{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T02:22:28Z","timestamp":1777947748834,"version":"3.51.4"},"reference-count":14,"publisher":"Wiley","issue":"1-2","license":[{"start":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T00:00:00Z","timestamp":1774310400000},"content-version":"vor","delay-in-days":82,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Seminars in Dialysis"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Blood hemoglobin (Hb) levels typically increase during maintenance hemodialysis (MHD) sessions. This intradialytic Hb change (ID\u2010HbC) may increase thrombotic risks depending on its magnitude. This study investigated the magnitude.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In 115 MHD sessions with standard hemodialysis modality, relative\u2010ID\u2010HbC, which was calculated from pre\u2010 and post\u2010dialysis Hb values, was examined in relation to ultrafiltration volume normalized to dry weight (UFV\/DW).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Relative\u2010ID\u2010HbC ranged from \u22120.037 to 0.324, with a median (interquartile range) of 0.104 (0.070\u20130.177). A significant positive correlation was observed between relative\u2010ID\u2010HbC and UFV\/DW (\n                      <jats:italic>r<\/jats:italic>\n                      \u2009=\u20090.50,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), with a least\u2010squares regression slope of 3.1. In about 1\/3 sessions with UFV\/DW &gt;\u20090.05, relative\u2010ID\u2010HbC exceeded 0.2.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>More than 20% increase in Hb can occur in sessions with UFV\/DW &gt;\u20090.05, whereas the typical increase is around 3% per 1% increase in UFV\/DW. To reduce thrombotic risks, anemia therapy raising pre\u2010dialysis Hb\u2009&gt;\u200910.5\u2009g\/dL should preferably be avoided in MHD patients who require UFV\/DW &gt;\u20090.05.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/sdi.70020","type":"journal-article","created":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T07:26:24Z","timestamp":1774337184000},"page":"44-47","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Blood Hemoglobin Change During Maintenance Hemodialysis Sessions"],"prefix":"10.1111","volume":"39","author":[{"given":"Hiroyuki","family":"Koike","sequence":"first","affiliation":[{"name":"Dialysis Center, Hidakami Chuo Clinic  Iwate Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7933-6978","authenticated-orcid":false,"given":"Masayuki","family":"Tanemoto","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Internal Medicine, Tokatsu Clinic  Chiba Japan"},{"name":"Dialysis Unit Shin\u2010Kuki General Hospital  Saitama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,3,24]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2016.08.030"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/sdi.12624"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2015.07.015"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1053\/ajkd.2002.34913"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199808273390903"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.34067\/KID.0000000000000082"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/16.4.798"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12882\u2010020\u201002210\u2010z"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/hdi.13108"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/ckj\/sfaf274"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/ki.1991.28"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/hdi.12338"},{"issue":"4","key":"e_1_2_10_14_1","first-page":"279","article-title":"KDIGO Clinical Practice Guideline for Anemia in Chronic Kidney Disease","volume":"2","author":"KDIGO Anemia Work Group","year":"2012","journal-title":"Kidney International. Supplement"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2007.06.008"}],"container-title":["Seminars in Dialysis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/sdi.70020","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/sdi.70020","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/sdi.70020","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T02:50:08Z","timestamp":1777776608000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/sdi.70020"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":14,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1111\/sdi.70020"],"URL":"https:\/\/doi.org\/10.1111\/sdi.70020","archive":["Portico"],"relation":{},"ISSN":["0894-0959","1525-139X"],"issn-type":[{"value":"0894-0959","type":"print"},{"value":"1525-139X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"2025-08-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-16","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-24","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}