{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T10:42:37Z","timestamp":1790073757369,"version":"4.0.1"},"reference-count":28,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2015,1,20]],"date-time":"2015-01-20T00:00:00Z","timestamp":1421712000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001807","name":"S\u00e3o Paulo Research Foundation","doi-asserted-by":"publisher","award":["2011\/13587-4"],"award-info":[{"award-number":["2011\/13587-4"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Scand J Immunol"],"published-print":{"date-parts":[[2015,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Group B <jats:italic>Streptococcus<\/jats:italic> (<jats:styled-content style=\"fixed-case\">GBS<\/jats:styled-content>)<jats:italic>, Klebsiella<\/jats:italic> spp. and <jats:italic>Pseudomonas<\/jats:italic> spp. are important aetiological agents of neonatal infections in Brazil. There is a lack of data in the literature regarding the specific transport of immunoglobulin G (IgG) against these pathogens in multiple pregnancies. Maternal (<jats:italic>n<\/jats:italic>\u00a0=\u00a055) and umbilical cord (<jats:italic>n<\/jats:italic>\u00a0=\u00a0110) blood samples were prospectively collected at birth from 55 twin pregnancies. The factors associated with cord levels and transfer ratios of IgG against <jats:styled-content style=\"fixed-case\">GBS<\/jats:styled-content>,<jats:italic> Klebsiella<\/jats:italic> and <jats:italic>Pseudomonas<\/jats:italic> were examined. The IgG umbilical cord serum levels specific to <jats:styled-content style=\"fixed-case\">GBS<\/jats:styled-content><jats:italic>, Klebsiella <\/jats:italic><jats:styled-content style=\"fixed-case\">LPS<\/jats:styled-content> and <jats:italic>Pseudomonas <\/jats:italic><jats:styled-content style=\"fixed-case\">LPS<\/jats:styled-content> were significantly associated with maternal\u2010specific IgG concentrations and the presence of diabetes. The anti\u2010<jats:italic>Klebsiella<\/jats:italic> IgG cord serum concentrations were also related to birthweight and the presence of hypertension. The transfer ratios against <jats:styled-content style=\"fixed-case\">GBS<\/jats:styled-content> and <jats:italic>Pseudomonas <\/jats:italic><jats:styled-content style=\"fixed-case\">LPS<\/jats:styled-content> were associated with maternal\u2010specific IgG concentrations. The transfer ratios for <jats:styled-content style=\"fixed-case\">GBS<\/jats:styled-content> and <jats:italic>Pseudomonas <\/jats:italic><jats:styled-content style=\"fixed-case\">LPS<\/jats:styled-content> were associated with gestational age at delivery and the presence of diabetes, respectively. None of the examined parameters were related to <jats:italic>Klebsiella <\/jats:italic><jats:styled-content style=\"fixed-case\">LPS<\/jats:styled-content> transfer ratios. We conclude that in twin pregnancies, specific maternal IgG serum concentrations and diabetes were the parameters associated with umbilical cord serum IgG concentrations reactive with the three pathogens investigated. All the other parameters investigated showed different associations with neonatal\u2010specific IgG levels according to the antigen studied. There was no uniformity of the investigated parameters regarding association with placental IgG transfer ratios against the <jats:styled-content style=\"fixed-case\">GBS<\/jats:styled-content>,<jats:italic> Pseudomonas <\/jats:italic><jats:styled-content style=\"fixed-case\">LPS<\/jats:styled-content> and <jats:italic>Klebsiella <\/jats:italic><jats:styled-content style=\"fixed-case\">LPS<\/jats:styled-content>.<\/jats:p>","DOI":"10.1111\/sji.12258","type":"journal-article","created":{"date-parts":[[2014,11,29]],"date-time":"2014-11-29T05:53:07Z","timestamp":1417240387000},"page":"135-141","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Placental Transfer of IgG Antibodies Specific to <i>Klebsiella<\/i> and <i>Pseudomonas <\/i><scp>LPS<\/scp> and to Group B <i>Streptococcus<\/i> in Twin Pregnancies"],"prefix":"10.1111","volume":"81","author":[{"given":"S. C. L.","family":"Stach","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology S\u00e3o Paulo University Medical School Sao Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. L.","family":"Brizot","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology S\u00e3o Paulo University Medical School Sao Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. W.","family":"Liao","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology S\u00e3o Paulo University Medical School Sao Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Palmeira","sequence":"additional","affiliation":[{"name":"Department of Pediatrics S\u00e3o Paulo University Medical School Sao Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. P. V.","family":"Francisco","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology S\u00e3o Paulo University Medical School Sao Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. M. S.","family":"Carneiro\u2010Sampaio","sequence":"additional","affiliation":[{"name":"Department of Pediatrics S\u00e3o Paulo University Medical School Sao Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Zugaib","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology S\u00e3o Paulo University Medical School Sao Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,1,20]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"3","volume-title":"Multiple Pregnancy: Epidemiology, Gestation & Perinatal Outcome","author":"Alexander GR","year":"2006"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2013.10.005"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajic.2006.06.013"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhin.2007.01.014"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0068144"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/eji.1830260718"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0897.1996.tb00172.x"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006454-200007000-00010"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.109.1.79"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2007.01556.x"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1515\/jpme.1990.18.3.165"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003081-199803000-00017"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3083.2010.02410.x"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.51.5.354"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/aji.12305"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-3083.1998.00353.x"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-006-0250-9"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1086\/422756"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1086\/323350"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-695X.2011.00807.x"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0b013e3181dc4f77"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/928187"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/0168-8227(90)90006-F"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2249.1994.tb06133.x"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1179\/027249302125001985"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0264-410X(01)00418-2"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02888119"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1086\/322808"}],"container-title":["Scandinavian Journal of Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fsji.12258","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/sji.12258","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,6]],"date-time":"2023-10-06T17:46:18Z","timestamp":1696614378000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/sji.12258"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,1,20]]},"references-count":28,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2015,2]]}},"alternative-id":["10.1111\/sji.12258"],"URL":"https:\/\/doi.org\/10.1111\/sji.12258","archive":["Portico"],"relation":{},"ISSN":["0300-9475","1365-3083"],"issn-type":[{"value":"0300-9475","type":"print"},{"value":"1365-3083","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,1,20]]},"assertion":[{"value":"2014-09-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2014-11-15","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2015-01-20","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}