{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T06:56:26Z","timestamp":1792133786967,"version":"4.4.0"},"reference-count":37,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Seminars in Dialysis"],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\"><jats:italic>Pantoea agglomerans<\/jats:italic><\/jats:styled-content> is an environmental pathogen known to cause infection in immunocompromised individuals, particularly after thorn injuries. However, previous data showed few cases of human disease caused by contaminated medical products such as parenteral nutrition, anesthetic agents, blood, and peritoneal dialysis solutions. Infection in hemodialysis patients is rare. In this study, we presented a detailed account of several hemodialysis patients infected with this contagious pathogen and compared them with noninfected dialysis patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We retrospectively reviewed the hospital records of 105 hemodialysis patients. Seventeen of 105 patients were diagnosed with <jats:styled-content style=\"fixed-case\"><jats:italic>P.\u2009agglomerans<\/jats:italic><\/jats:styled-content> infection. We carefully analyzed their entire in\u2010hospital course.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among infected patients, 52.9% were male with a median age of 49 (IQR: 32\u201366) years. Compared to the noninfected patients, age below 50\u2009years, prior kidney transplantation, prior immunosuppression and antibiotics use, and dialysis via a tunneled vascular catheter were the significant epidemiological features. Despite negative microbiological investigations, we suspect the possible infectious spread via infected central venous catheter was the likely infectious source. Most importantly, all patients responded well to intravenous antibiotics. Only two patients required the removal of the tunneled catheter. Their mortality rate was 0%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\"><jats:italic>P.\u2009agglomerans<\/jats:italic><\/jats:styled-content> infection, although considered rare, is becoming increasingly prevalent among dialysis patients. Its occurrence must be appraised as an infectious outbreak rather than mere contamination. Prompt treatment, source identification, and early implementation of preventive strategies should always be the goal to curtail this infection at an early stage.<\/jats:p><\/jats:sec>","DOI":"10.1111\/sdi.13182","type":"journal-article","created":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T06:58:29Z","timestamp":1696229909000},"page":"172-177","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["<scp><i>Pantoea agglomerans<\/i><\/scp>: A rare infectious outbreak affecting maintenance hemodialysis patients in a tertiary care hospital"],"prefix":"10.1111","volume":"37","author":[{"given":"Danyal","family":"Hassan","sequence":"first","affiliation":[{"name":"Department of Renal Medicine Shifa International Hospital  Islamabad 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