence":"additional","affiliation":[{"name":"Department of Nephrology VMMC &amp; Safdarjung Hospital  New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9409-3874","authenticated-orcid":false,"given":"Sree Bhushan","family":"Raju","sequence":"additional","affiliation":[{"name":"Department of Nephrology Nizams Institute of Medical Sciences  Hyderabad India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,8,24]]},"reference":[{"issue":"4","key":"e_1_2_9_2_1","first-page":"473","article-title":"Morbidity and mortality in ESRD patients on dialysis","volume":"13","author":"Al Wakeel JS","year":"2002","journal-title":"Saudi J Kidney Dis Transpl"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ki.5001958"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197403282901301"},{"issue":"2","key":"e_1_2_9_5_1","first-page":"S1","article-title":"Excerpts from United States renal data system: 1994 annual data report","volume":"24","year":"1994","journal-title":"Am J Kidney Dis"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.01170905"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/ki.2013.252"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/ki.2014.15"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2008.07.031"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2009.1488"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1159\/000443449"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2016.10.365"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2009.06.217"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.2147\/CIA.S249137"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/ki.2014.384"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.37757\/MR2013V15.N3.4"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.V451205"},{"key":"e_1_2_9_18_1","unstructured":"World Health Organization. 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