{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T15:22:12Z","timestamp":1791559332733,"version":"4.3.4"},"reference-count":12,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T00:00:00Z","timestamp":1777507200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T00:00:00Z","timestamp":1777507200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Seminars in Dialysis"],"published-print":{"date-parts":[[2026,5]]},"abstract":"ABSTRACT<\/jats:title>\n \n Background<\/jats:title>\n Studies suggest increased phosphate removal when using hemodiafiltration (HDF) compared with hemodialysis (HD), but a complete analytic comparison has not been reported.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n We analyzed data from a 6\u2010month prospective, multicenter, cross\u2010sectional study that enrolled patients treated with high\u2010flux HD or HDF and in whom residual kidney phosphate clearances (KrPhos) were measured. Modeling data and dietary survey data were available from 115 patients (59 treated with HD and 56 treated with HDF).<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Predialysis (midweek) serum phosphate values averaged 4.37\u2009\u00b1\u20091.00 and 4.60\u2009\u00b1\u20091.18\u2009mg\/dL in the HD and HDF groups (\n p<\/jats:italic>\n \u2009=\u2009NS). Mean prescribed phosphate binder equivalent dose (PBED) (including zero values) was 3.33\u2009\u00b1\u20092.94\u2009g\/day in HD and 2.64\u2009\u00b1\u20092.68\u2009g\/day in HDF (\n p<\/jats:italic>\n \u2009=\u20090.19). Mean modeled phosphate ingestion was similar in HD and HDF (911\u2009\u00b1\u2009231 vs. 911\u2009\u00b1\u2009300\u2009mg\/day,\n p<\/jats:italic>\n \u2009=\u2009NS), but phosphate ingestion by dietary survey was higher in HDF vs. HD (1119\u2009\u00b1\u2009520 vs. 801\u2009\u00b1\u2009420\u2009mg\/day,\n p<\/jats:italic>\n \u2009<\u20090.001). Mean predialysis serum phosphate values in patients with residual kidney function (defined as KrPhosWater\u2009>\u20091.0\u2009mL\/min) and anuric patients were similar (4.43 \u00b1 0.73 vs. 4.50\u2009\u00b1\u20091.20 mg\/dL, respectively), whereas mean prescribed PBED was lower in patients with KrPhosWater\u2009>\u20091.0\u2009mL\/min (1.83\u2009\u00b1\u20092.02 vs. 3.40\u2009\u00b1\u20092.96\u2009g\/day,\n p<\/jats:italic>\n \u2009<\u20090.01).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n Predialysis serum phosphate is not always lower in patients treated with HDF compared with HD, and this can possibly be explained by a trend to a lower prescribed PBED and\/or by a higher dietary phosphate intake.<\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/sdi.70029","type":"journal-article","created":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T05:00:50Z","timestamp":1777611650000},"page":"97-104","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Phosphate Kinetic Modeling in Patients Treated With Hemodialysis or Hemodiafiltration: A Prospective, Multicenter, Cross\u2010Sectional Study"],"prefix":"10.1111","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2695-1838","authenticated-orcid":false,"given":"J\u00f6rgen","family":"Hegbrant","sequence":"first","affiliation":[{"name":"Division of Nephrology, Department of Clinical Sciences Lund University Lund Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amparo","family":"Bernat","sequence":"additional","affiliation":[{"name":"Hospital Lluis Alcanys Xativa Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rita","family":"Simorra","sequence":"additional","affiliation":[{"name":"Primary Care Team Sarria\u2010Vallvidriera\u2010Les Planes Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Domingo","family":"Del Castillo","sequence":"additional","affiliation":[{"name":"Nephrologist (retired) C\u00f3rdoba Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose Luis","family":"Pizarro","sequence":"additional","affiliation":[{"name":"Diaverum Spain M\u00e1laga Dialysis Clinic M\u00e1laga Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos","family":"Jarava","sequence":"additional","affiliation":[{"name":"Diaverum Spain Isla de la Cartuja Dialysis Clinic Santiponce Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonia","family":"Caparros","sequence":"additional","affiliation":[{"name":"Diaverum Spain Virgen de Montserrat Dialysis Clinic Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6936-0616","authenticated-orcid":false,"given":"Giovanni F. M.","family":"Strippoli","sequence":"additional","affiliation":[{"name":"Department of Precision and Regenerative Medicine and Ionian Area (Dimepre\u2010J) University of Bari Bari Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0644-6842","authenticated-orcid":false,"given":"John T.","family":"Daugirdas","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Medicine University of Illinois College of Medicine Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,4,30]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfw347"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1159\/000499438"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/sdi.13112"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525\u2010139X.2011.00849.x"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.jrn.2022.06.006"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/sdi.13252"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2014.01.014"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/beheco\/ark016"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/1744\u20109987.14061"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfac223"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.5301\/jn.5000046"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1159\/000531355"}],"container-title":["Seminars in Dialysis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/sdi.70029","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/sdi.70029","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/sdi.70029","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,22]],"date-time":"2026-05-22T14:51:50Z","timestamp":1779461510000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/sdi.70029"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,30]]},"references-count":12,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,5]]}},"alternative-id":["10.1111\/sdi.70029"],"URL":"https:\/\/doi.org\/10.1111\/sdi.70029","archive":["Portico"],"relation":{},"ISSN":["0894-0959","1525-139X"],"issn-type":[{"value":"0894-0959","type":"print"},{"value":"1525-139X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,30]]},"assertion":[{"value":"2025-10-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-08","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-30","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}